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Determinants of essential newborn care for institutional births in Bangladesh: Findings from the 2019 MICS Survey
Pub Date : 2025-02-04 DOI: 10.1016/j.gpeds.2025.100246
Syeda Sumaiya Efa , Syed Nafi Mahdee , Md Fuad Al Fidah

Background

Millions of newborns die globally during the neonatal period. Essential newborn care (ENC) is designed to lower neonatal morbidity and mortality. The current study investigated the association between sociodemographic, antenatal, and delivery care factors that may impact ENC practices for institutional birth in Bangladesh.

Methods

The current study utilized publicly available, nationally representative data. A total of 404 participants were considered for analysis. A logistic regression model was developed, with significant variables identified by chi-square tests. A p-value <0.05 was considered statistically significant (α=0.05).

Results

Almost half of the participants were <20 years old (241, 59.7 %), half had secondary level education (205, 50.7 %), and one-third were from the poorest wealth quintile (123, 30.4 %). The prevalence of proper ENC was 57 (14.1 %). In 383 (94.8 %) cases, instruments were utilized to cut the umbilical cord, with 271 (67.1 %) showing no application of substances to the cord stump. Following birth, 396 (98.0 %) newborns underwent drying, while 294 (72.8 %) were immediately wrapped. Delayed bathing was observed in 131 (32.4 %) cases, with 359 (89.9 %) initiating breastfeeding. Proper ENC was associated with assistance by skilled birth attendant (SBA) (p = 0.004) and residence (p = 0.047). Higher odds of proper ENC were found among those who received assistance by SBA (AOR: 2.39; 95 % CI: 1.32–4.32; p = 0.004) and belonging to the middle class (AOR: 2.90; 95 % CI: 1.26–6.68; p-value=0.012).

Conclusion

Proper ENC in institutional birth is not widely practiced in Bangladesh. Targeted health promotional activities and policies, especially assistance by a SBA and raising awareness among mothers of the poorest families, can help to improve ENC practices during institutional birth.
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引用次数: 0
The present and the future of point-of-care ultrasound in Pediatric Care
Pub Date : 2025-02-04 DOI: 10.1016/j.gpeds.2025.100245
G. Bausani , AMC Musolino , L. Reali
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引用次数: 0
Impact and frequency of misdiagnosis of appendicitis in pediatric patients with gastroenteritis in a developing country
Pub Date : 2025-01-16 DOI: 10.1016/j.gpeds.2025.100244
Pastor Escárcega-Fujigaki , Guillermo Hernández-Peredo-Rezk , Gerardo Alonso-Acosta , Keren-Hapuc Vargas-Amador

Aim

Appendicitis manifests with atypical symptoms in a large percentage of patients, leading to diagnostic errors that delay diagnosis. This study aimed to evaluate the impact and frequency of appendicitis being incorrectly diagnosed as gastroenteritis in a developing country.

Methods

This prospective, comparative study included 207 pediatric patients with appendicitis divided into two groups: group A, with 117 (56.5 %) patients with diagnostic errors, and group B, with 90 (43.4 %) patients without diagnostic errors. Clinical, laboratory, and imaging data were compared using the Mann–Whitney tests, odds ratio (OR), and 95 % confidence interval (CI) with statistical significance set at p-value <0.05.

Results

The diagnosis was confused with gastroenteritis in 66 (56.4 %) patients, causing a delay in surgical management, which was statistically significant (OR: 2.25; 95 % CI: 1.23–4.09; p < 0.005) when compared with group B. The second most common cause of confusion was colitis, which was observed in 40 (34.2 %) patients. Group A had a large number of perforated appendicitis cases (OR: 3.22; 95 % CI: 1.81–5.72; p < 0.01), with more days till oral administration initiation (OR: 3.68; 95 % CI: 1.32–10.27; p < 0.01) and longer hospital stays (OR: 6.83; 95 % CI: 1.85–25.11; p < 0.01). Furthermore, general practitioners more frequently had diagnostic errors than pediatricians (OR: 0.17; 95 % CI: 0.07–0.43; p < 0.01).

