Musculoskeletal infections through direct inoculation.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-01-30 DOI:10.1007/s00256-024-04591-w
Nuran Sabir, Zehra Akkaya
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Abstract

Musculoskeletal infections consist of different clinical conditions that are commonly encountered in daily clinical settings. As clinical findings and even laboratory tests cannot always be specific, imaging plays a crucial role in the diagnosis and treatment of these cases. Musculoskeletal infections most commonly occur secondary to direct inoculation into the skin involuntarily affected by trauma, microorganism, foreign bodies, or in diabetic ulcers; direct infections can also occur from voluntary causes due to surgery, vaccinations, or other iatrogenic procedures. Hematogenous spread of infection from a remote focus can also be a cause for musculoskeletal infections. Risk factors for soft tissue and bone infections include immunosuppression, old age, corticosteroid use, systemic illnesses, malnutrition, obesity, and burns. Most literature discusses musculoskeletal infections according to the diagnostic tools or forms of infection seen in different soft tissue anatomical planes or bones. This review article aims to evaluate musculoskeletal infections that occur due to direct inoculation to the musculoskeletal tissues, by focusing on the traumatic mechanism with emphasis on the radiological findings.

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通过直接接种感染肌肉骨骼。
肌肉骨骼感染包括不同的临床症状,这些症状在日常临床环境中经常会遇到。由于临床表现甚至实验室检查都不一定具有特异性,因此影像学检查在这些病例的诊断和治疗中起着至关重要的作用。肌肉骨骼感染最常见的原因是由于外伤、微生物、异物或糖尿病溃疡导致皮肤不自主地直接接种;也可能是由于手术、疫苗接种或其他先天性手术导致的直接感染。远处病灶的血源性感染传播也可能是肌肉骨骼感染的原因之一。软组织和骨骼感染的危险因素包括免疫抑制、高龄、使用皮质类固醇、全身性疾病、营养不良、肥胖和烧伤。大多数文献根据诊断工具或不同软组织解剖平面或骨骼的感染形式来讨论肌肉骨骼感染。这篇综述文章旨在评估因直接接种到肌肉骨骼组织而发生的肌肉骨骼感染,重点关注创伤机制和放射学发现。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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