Combating COVID-19 Crisis using Artificial Intelligence (AI) Based Approach: Systematic Review.

IF 2.9 4区 医学 Q3 CHEMISTRY, MEDICINAL Current topics in medicinal chemistry Pub Date : 2024-01-01 DOI:10.2174/0115680266282179240124072121
Kavya Singh, Navjeet Kaur, Ashish Prabhu
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Abstract

Background: SARS-CoV-2, the unique coronavirus that causes COVID-19, has wreaked damage around the globe, with victims displaying a wide range of difficulties that have encouraged medical professionals to look for innovative technical solutions and therapeutic approaches. Artificial intelligence-based methods have contributed a significant part in tackling complicated issues, and some institutions have been quick to embrace and tailor these solutions in response to the COVID-19 pandemic's obstacles. Here, in this review article, we have covered a few DL techniques for COVID-19 detection and diagnosis, as well as ML techniques for COVID-19 identification, severity classification, vaccine and drug development, mortality rate prediction, contact tracing, risk assessment, and public distancing. This review illustrates the overall impact of AI/ML tools on tackling and managing the outbreak.

Purpose: The focus of this research was to undertake a thorough evaluation of the literature on the part of Artificial Intelligence (AI) as a complete and efficient solution in the battle against the COVID-19 epidemic in the domains of detection and diagnostics of disease, mortality prediction and vaccine as well as drug development.

Methods: A comprehensive exploration of PubMed, Web of Science, and Science Direct was conducted using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) regulations to find all possibly suitable papers conducted and made publicly available between December 1, 2019, and August 2023. COVID-19, along with AI-specific words, was used to create the query syntax.

Results: During the period covered by the search strategy, 961 articles were published and released online. Out of these, a total of 135 papers were chosen for additional investigation. Mortality rate prediction, early detection and diagnosis, vaccine as well as drug development, and lastly, incorporation of AI for supervising and controlling the COVID-19 pandemic were the four main topics focused entirely on AI applications used to tackle the COVID-19 crisis. Out of 135, 60 research papers focused on the detection and diagnosis of the COVID-19 pandemic. Next, 19 of the 135 studies applied a machine-learning approach for mortality rate prediction. Another 22 research publications emphasized the vaccine as well as drug development. Finally, the remaining studies were concentrated on controlling the COVID-19 pandemic by applying AI AI-based approach to it.

Conclusion: We compiled papers from the available COVID-19 literature that used AI-based methodologies to impart insights into various COVID-19 topics in this comprehensive study. Our results suggest crucial characteristics, data types, and COVID-19 tools that can aid in medical and translational research facilitation.

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利用基于人工智能(AI)的方法应对 COVID-19 危机:系统回顾。
背景:SARS-CoV-2 是一种导致 COVID-19 的独特冠状病毒,它在全球范围内造成了破坏,受害者表现出各种各样的困难,这促使医疗专业人员寻找创新的技术解决方案和治疗方法。以人工智能为基础的方法在解决复杂问题方面做出了重要贡献,一些机构已迅速接受并定制了这些解决方案,以应对 COVID-19 大流行带来的障碍。在这篇综述文章中,我们介绍了一些用于 COVID-19 检测和诊断的 DL 技术,以及用于 COVID-19 识别、严重程度分类、疫苗和药物开发、死亡率预测、接触者追踪、风险评估和公众疏远的 ML 技术。本综述说明了人工智能/ML 工具对应对和管理疫情的整体影响。目的:本研究的重点是对人工智能(AI)作为应对 COVID-19 疫情的完整、高效解决方案的文献进行全面评估,涉及疾病检测和诊断、死亡率预测、疫苗和药物开发等领域:方法:采用PRISMA(系统综述和Meta分析首选报告项目)规定,对PubMed、Web of Science和Science Direct进行了全面探索,以找到2019年12月1日至2023年8月期间公开发表的所有可能合适的论文。COVID-19以及人工智能专用词被用来创建查询语法:在搜索策略覆盖的时间段内,共有 961 篇文章在网上发表和发布。其中,共有 135 篇论文被选中进行进一步调查。死亡率预测、早期检测和诊断、疫苗和药物开发,以及最后,将人工智能用于监督和控制 COVID-19 大流行,这四个主题完全集中在用于应对 COVID-19 危机的人工智能应用上。在 135 篇研究论文中,有 60 篇侧重于 COVID-19 大流行病的检测和诊断。其次,135 项研究中有 19 项采用了机器学习方法来预测死亡率。另有 22 篇研究论文强调了疫苗和药物的开发。最后,其余的研究集中于通过应用基于人工智能的 AI 方法来控制 COVID-19 大流行:在这项综合研究中,我们汇编了现有 COVID-19 文献中使用基于人工智能的方法对各种 COVID-19 主题进行深入研究的论文。我们的研究结果表明,COVID-19 的关键特征、数据类型和工具有助于医学研究和转化研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.40
自引率
2.90%
发文量
186
审稿时长
3-8 weeks
期刊介绍: Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.
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