Conclusions

The diagnosis of appendicitis was confused with gastroenteritis or colitis in majority of pediatric patients. Practitioners should be aware of the possibility of appendicitis in patients presenting with abdominal pain, diarrhea, or fever.

Level of Evidence

III
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引用次数: 0
Cost-effectiveness evaluation of neonatal emergency transport organization in Italy
Pub Date : 2025-01-07 DOI: 10.1016/j.gpeds.2025.100243
Carlo Bellini , Maurizio Gente , Diego Minghetti , Luca A. Ramenghi

Objective

The aim of this study was to evaluate the cost-effectiveness of the Italian Neonatal Emergency Transport Service (NETS), to analyse its current organisation and to identify potential financial benefits from improvements.

Methods

Using data from the 2023 national NETS survey conducted by the Italian Society of Neonatology, regional cost-effectiveness of operating the system were calculated. These were compared with ideal costs for on-call and dedicated NETS models, based on a previously established methodology.

Results

The total cost of operating NETS in Italy was €32,785,650. Of this, €24,964,050 was associated with services organised according to the on-call model, while €7,821,600 was associated with dedicated services. The cost per transport varied considerably between regions. The national median cost for on-call services was €7,386 (ranging from €1,809 to €76,209), while the national median cost for dedicated services was €2,421 (ranging from €2,073 to €2,770). The actual total cost could be reduced to the ideal cost of €15,304,308, with the ideal cost per individual transport being €2,450 for on-call services and €2,250 for dedicated services (compared to the current medians of €7,386 and €2,421, respectively).

Conclusions

The study concluded that the Italian NETS organisation is expensive and unsustainable due to limited financial resources, and requires a complete overhaul. The implementation of a more cost-effective 'hub-and-spoke' NETS network system could significantly improve financial sustainability. The findings suggest that improvements to the NETS organisation are needed not only in Italy, but potentially across Europe.
{"title":"Cost-effectiveness evaluation of neonatal emergency transport organization in Italy","authors":"Carlo Bellini ,&nbsp;Maurizio Gente ,&nbsp;Diego Minghetti ,&nbsp;Luca A. Ramenghi","doi":"10.1016/j.gpeds.2025.100243","DOIUrl":"10.1016/j.gpeds.2025.100243","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to evaluate the cost-effectiveness of the Italian Neonatal Emergency Transport Service (NETS), to analyse its current organisation and to identify potential financial benefits from improvements.</div></div><div><h3>Methods</h3><div>Using data from the 2023 national NETS survey conducted by the Italian Society of Neonatology, regional cost-effectiveness of operating the system were calculated. These were compared with ideal costs for on-call and dedicated NETS models, based on a previously established methodology.</div></div><div><h3>Results</h3><div>The total cost of operating NETS in Italy was €32,785,650. Of this, €24,964,050 was associated with services organised according to the on-call model, while €7,821,600 was associated with dedicated services. The cost per transport varied considerably between regions. The national median cost for on-call services was €7,386 (ranging from €1,809 to €76,209), while the national median cost for dedicated services was €2,421 (ranging from €2,073 to €2,770). The actual total cost could be reduced to the ideal cost of €15,304,308, with the ideal cost per individual transport being €2,450 for on-call services and €2,250 for dedicated services (compared to the current medians of €7,386 and €2,421, respectively).</div></div><div><h3>Conclusions</h3><div>The study concluded that the Italian NETS organisation is expensive and unsustainable due to limited financial resources, and requires a complete overhaul. The implementation of a more cost-effective 'hub-and-spoke' NETS network system could significantly improve financial sustainability. The findings suggest that improvements to the NETS organisation are needed not only in Italy, but potentially across Europe.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100243"},"PeriodicalIF":0.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying birth asphyxia risk factors: Case-control study of new-borns delivered at public health institutions in Gedeo Zone, Ethiopia
Pub Date : 2024-12-31 DOI: 10.1016/j.gpeds.2024.100242
Getachew Mergia , Getnet Melaku

Background

Birth asphyxia, a global health issue causing insufficient oxygen supply, causes around 900,000 annual deaths worldwide. This study aimed to identify risk factors for birth asphyxia in new-borns delivered at public health institutions, reducing neonatal mortality.

