Diet in pediatric inflammatory bowel disease: What to eat and what to avoid?

Ivan D. Milovanovich
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Abstract

Pediatric inflammatory bowel diseases (PIBD) are autoinflammatory, multifactorial diseases that can affect children at any age. There are three types of PIBD: Crohn's disease, ulcerative colitis and unclassified colitis Both genetic and environmental factors are involved in the onset of PIBD. It is suspected that diet composition significantly contributes to IBD risk. On the other hand, in clinical presentation, malnutrition and growth retardation are one of the key signs and they are caused by anorexia and increased metabolism rate. We can say that diet is an important hallmark of PIBD in pathogenesis as well as in the therapy. Exclusive enteral nutrition (EEN) is the most widely used dietary intervention for the treatment of Crohn's disease, but is affected by a low tolerability, especially in pediatric patients. Promising alternative regimens are represented by Crohn's Disease Exclusion Diet (CDED), and other elimination diets, whose use is gradually spreading. The aim of the review is to provide an overview on the latest evidence about the role of nutrition and diet in pediatric IBD.

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小儿炎症性肠病的饮食:吃什么、忌什么?
小儿炎症性肠病(PIBD)是一种自身炎症性、多因素疾病,可影响任何年龄段的儿童。小儿炎症性肠病有三种类型:克罗恩病、溃疡性结肠炎和未分类结肠炎 遗传和环境因素都与小儿炎症性肠病的发病有关。人们怀疑,饮食结构是导致 IBD 风险的重要因素。另一方面,在临床表现上,营养不良和生长迟缓是主要体征之一,它们是由厌食和新陈代谢率增高引起的。可以说,在发病机制和治疗方面,饮食是 PIBD 的一个重要标志。纯肠内营养(EEN)是治疗克罗恩病最广泛使用的饮食干预方法,但其耐受性较差,尤其是在儿童患者中。克罗恩病排除性饮食(CDED)和其他排除性饮食是很有前途的替代方案,其使用范围正在逐渐扩大。本综述旨在概述有关营养和饮食在小儿 IBD 中作用的最新证据。
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Global pediatrics
Global pediatrics Perinatology, Pediatrics and Child Health
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