Isolation of filamentous basidiomycetes from respiratory samples in a tertiary care Spanish hospital.

IF 1.5 4区 生物学 Q4 MYCOLOGY Revista Iberoamericana De Micologia Pub Date : 2023-10-01 Epub Date: 2024-02-06 DOI:10.1016/j.riam.2023.11.001
Iker Falces-Romero, Inmaculada Quiles-Melero, Julio García-Rodríguez
{"title":"Isolation of filamentous basidiomycetes from respiratory samples in a tertiary care Spanish hospital.","authors":"Iker Falces-Romero, Inmaculada Quiles-Melero, Julio García-Rodríguez","doi":"10.1016/j.riam.2023.11.001","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The clinical significance of the filamentous basidiomycetes isolated from clinical samples is not always clear. Thus, these fungi have been considered environmental contaminants traditionally.</p><p><strong>Aims: </strong>To review those clinical cases in which filamentous basidiomycetes from respiratory samples had been isolated.</p><p><strong>Methods: </strong>The retrospective study was carried out in a single tertiary care hospital. We recovered all culture-confirmed isolations of filamentous basidiomycetes from respiratory samples (bronchial aspirate [BAS], bronchoalveolar lavage [BAL] and sputum) analyzed between the years 2020 and 2023. Isolates were identified by ITS region sequencing.</p><p><strong>Results: </strong>In six patients a filamentous basidiomycete had been isolated from a respiratory sample. The species identified were all different: Fomitopsis sp. (BAS), Trametes ljubarskyi (BAL), Stereum gausapatum (BAS), Porostereum spadiaceum (BAS), Phlebia subserialis (sputum) and Inonotus levis (BAL). All the patients were immunosuppressed or had an underlying disease with pulmonary involvement. None of them received any specific antifungal treatment (in relation with the fungus isolated) and all six improved clinically and were discharged.</p><p><strong>Conclusions: </strong>The isolation of filamentous basidiomycetes in these patients had uncertain clinical significance. However, the isolation of any filamentous basidiomycete in respiratory samples from immunosuppressed patients or patients with chronic pulmonary disease is an emerging situation that should be carefully assessed in the context of chronic allergic episodes or suspicion of invasive fungal infections.</p>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Iberoamericana De Micologia","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.riam.2023.11.001","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/6 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MYCOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: The clinical significance of the filamentous basidiomycetes isolated from clinical samples is not always clear. Thus, these fungi have been considered environmental contaminants traditionally.

Aims: To review those clinical cases in which filamentous basidiomycetes from respiratory samples had been isolated.

Methods: The retrospective study was carried out in a single tertiary care hospital. We recovered all culture-confirmed isolations of filamentous basidiomycetes from respiratory samples (bronchial aspirate [BAS], bronchoalveolar lavage [BAL] and sputum) analyzed between the years 2020 and 2023. Isolates were identified by ITS region sequencing.

Results: In six patients a filamentous basidiomycete had been isolated from a respiratory sample. The species identified were all different: Fomitopsis sp. (BAS), Trametes ljubarskyi (BAL), Stereum gausapatum (BAS), Porostereum spadiaceum (BAS), Phlebia subserialis (sputum) and Inonotus levis (BAL). All the patients were immunosuppressed or had an underlying disease with pulmonary involvement. None of them received any specific antifungal treatment (in relation with the fungus isolated) and all six improved clinically and were discharged.

Conclusions: The isolation of filamentous basidiomycetes in these patients had uncertain clinical significance. However, the isolation of any filamentous basidiomycete in respiratory samples from immunosuppressed patients or patients with chronic pulmonary disease is an emerging situation that should be carefully assessed in the context of chronic allergic episodes or suspicion of invasive fungal infections.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
从西班牙一家三级医院的呼吸道样本中分离出丝状基枝菌。
背景:从临床样本中分离出的丝状基枝真菌的临床意义并不总是很明确。目的:回顾从呼吸道样本中分离出丝状基枝菌的临床病例:回顾性研究在一家三级甲等医院进行。我们从 2020 年至 2023 年期间分析的呼吸道样本(支气管吸出物[BAS]、支气管肺泡灌洗液[BAL]和痰液)中回收了所有经培养证实的丝状基枝菌分离物。通过 ITS 区域测序对分离菌进行鉴定:结果:有六名患者从呼吸道样本中分离出丝状基枝菌。鉴定出的菌种各不相同:Fomitopsis sp. (BAS)、Trametes ljubarskyi (BAL)、Stereum gausapatum (BAS)、Porostereum spadiaceum (BAS)、Phlebia subserialis (痰)和 Inonotus levis (BAL)。所有患者都有免疫抑制或肺部受累的基础疾病。他们都没有接受任何特殊的抗真菌治疗(与分离到的真菌有关),所有六名患者的临床症状均有所改善并痊愈出院:结论:在这些患者中分离出丝状玄拟真菌的临床意义并不确定。然而,从免疫抑制患者或慢性肺部疾病患者的呼吸道样本中分离出任何丝状基霉菌都是一种新情况,在慢性过敏性疾病发作或怀疑有侵袭性真菌感染时应仔细评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
1.90
自引率
0.00%
发文量
17
审稿时长
81 days
期刊介绍: Revista Iberoamericana de Micología (Ibero-American Journal of Mycology) is the official journal of the Asociación Española de Micología, Asociación Venezolana de Micología and Asociación Argentina de Micología (The Spanish, Venezuelan, and Argentinian Mycology Associations). The Journal gives priority to publishing articles on studies associated with fungi and their pathogenic action on humans and animals, as well as any scientific studies on any aspect of mycology. The Journal also publishes, in Spanish and in English, original articles, reviews, mycology forums, editorials, special articles, notes, and letters to the editor, that have previously gone through a scientific peer review process.
期刊最新文献
Clinical response to prednisone in a severe case of infant-juvenile paracoccidioidomycosis Fungemia due to opportunistic fungi in patients with cancer Azole resistance in a clinical isolate of Aspergillus fumigatus from Chile Experimental study of specific and nonspecific blood culture bottles for the diagnosis of candidemia Pneumocystis carinii infection drives upregulation of Fn1 expression that causes pulmonary fibrosis with an inflammatory response
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1