Methods

This study used an institution-based, unmatched case-control study design with a total of 354 new-borns. We used descriptive statistics and a logistic regression model to thoroughly evaluate the data and find characteristics linked with birth asphyxia. The data were given using adjusted odds ratios with 95 % confidence intervals to ensure a thorough understanding of the risk variables involved.

Result

The study included 119 cases and 235 controls, with a median maternal age of 27 years. Factors contributing to birth asphyxia included mode of delivery and amniotic fluid color, with caesarean section (AOR: 4.706, 95 % CI: 2.132–10.386) and unclear amniotic fluid (AOR: 4.991, 95 % CI: 2.609–9.547) significantly increasing the odds of asphyxia.

Conclusion

This study identified significant factors contributing to birth asphyxia, including Caesarean section mode of delivery and unclear amniotic fluid color. These findings highlight the importance of monitoring and managing delivery methods and amniotic fluid status to reduce the risk of birth asphyxia.
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引用次数: 0
Newborn birth weight and its associated risk factors in Somalia using Somalia health and demographic survey
Pub Date : 2024-12-27 DOI: 10.1016/j.gpeds.2024.100241
Denekew Bitew Belay , Nigussie Adam Birhan , Mahad Ibrahim Ali , Ding-Geng Chen

Background

Low birth weight is the result of fetal growth and it is a strong sign of infant morbidity and mortality. In sub-Saharan Africa, the number of low birth weight live births is estimated to have increased from 4.4 million in 2000 to 5 million in 2015. Low birth weight is a strong indicator of multifaceted public health problems, including unfavorable socio-demographic conditions, chronic illness, and poor health care during pregnancy. The aim of this study was to assess the prevalence and risk factors of newborn birth weight in Somalia.

Methods

The data used for this study were obtained from the 2020 Somalia Health and Demographic Survey. A sample of 7462 newborn with their birth weight within five years preceding the survey was included. The newborns’ birth weight; which is first categorized in to three: low birth weight (<2.5 kg), normal birth weight (2.5–4 kg) and high birth weight (>4 kg), was considered as a response variable. The analysis was carried out using ordinal logistic regression and adjusted odds ratio with 95 % confidence interval and p-value <0.05 was used to declare statistical significance.

Results

From the total of 7462 newborns include in the study, 1196 (16.03 %), 5304(71.08 %) and 962 (12.89 %) were born with low birth weight, normal birth weight and high birth weight, respectively. Maternal age (AOR = 1.48; 95 %CI: 1.12–1.956), having Antenatal care (ANC) visit (AOR = 1.24; 95 %CI: 1.09–1.41), gestational age 37 weeks (AOR = 2.02; 95 % CI: 1.34–3.03), rich wealth index family (AOR = 1.46; 95 %CI: 1.29–1.65) and mother with secondary/higher educational level (AOR = 1.51; 95 %CI: 1.19–1.92) as well as place of residence were significantly associated with higher birth weight.

