Immunological storm and multiple organ damage by COVID-19

Medicine in Omics Pub Date : 2024-08-01 Epub Date: 2024-01-25 DOI:10.1016/j.meomic.2024.100034
A. Yaser Arafath , S. Aifa Fathima , Anushara Prabhakaran , Saqib Hassan , Ragothaman Prathiviraj , George Seghal Kiran , Joseph Selvin
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Abstract

The official recording outbreak COVID-19 virus was in Dec 2019. When it affects humans, it affects almost all age groups, especially aged people. COVID-19 becomes a Global pandemic within a short period. The primary consequence of this infection is that it targets the individual's respiratory system and causes severe acute respiratory syndrome (SARS-CoV-2). Research efforts were made internationally to find a proper vaccine. Here, with the mechanism of action, this review provides the infection mechanism, Immunological changes, and associated organ damage.

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Covid-19造成的免疫风暴和多器官损伤
正式记录 COVID-19 病毒爆发是在 2019 年 12 月。当病毒感染人类时,几乎会影响所有年龄段的人群,尤其是老年人。COVID-19 在短时间内成为全球大流行病。这种感染的主要后果是针对个人的呼吸系统,导致严重急性呼吸系统综合征(SARS-CoV-2)。为了找到合适的疫苗,国际上进行了大量的研究工作。在此,本综述将结合其作用机制,介绍感染机制、免疫学变化和相关器官损伤。
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