Driving-Related Glucose Patterns Among Older Adults with Type 1 Diabetes.

IF 5.7 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetes technology & therapeutics Pub Date : 2024-05-01 Epub Date: 2024-03-01 DOI:10.1089/dia.2023.0416
Hye Jin Kwon, Steven Trawley, Sara Vogrin, Andisheh Mohammad Alipoor, Peter G Colman, Spiros Fourlanos, Charlotte A Grills, Melissa H Lee, Richard J MacIsaac, David N O'Neal, Niamh A O'Regan, Vijaya Sundararajan, Glenn M Ward, Sybil A McAuley
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Abstract

Older adults with type 1 diabetes may face challenges driving safely. Glucose "above-5-to-drive" is often recommended for insulin-treated diabetes to minimize hypoglycemia while driving. However, the effectiveness of this recommendation among older adults has not been evaluated. Older drivers with type 1 diabetes were assessed while using sensor-augmented insulin pumps during a 2-week clinical trial run-in. Twenty-three drivers (median age 69 years [interquartile range; IQR 65-72]; diabetes duration 37 years [20-45]) undertook 618 trips (duration 10 min [5-21]). Most trips (n = 535; 87%) were <30 min duration; 9 trips (1.5%) exceeded 90 min and 3 trips (0.5%) exceeded 120 min. Pre-trip continuous glucose monitoring (CGM) was >5.0 mmol/L for 577 trips (93%) and none of these had CGM <3.9 mmol/L during driving (including 8 trips >90 min and 3 trips >120 min). During 41 trips with pre-trip CGM ≤5.0 mmol/L, 11 trips had CGM <3.9 mmol/L. Seventy-one CGM alerts occurred during 60 trips (10%), of which 54 of 71 alerts (76%) were unrelated to hypoglycemia. Our findings support a glucose "above-5-to-drive" recommendation to avoid CGM-detected hypoglycemia among older drivers, including for prolonged drives, and highlight the importance of active CGM low-glucose alerts to prevent hypoglycemia during driving. Driving-related CGM usability and alert functionality warrant investigation. Clinical trial ACTRN1261900515190.

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患有 1 型糖尿病的老年人开车时的血糖模式。
患有 1 型糖尿病的老年人可能会面临安全驾驶的挑战。通常建议接受胰岛素治疗的糖尿病患者将血糖控制在 "5 以上才能驾车",以减少驾车时的低血糖。然而,这一建议在老年人中的有效性尚未得到评估。在为期两周的临床试验期间,对患有 1 型糖尿病的老年驾驶员在使用传感器增强型胰岛素泵时进行了评估。23 名驾驶员(中位年龄 69 岁 [IQR:65-72];糖尿病病程 37 年 [20-45])进行了 618 次驾驶(持续时间 10 分钟 [5-21])。大多数行程(n = 535;87%)中有 577 次(93%)的血糖值为 5.0 mmol/L,其中没有一次在 90 分钟内使用 CGM,有三次在 120 分钟以上。)在 41 次旅行中,旅行前 CGM ≤5.0 mmol/L,11 次旅行中 CGM
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来源期刊
Diabetes technology & therapeutics
Diabetes technology & therapeutics 医学-内分泌学与代谢
CiteScore
10.60
自引率
14.80%
发文量
145
审稿时长
3-8 weeks
期刊介绍: Diabetes Technology & Therapeutics is the only peer-reviewed journal providing healthcare professionals with information on new devices, drugs, drug delivery systems, and software for managing patients with diabetes. This leading international journal delivers practical information and comprehensive coverage of cutting-edge technologies and therapeutics in the field, and each issue highlights new pharmacological and device developments to optimize patient care.
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