Conclusion

The results of this study showed that birth weight is significantly associated with mother age, ANC visit, mother educational level, wealth index, residence, and gestational age at birth. Significantly large proportions of newborn babies are born with low-birth weight and this might be duet to many factors. Since low birth weight is a strong indicator of multifaceted public health problem, the governmental and non- governmental organizations working on maternal health should focus on alleviating this public health burden by giving special attention for antenatal care utilization coverage and improve other maternal health.
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引用次数: 0
Impact of surgical treatment on neonatal management in extremely low birth weight infants: Single-center retrospective study
Pub Date : 2024-12-23 DOI: 10.1016/j.gpeds.2024.100240
Seiichiro Inoue, Yuki Muta, Yuta Takeuchi, Kohei Kawaguchi, Akio Odaka

Background

Few studies have examined the details of extremely low birth weight (ELBW) infants (i.e., infants with a birth weight < 1000 g) on neonatal intensive care units (NICUs) who require surgical treatment. Therefore, we analyzed mortality, morbidity, and clinical variables in ELBW infants who received surgical treatments at our center from 2009 to 2022.

Methods

All ELBW infants were included who received surgical treatment at our NICU from January 2009 to December 2022. We compared data from infants treated in the early (2009–2015) and late (2016–2022) periods and investigated trends in mortality, morbidity, and clinical variables.

Results

A total of 678 ELBW infants were admitted and cared at our neonatal center and 56 ELBW infants were received surgical treatment. The number of patients who received surgical treatment increased in the late period (10.4 % (36/345)) compared to the early period (6.33 % (20/316)) (early vs late period: p = 0.0398). The indications for surgery were expanded in late period compared to early periods. In the late period, the survival rate was higher (63.5 vs 75.0 %: early vs late period). No statistical difference was observed between the early and late period in the duration of the NICU stay. However, the duration of NICU stay in died patients were shorter compared to the survived patients (median (lower -upper quartiles):196.5 (166.75–261.25 vs 75.0 (49.0–183.5): early vs late period). The total number of surgical treatments which each patient received were higher in survived cases (median (lower -upper quartiles): 2.0 (2.0–4.0) vs 1.0 (1.0–2.0): survived vs died cases: p = 0.013).

Conclusions

Recent advances in NICU care have expanded the indications for surgical treatment in ELBW infants. Survival rates appear to have improved. In more recent years, patients have increasingly undergone multi-step surgical treatment, which we consider to be a result of the improved the systemic status of infants in perioperative period.

