{"title":"Use of botulinum toxin type A in the prehabilitation of abdominal wall musculature for hernia repair: a consensus proposal","authors":"","doi":"10.1016/j.cireng.2023.12.003","DOIUrl":null,"url":null,"abstract":"<div><p>The prehabilitation of the abdominal wall through the infiltration of botulinum toxin type A, which induces temporary chemical denervation (\"chemical component separation\") in the lateral abdominal musculature, is a common practice in units specialized in abdominal wall surgery. However, its use for this indication is currently off-label.</p><p>The main objective of this article is to describe a consensus proposal regarding indications, contraindications, dosages employed, potential side effects, administration method, and measurement of possible outcomes. Additionally, a proposal for an informed consent document endorsed by the Abdominal Wall Section of the Spanish Association of Surgeons is attached.</p></div>","PeriodicalId":93935,"journal":{"name":"Cirugia espanola","volume":"102 7","pages":"Pages 391-399"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cirugia espanola","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2173507724000462","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The prehabilitation of the abdominal wall through the infiltration of botulinum toxin type A, which induces temporary chemical denervation ("chemical component separation") in the lateral abdominal musculature, is a common practice in units specialized in abdominal wall surgery. However, its use for this indication is currently off-label.
The main objective of this article is to describe a consensus proposal regarding indications, contraindications, dosages employed, potential side effects, administration method, and measurement of possible outcomes. Additionally, a proposal for an informed consent document endorsed by the Abdominal Wall Section of the Spanish Association of Surgeons is attached.
A 型肉毒毒素可诱导侧腹肌肉组织暂时性化学去神经支配（"化学成分分离"），通过这种方法对腹壁进行预康复治疗，是腹壁外科专科的常见做法。然而，目前将其用于这一适应症还属于非标签使用。本文的主要目的是就适应症、禁忌症、使用剂量、潜在副作用、给药方法和可能结果的测量等方面描述一项共识提案。此外，本文还附有西班牙外科医生协会腹壁分会认可的知情同意书建议。
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