Clinico Pathological Study of Solitary Thyroid Nodule - A Prospective Study of 50 Cases.

Md Asaduzzaman, Md Moshiur Rahman, Mohammad Abdus Salam, Mahmudul Hasan Suzan
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Abstract

Background: A common Presentation of thyroid disorder is solitary nodule. A discrete swelling in an impalpable gland is termed as solitary nodule of thyroid. The majority of solitary thyroid nodule are benign. The incidence of malignancy is more common in female with mean age 35 years. Timely intervention in nodular lesion of thyroid can significantly reduce morbidity and mortality.Objectives: The objective of this study was to evaluate the clinicopathological aspects of solitary thyroid nodule.Materials and Methods: This study was conducted in the department of otolaryngology and general surgery of Shaheed Monsur Ali Medical College and Hospital in 50 patients with Solitary Thyroid Nodule from July 2016 to July 2019. All the patients those who were diagnosed solitary thyroid nodule underwent thyroid surgery after through clinical evaluation, USG and FNAC. The histopathological reports were evaluated and correlated with clinical diagnosis and discussed.Results: Out of 50 patients’ majority were female only 8 were male patients. Peak incidence observed in the age group 30 to 40 years. Most of the patients presented with a swelling in front of neck 100% followed by pain 8%, dysphagia 4% and change of voice 4%. Swelling is located in the right lobe 70% followed by left lobe 26%. On FNAC examination they were presented with colloid nodular goitre 66%, follicular neoplasm 14%, thyroiditis 8%, papillary carcinoma 4% & cystic lesions 8%. But final histopathological report showed highest 30 (60%) cases was nodular goiter then follicular adenoma 10 (20%) and 6 (12%) were malignant.Conclusion: From this study we considered that STN is present most commonly in female. Most of them are benign, but remarkable proportion 12% of solitary thyroid nodule were malignant, so careful assessment of thyroid nodule is important for early diagnosis and treatment. KYAMC Journal Volume: 14, No: 03, October 2023: 161-164.
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孤立性甲状腺结节的临床病理研究--对 50 例病例的前瞻性研究
背景:甲状腺单发结节是甲状腺疾病的常见表现。甲状腺单发性结节是指在不明显的腺体上出现不连续的肿物。大多数单发性甲状腺结节是良性的。女性恶性肿瘤的发病率较高,平均年龄为35岁。及时干预甲状腺结节病变可以大大降低发病率和死亡率:本研究旨在评估单发甲状腺结节的临床病理方面:本研究于2016年7月至2019年7月在沙希德-蒙苏尔-阿里医学院和医院的耳鼻喉科和普通外科进行,共收治了50例单发性甲状腺结节患者。所有被确诊为单发性甲状腺结节的患者都在经过临床评估、USG和FNAC检查后接受了甲状腺手术。对组织病理学报告进行了评估,并将其与临床诊断进行了关联和讨论:在50名患者中,大多数为女性,只有8名男性患者。发病高峰出现在 30 至 40 岁年龄组。大多数患者表现为颈前肿胀,占 100%,其次是疼痛,占 8%,吞咽困难占 4%,变声占 4%。肿胀位于右叶,占 70%,其次是左叶,占 26%。在FNAC检查中,66%的患者表现为胶状结节性甲状腺肿,14%为滤泡性肿瘤,8%为甲状腺炎,4%为乳头状癌,8%为囊性病变。但最终的组织病理报告显示,结节性甲状腺肿的病例最多,为30例(60%),然后是滤泡性腺瘤10例(20%)和恶性肿瘤6例(12%):通过这项研究,我们认为 STN 最常见于女性。大多数甲状腺结节为良性,但有12%的单发甲状腺结节为恶性,因此仔细评估甲状腺结节对于早期诊断和治疗非常重要。
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