Naltrexone, acamprosate show strongest results in review of alcohol use disorder treatments

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Abstract

A systematic review and meta-analysis of approved and off-label medication treatments for alcohol use disorder has concluded that oral naltrexone and acamprosate have the strongest evidence for reducing alcohol consumption. Trials that directly compared naltrexone and acamprosate did not establish superiority of one of the medications.

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纳曲酮、阿坎酸在酒精使用障碍治疗综述中显示出最强效果
一项对已获批准的和标示外的酒精使用障碍药物治疗方法进行的系统回顾和荟萃分析得出结论,口服纳曲酮和阿坎酸酯在减少酒精消费方面具有最有力的证据。直接比较纳曲酮和阿坎酸的试验并未确定其中一种药物的优越性。
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