Autistic traits and event-related potentials in the general population: A scoping review and meta-analysis

IF 2.7 3区医学 Q1 BEHAVIORAL SCIENCES Biological Psychology Pub Date : 2024-02-01 DOI:10.1016/j.biopsycho.2024.108758

Prune Mazer , Helena Garcez , Inês Macedo , Rita Pasion , Celeste Silveira , Frederieke Sempf , Fernando Ferreira-Santos

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Abstract

Background

Differences in short and long-latency Event-Related Potentials (ERPs) can help us infer abnormalities in brain processing, considering early and later stages of stimuli processing across tasks and conditions. In autism research, the adult population remains largely understudied compared to samples at early stages of development. In this context, this scoping review briefly summarises what has been described in community and subclinical adult samples of autism.

Method

The current scoping review and meta-analysis includes 50 records (N = 1652) and comprehensively explores short and long-latency ERP amplitudes and their relationship with autistic traits in adult community samples.

Results

This meta-analysis identified, with small to medium effect sizes, distinctive patterns in late ERP amplitudes, indicating enhanced responses to visual stimuli and the opposite patterns to auditory tasks in the included sample. Additionally, a pattern of higher amplitudes was also found for the component P3b in autistic traits.

Discussion

Differential effects in visual and auditory domains are explored in light of the predictive processing framework for Autism. It remains possible that different brain mechanisms operate to explain symptoms related with different sensory modalities. P3b is discussed as a possible component of interest in future studies as it revealed a more robust effect for differentiating severity in the expression of autistic traits in adulthood.

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普通人群中的自闭症特征与事件相关电位：范围综述与元分析

背景短时程和长时程事件相关电位（ERP）的差异可以帮助我们推断大脑处理过程中的异常情况，并在不同任务和条件下考虑刺激处理的早期和后期阶段。在自闭症研究中，与早期发育阶段的样本相比，成年人群的研究在很大程度上仍然不足。在这种情况下，本范围综述简要总结了自闭症社区和亚临床成人样本中的描述。方法目前的范围综述和荟萃分析包括 50 项记录（N=1652），全面探讨了成人社区样本中的短时程和长时程 ERP 振幅及其与自闭症特征的关系。讨论根据自闭症的预测处理框架，探讨了视觉和听觉领域的差异效应。不同的大脑机制仍有可能解释与不同感官模式相关的症状。由于 P3b 在区分成年期自闭症特征表现的严重程度方面具有更强的作用，因此将其作为未来研究的一个可能的关注点进行讨论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biological Psychology 医学-行为科学

CiteScore

4.20

自引率

11.50%

发文量

146

审稿时长

3 months

期刊介绍： Biological Psychology publishes original scientific papers on the biological aspects of psychological states and processes. Biological aspects include electrophysiology and biochemical assessments during psychological experiments as well as biologically induced changes in psychological function. Psychological investigations based on biological theories are also of interest. All aspects of psychological functioning, including psychopathology, are germane. The Journal concentrates on work with human subjects, but may consider work with animal subjects if conceptually related to issues in human biological psychology.