Alejandra Gatica , Carlos Muñoz-Valdivia , Nicolette Van Sint Jan , Sandra Ramos
{"title":"Perfusión dirigida por objetivos: práctica actual en técnicas de circulación extracorpórea","authors":"Alejandra Gatica , Carlos Muñoz-Valdivia , Nicolette Van Sint Jan , Sandra Ramos","doi":"10.1016/j.rmclc.2023.11.003","DOIUrl":null,"url":null,"abstract":"<div><p>Extracorporeal circulation (ECC) is an essential component of cardiac surgery since it allows life support to be maintained during the induced cardiac arrest necessary to perform cardiosurgical interventions. However, CPB presents adverse effects at a local and systemic level because its components produce alterations at the macro- and microcirculation levels, potentially leading to hypoperfusion. The goal-directed perfusion (GDP) technique seeks to personalize hemodynamic management according to predefined goals, thereby optimizing tissue oxygenation and perfusion during CPB. This implies constant monitoring of key parameters, to make real-time changes to perfusion strategies. Over the past 10 years, the benefits of using GDP have been explored and its superiority over the traditional approach visualized. The objective of this article is to describe GDP practice in monitoring during CPB. We will focus on the existing variables monitored under the GDP concept, applying and manipulating them to optimize tissue perfusion in real-time.</p></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"35 1","pages":"Pages 8-13"},"PeriodicalIF":0.2000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0716864024000026/pdfft?md5=cd170c1a814ed9c7e318dcc5223097bd&pid=1-s2.0-S0716864024000026-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Medica Clinica Las Condes","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0716864024000026","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Extracorporeal circulation (ECC) is an essential component of cardiac surgery since it allows life support to be maintained during the induced cardiac arrest necessary to perform cardiosurgical interventions. However, CPB presents adverse effects at a local and systemic level because its components produce alterations at the macro- and microcirculation levels, potentially leading to hypoperfusion. The goal-directed perfusion (GDP) technique seeks to personalize hemodynamic management according to predefined goals, thereby optimizing tissue oxygenation and perfusion during CPB. This implies constant monitoring of key parameters, to make real-time changes to perfusion strategies. Over the past 10 years, the benefits of using GDP have been explored and its superiority over the traditional approach visualized. The objective of this article is to describe GDP practice in monitoring during CPB. We will focus on the existing variables monitored under the GDP concept, applying and manipulating them to optimize tissue perfusion in real-time.
体外循环(ECC)是心脏外科手术的重要组成部分,因为它能在心脏骤停期间维持生命支持,这是进行心脏外科干预所必需的。然而,体外循环对局部和全身都有不利影响,因为其成分会改变大循环和微循环,从而可能导致灌注不足。目标导向灌注(GDP)技术旨在根据预先设定的目标对血液动力学进行个性化管理,从而优化 CPB 期间的组织氧合和灌注。这意味着要持续监测关键参数,实时改变灌注策略。在过去的 10 年中,人们探索了使用 GDP 的好处,并将其优于传统方法的优势直观地展现出来。本文旨在介绍 CPB 期间 GDP 监测实践。我们将重点介绍在 GDP 概念下监测的现有变量,应用和操作这些变量以实时优化组织灌注。