Attitude to vaccination against COVID-19 in patients with non-psychotic mental disorders

N. B. Khalezova, Z. E. Kostyleva, M. Kissin, E. Boeva
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Abstract

The COVID-19 pandemic has exacerbated the increasing prevalence of non-psychotic mental disorders and the rise of antivaccination tendencies.The aim of the study was to describe the attitude to vaccination against COVID-19 in patients with non-psychotic mental disorders, as well as in mentally healthy individuals.Materials and methods: a survey was conducted of 100 outpatient patients with psychiatric diagnoses of non-psychotic level: organic mental disorders (14), affective disorders (38), neurotic and stress-related disorders (48), as well as 30 people without mental disorders.Results and discussion. There was no association between the severity of COVID-19 and an adverse reaction to the vaccine. A high incidence of skepticism about vaccination against COVID-19 was noted in women, in the older age group, in people with higher education and highly qualified work, but poorly informed about immunoprophylaxis. Post-vaccination complications (fever, general weakness) after immunization against COVID-19 were more often detected in patients with affective disorders, however, this group of patients showed the most loyal attitude to vaccination. Patients with organic mental disorders shown the lowest degree of approval of vaccination against COVID-19, they cited fear of possible «side effects» and «lack of proven benefit» as the main reason for not being vaccinated.Conclusion. Vaccination of the population of all countries affected by COVID-19 has exacerbated such a phenomenon as doubt about the benefits of immunoprophylaxis. The results of the article can be extrapolated to the future development of new drugs in the field of immunoprophylaxis.
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非精神病性精神障碍患者对接种 COVID-19 疫苗的态度
COVID-19 大流行加剧了非精神病性精神障碍发病率的上升和反疫苗接种倾向的抬头。本研究旨在描述非精神病性精神障碍患者和精神健康者对接种 COVID-19 疫苗的态度。材料和方法:对 100 名被诊断患有非精神病性精神障碍的门诊病人进行了调查:器质性精神障碍(14 人)、情感障碍(38 人)、神经症和压力相关障碍(48 人),以及 30 名无精神障碍的人。COVID-19 的严重程度与疫苗不良反应之间没有关联。对接种 COVID-19 疫苗持怀疑态度的高发人群包括女性、老年人、受过高等教育和从事高素质工作的人,但他们对免疫预防知识知之甚少。接种 COVID-19 疫苗后出现并发症(发烧、全身乏力)的情况多见于情感障碍患者,但这类患者对接种疫苗的态度最为积极。器质性精神障碍患者对接种 COVID-19 疫苗的认可度最低,他们认为害怕可能出现的 "副作用 "和 "缺乏经证实的益处 "是不接种疫苗的主要原因。在所有受 COVID-19 影响的国家,接种疫苗加剧了对免疫预防益处的怀疑。文章的研究结果可用于未来免疫预防领域新药的开发。
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来源期刊
HIV Infection and Immunosuppressive Disorders
HIV Infection and Immunosuppressive Disorders Medicine-Infectious Diseases
CiteScore
0.70
自引率
0.00%
发文量
37
期刊介绍: In the scientific-practical journal "HIV Infection and Immunosuppressive Disorders", published various issues of HIV medicine (epidemiology, molecular mechanisms of pathogenesis to the development of educational programs) leading scientists of Russia and countries of CIS, USA, as well as practical healthcare professionals working in research centers, research institutes, universities, clinics where done basic medical work. A special place on the pages of the publication is given to basic and clinical research, analytical reviews of contemporary and foreign reports, the provision of medical care for various diseases.
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