Pitfalls in Urinary Tract Cytopathology.

IF 1.6 4区 医学 Q3 PATHOLOGY Acta Cytologica Pub Date : 2024-01-01 Epub Date: 2024-02-13 DOI:10.1159/000537737
Mahmoud A Hashim, Asma Arshia, Shafi Rehman, Ashish Chandra
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Abstract

Background: Urine cytopathology is a cost-effective method to diagnose and follow patients with high-grade urothelial carcinoma (UC). However, some benign, reactive, and metaplastic changes may mimic UC and pose a diagnostic challenge for cytopathologists.

Summary: Our comprehensive review focuses on summarizing common pitfalls encountered in urine cytopathology, based on the 2nd edition of The Paris System (TPS) for reporting urinary tract cytopathology and other recent published literature. These pitfalls include urothelial tissue fragments, degenerative changes, treatment effects, viral cytopathic changes, iatrogenic and metaplastic changes. Our aim was to provide a clear understanding of these mimics in order to avoid diagnostic errors.

Key message: It is crucial for cytopathologists to recognize benign, reactive, or metaplastic lesions that sometimes resemble UC. An awareness of these cytological changes is essential to make an accurate diagnosis.

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尿路细胞病理学中的陷阱。
尿液细胞病理学是诊断和跟踪高级别尿路上皮癌(HGUC)患者的一种经济有效的方法。然而,一些良性、反应性和变性病变可能会模仿 HGUC,给细胞病理学家的诊断带来挑战。摘要:我们的综合综述重点总结了尿液细胞病理学中常见的误区,主要是基于资深作者(AC)的经验,利用第二版《巴黎系统》(TPS)中描述的诊断标准报告尿路细胞病理学和近期发表的文献。这些标准包括尿道组织碎片、器械样本、退行性病变、治疗效果、病毒性细胞病变、先天性病变和变性病变。我们的目的是提供对这些挑战的清晰认识,以协助细胞病理学家做出准确诊断。关键信息:对于细胞病理学家来说,识别可能与 HGUC 相似的良性、反应性和变性病变至关重要。了解这些细胞学特征对于减少诊断错误至关重要。
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来源期刊
Acta Cytologica
Acta Cytologica 生物-病理学
CiteScore
3.70
自引率
11.10%
发文量
46
审稿时长
4-8 weeks
期刊介绍: With articles offering an excellent balance between clinical cytology and cytopathology, ''Acta Cytologica'' fosters the understanding of the pathogenetic mechanisms behind cytomorphology and thus facilitates the translation of frontline research into clinical practice. As the official journal of the International Academy of Cytology and affiliated to over 50 national cytology societies around the world, ''Acta Cytologica'' evaluates new and existing diagnostic applications of scientific advances as well as their clinical correlations. Original papers, review articles, meta-analyses, novel insights from clinical practice, and letters to the editor cover topics from diagnostic cytopathology, gynecologic and non-gynecologic cytopathology to fine needle aspiration, molecular techniques and their diagnostic applications. As the perfect reference for practical use, ''Acta Cytologica'' addresses a multidisciplinary audience practicing clinical cytopathology, cell biology, oncology, interventional radiology, otorhinolaryngology, gastroenterology, urology, pulmonology and preventive medicine.
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