Huanyang Li , Junlei Chen , Xianjie Fu , Zhaoyang Wang , Caixia Du , Mao Fu , Liejun Huang , Chunmao Yuan , Jue Yang , Xiaojiang Hao , Wei Gu
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引用次数: 0
Abstract
A phytochemical investigation on the whole plant of Paraboea rufescens led to the isolation of a new compound Paraboside C (1) and eight known compounds, which including two phenylpropanoid glycosides (2 and 3), two glycosides (4 and 5), three triterpenoids (6–8), and one ethyl cyclohexanol derivative (9). Their structures were elucidated based on extensive spectroscopic methods (NMR, MS, UV, IR and ECD experiments) and comparison with literature data. Compounds 2 and 5 exhibited significant neuroprotective activities against corticosterone induced PC12 cells, which presenting a dose-dependent effect. The chemotaxonomic significance of the isolated compounds were also been discussed.
期刊介绍：
Biochemical Systematics and Ecology is devoted to the publication of original papers and reviews, both submitted and invited, in two subject areas: I) the application of biochemistry to problems relating to systematic biology of organisms (biochemical systematics); II) the role of biochemistry in interactions between organisms or between an organism and its environment (biochemical ecology).
In the Biochemical Systematics subject area, comparative studies of the distribution of (secondary) metabolites within a wider taxon (e.g. genus or family) are welcome. Comparative studies, encompassing multiple accessions of each of the taxa within their distribution are particularly encouraged. Welcome are also studies combining classical chemosystematic studies (such as comparative HPLC-MS or GC-MS investigations) with (macro-) molecular phylogenetic studies. Studies that involve the comparative use of compounds to help differentiate among species such as adulterants or substitutes that illustrate the applied use of chemosystematics are welcome. In contrast, studies solely employing macromolecular phylogenetic techniques (gene sequences, RAPD studies etc.) will be considered out of scope. Discouraged are manuscripts that report known or new compounds from a single source taxon without addressing a systematic hypothesis. Also considered out of scope are studies using outdated and hard to reproduce macromolecular techniques such as RAPDs in combination with standard chemosystematic techniques such as GC-FID and GC-MS.
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