J-domain proteins: From molecular mechanisms to diseases

IF 3.3 3区生物学 Q3 CELL BIOLOGY Cell Stress & Chaperones Pub Date : 2024-02-01 DOI:10.1016/j.cstres.2023.12.002

Jaroslaw Marszalek , Paolo De Los Rios , Douglas Cyr , Matthias P. Mayer , Vasista Adupa , Claes Andréasson , Gregory L. Blatch , Janice E.A. Braun , Jeffrey L. Brodsky , Bernd Bukau , J. Paul Chapple , Charlotte Conz , Sébastien Dementin , Pierre Genevaux , Olivier Genest , Pierre Goloubinoff , Jason Gestwicki , Colin M. Hammond , Justin K. Hines , Koji Ishikawa , Harm H. Kampinga

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Abstract

J-domain proteins (JDPs) are the largest family of chaperones in most organisms, but much of how they function within the network of other chaperones and protein quality control machineries is still an enigma. Here, we report on the latest findings related to JDP functions presented at a dedicated JDP workshop in Gdansk, Poland. The report does not include all (details) of what was shared and discussed at the meeting, because some of these original data have not yet been accepted for publication elsewhere or represented still preliminary observations at the time.

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J-结构域蛋白：从分子机制到疾病

J-结构域蛋白（JDPs）是大多数生物中最大的伴侣蛋白家族，但它们如何在其他伴侣蛋白和蛋白质质量控制机制的网络中发挥作用仍是一个谜。在此，我们将报告在波兰格但斯克专门举行的 JDP 研讨会上与 JDP 功能相关的最新发现。本报告不包括会议上分享和讨论的全部内容（细节），因为其中一些原始数据尚未被其他地方接受发表，或者当时还只是初步观察结果。

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来源期刊

Cell Stress & Chaperones 生物-细胞生物学

CiteScore

7.60

自引率

2.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Cell Stress and Chaperones is an integrative journal that bridges the gap between laboratory model systems and natural populations. The journal captures the eclectic spirit of the cellular stress response field in a single, concentrated source of current information. Major emphasis is placed on the effects of climate change on individual species in the natural environment and their capacity to adapt. This emphasis expands our focus on stress biology and medicine by linking climate change effects to research on cellular stress responses of animals, micro-organisms and plants.