Level of evidence

3
{"title":"Impact of surgical treatment on neonatal management in extremely low birth weight infants: Single-center retrospective study","authors":"Seiichiro Inoue,&nbsp;Yuki Muta,&nbsp;Yuta Takeuchi,&nbsp;Kohei Kawaguchi,&nbsp;Akio Odaka","doi":"10.1016/j.gpeds.2024.100240","DOIUrl":"10.1016/j.gpeds.2024.100240","url":null,"abstract":"<div><h3>Background</h3><div>Few studies have examined the details of extremely low birth weight (ELBW) infants (i.e., infants with a birth weight &lt; 1000 g) on neonatal intensive care units (NICUs) who require surgical treatment. Therefore, we analyzed mortality, morbidity, and clinical variables in ELBW infants who received surgical treatments at our center from 2009 to 2022.</div></div><div><h3>Methods</h3><div>All ELBW infants were included who received surgical treatment at our NICU from January 2009 to December 2022. We compared data from infants treated in the early (2009–2015) and late (2016–2022) periods and investigated trends in mortality, morbidity, and clinical variables.</div></div><div><h3>Results</h3><div>A total of 678 ELBW infants were admitted and cared at our neonatal center and 56 ELBW infants were received surgical treatment. The number of patients who received surgical treatment increased in the late period (10.4 % (36/345)) compared to the early period (6.33 % (20/316)) (early vs late period: <em>p</em> = 0.0398). The indications for surgery were expanded in late period compared to early periods. In the late period, the survival rate was higher (63.5 vs 75.0 %: early vs late period). No statistical difference was observed between the early and late period in the duration of the NICU stay. However, the duration of NICU stay in died patients were shorter compared to the survived patients (median (lower -upper quartiles):196.5 (166.75–261.25 vs 75.0 (49.0–183.5): early vs late period). The total number of surgical treatments which each patient received were higher in survived cases (median (lower -upper quartiles): 2.0 (2.0–4.0) vs 1.0 (1.0–2.0): survived vs died cases: <em>p</em> = 0.013).</div></div><div><h3>Conclusions</h3><div>Recent advances in NICU care have expanded the indications for surgical treatment in ELBW infants. Survival rates appear to have improved. In more recent years, patients have increasingly undergone multi-step surgical treatment, which we consider to be a result of the improved the systemic status of infants in perioperative period.</div></div><div><h3>Level of evidence</h3><div>3</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100240"},"PeriodicalIF":0.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Turkish Neonatal Society position paper for stem cell therapy in neonates
Pub Date : 2024-12-21 DOI: 10.1016/j.gpeds.2024.100239
Merih Cetinkaya , Esin Koc , Betul Acunas , Mete Akisu , Saadet Arsan , Fuat Emre Canpolat , Dilek Dilli , Zeynep Ince , Nilgun Koksal , Abdullah Kumral , Eren Ozek , Hasan Ozkan , Ayse Korkmaz Toygar , Sule Yigit , Aysegul Zenciroglu , Mehmet Vural
Stem cell (SC) therapy has been proposed as a promising therapeutic modality in neonatology, especially for prevention and/or treatment of several interactable diseases such as bronchopulmonary dysplasia, intraventricular hemorrhage, hypoxic-ischemic encephalopathy and others. However, there are several uncertainities in terms of indications, timing, dosage, and safety of SC therapy for routine clinical use in neonates. Herein, a group of Turkish Neonatal Society members evaluated the systematic reviews, meta-analyses, clinical and experimental studies and also case-reports in the literature about the usage of SC therapy in neonatal diseases.
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引用次数: 0
Right side Bochdalek's hernia with right herniated thoracic renal ectopia: A case report and review of literature
Pub Date : 2024-12-13 DOI: 10.1016/j.gpeds.2024.100238
Osias Tilahun Merga, Nebiyou Simegnew Bayleyegn

Introduction and importance

Congenital diaphragmatic hernia is an uncommon defect of the diaphragm that can cause the abdominal contents to herniate into the chest cavity, putting the newborn at risk for complications with the heart and lungs. The spectrum of congenital diaphragmatic hernia disease can include acute respiratory failure that manifests as neonatal death, as well as asymptomatic problems that are not detected during the neonatal era.

Case presentation

A 6 kilogram, 4-month-old baby had been breathing rapidly for two weeks. According to the mother, he has also had breastfeeding interruption, dry intermittent cough, and high-grade intermittent fever. Meanwhile, the patient was diagnosed with severe acute malnutrition, severe pneumonia, and a congenital diaphragmatic hernia complicated with Intrathoracic ectopic kidney. He was admitted to pediatric ward and managed with intravenous antibiotics, intranasal oxygen and Formula-75 for two weeks.

Clinical discussion

Congenital diaphragmatic hernia is a rare kind of congenital surgical problem. The diaphragm fails to close during embryonic development, leading to intrathoracic abdominal viscera herniation, as well as variable degrees of pulmonary hypoplasia, pulmonary hypertension, and heart failure at birth. Intrathoracic ectopic kidneys are exceptionally rare. They represent only <5 % of renal ectopia. The prognosis for early presenters in high-income nations has improved because of advancements in newborn care; nevertheless, in Africa, the situation is still dire.

Conclusion

Congenital diaphragmatic hernias with Intrathoracic ectopic kidneys are exceptionally rare. Compared to congenital diaphragmatic hernias linked to other abnormalities or syndromes, isolated congenital diaphragmatic hernias have a higher survival rate.
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引用次数: 0
Sleep disturbances in hospitalized children: Comparison between acute admission and regular care units
Pub Date : 2024-12-10 DOI: 10.1016/j.gpeds.2024.100237
Pia Burger , Lindsay M.H. Steur , Jorinde A.W. Polderman , Reinoud J.B.J. Gemke

Introduction

Hospitalization adversely affects children's sleep, primary due to disease-, staff-, psychosocial- and environment-related factors. Clustering discontinuity in Acute Admission Units (AAU's) appears to enhance efficiency in clinical care. However, sleep may be more affected in a pediatric AAU as compared to regular care units (RCUs).

Methods

In children of 1–12 years of age admitted to the AAU or RCUs, we used actigraphy to observe sleep, assessing Total Sleep Time (TST), Sleep Onset Latency (SOL), Wake After Sleep Onset (WASO), sleep efficiency, and awakenings. Subjective sleep quality was evaluated with PROMIS questionnaires. Sleep disturbances due to disease-, staff-, patient-, environment-, treatment-related factors were examined and compared between wards.

Results

Significant differences were observed between the AAU and RCUs in terms of specialty type and admission reasons: surgical patients and exacerbations of chronic diseases were more often admitted to RCUs. No significant differences were found between AAU and RCUs regarding TST (497 (92) (mean (SD)) vs 476 (96)), and WASO (113 (74) in both the AAU and RCU's). There was a trend towards more staff-related disturbances in the AAU (67 % vs 56 % p = 0.07, specifically regarding waking (32 % vs 22 %, p = 0.07). In all wards, sleep disturbances were reported by approximately 93 % of the patients.

Conclusion

Despite the concentration of clinical discontinuity to enhance efficiency of care in a novel pediatric AAU, no differences with regards to sleep (disturbances) were observed in comparison to the RCUs. Yet substantial sleep disturbances in both settings indicate the need for targeted interventions to improve inpatient sleep.
{"title":"Sleep disturbances in hospitalized children: Comparison between acute admission and regular care units","authors":"Pia Burger ,&nbsp;Lindsay M.H. Steur ,&nbsp;Jorinde A.W. Polderman ,&nbsp;Reinoud J.B.J. Gemke","doi":"10.1016/j.gpeds.2024.100237","DOIUrl":"10.1016/j.gpeds.2024.100237","url":null,"abstract":"<div><h3>Introduction</h3><div>Hospitalization adversely affects children's sleep, primary due to disease-, staff-, psychosocial- and environment-related factors. Clustering discontinuity in Acute Admission Units (AAU's) appears to enhance efficiency in clinical care. However, sleep may be more affected in a pediatric AAU as compared to regular care units (RCUs).</div></div><div><h3>Methods</h3><div>In children of 1–12 years of age admitted to the AAU or RCUs, we used actigraphy to observe sleep, assessing Total Sleep Time (TST), Sleep Onset Latency (SOL), Wake After Sleep Onset (WASO), sleep efficiency, and awakenings. Subjective sleep quality was evaluated with PROMIS questionnaires. Sleep disturbances due to disease-, staff-, patient-, environment-, treatment-related factors were examined and compared between wards.</div></div><div><h3>Results</h3><div>Significant differences were observed between the AAU and RCUs in terms of specialty type and admission reasons: surgical patients and exacerbations of chronic diseases were more often admitted to RCUs. No significant differences were found between AAU and RCUs regarding TST (497 (92) (mean (SD)) vs 476 (96)), and WASO (113 (74) in both the AAU and RCU's). There was a trend towards more staff-related disturbances in the AAU (67 % vs 56 % <em>p</em> = 0.07, specifically regarding waking (32 % vs 22 %, <em>p</em> = 0.07). In all wards, sleep disturbances were reported by approximately 93 % of the patients.</div></div><div><h3>Conclusion</h3><div>Despite the concentration of clinical discontinuity to enhance efficiency of care in a novel pediatric AAU, no differences with regards to sleep (disturbances) were observed in comparison to the RCUs. Yet substantial sleep disturbances in both settings indicate the need for targeted interventions to improve inpatient sleep.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100237"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Global pediatrics
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