Three-dimensional ultrasound fusion imaging in precise needle placement for thermal ablation of hepatocellular carcinoma.

IF 3 3区 医学 Q2 ONCOLOGY International Journal of Hyperthermia Pub Date : 2024-01-01 Epub Date: 2024-02-15 DOI:10.1080/02656736.2024.2316097
Jiaming Liu, Yuqing Guo, Yueting Sun, Ming Liu, Xiaoer Zhang, Ruiying Zheng, Longfei Cong, Baoxian Liu, Xiaoyan Xie, Guangliang Huang
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Abstract

Purpose: To investigate the value of three-dimensional ultrasound fusion imaging (3DUS FI) technique for guiding needle placement in hepatocellular carcinoma (HCC) thermal ablation.

Methods: A total of 57 patients with 60 HCCs with 3DUS FI-guided thermal ablation were retrospectively included in the study. 3DUS volume data of liver were acquired preoperatively by freehand scanning with the tumor and predetermined 5 mm ablative margin automatically segmented. Plan of needle placement was made through a predetermined simulated ablation zone to ensure a 5 mm ablative margin with the coverage rate toward tumor and ablative margin. With real-time ultrasound and 3DUS fusion imaging, ablation needles were placed according to the plan. After ablation, the ablative margin was immediately evaluated by contrast-enhanced ultrasound and 3DUS fusion imaging. The rate of adequate ablative margin, complete response (CR), local tumor progression (LTP), disease-free survival (DFS), and overall survival (OS) was evaluated.

Results: According to postoperative contrast-enhanced CT or MR imaging, the complete response rate was 100% (60/60), and 83% of tumors (30/36) achieved adequate ablative margin (>5 mm) three-dimensionally. During the follow-up period of 6.0-42.6 months, LTP occurred in 5 lesions, with 1- and 2-year LTP rates being 7.0% and 9.4%. The 1- and 2-year DFS rates were 76.1% and 65.6%, and 1- and 2-year OS rates were 98.1% and 94.0%. No major complications or ablation-related deaths were observed in any patients.

Conclusions: Three-dimensional ultrasound fusion imaging technique may improve the needle placement of thermal ablation for HCC and reduce the rate of LTP.

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三维超声融合成像在肝细胞癌热消融术中的精确置针。
目的:探讨三维超声融合成像(3DUS FI)技术在肝细胞癌(HCC)热消融术中引导穿刺针置入的价值:研究回顾性地纳入了57例60个HCC患者,这些患者均在3DUS FI引导下接受了热消融术。术前通过自由扫描获取肝脏的三维超声体积数据,并自动分割肿瘤和预定的 5 毫米消融边缘。通过预先确定的模拟消融区制定进针计划,以确保 5 毫米的消融边缘,并确保肿瘤和消融边缘的覆盖率。通过实时超声和 3DUS 融合成像,消融针按计划放置。消融后,立即通过对比增强超声和三维超声融合成像对消融边缘进行评估。结果:根据术后对比增强CT或MR成像结果,完全反应率为100%(60/60),83%的肿瘤(30/36)三维达到了足够的消融边缘(>5毫米)。在6.0-42.6个月的随访期间,5个病灶发生了LTP,1年和2年LTP率分别为7.0%和9.4%。1年和2年的DFS率分别为76.1%和65.6%,1年和2年的OS率分别为98.1%和94.0%。所有患者均未出现重大并发症或与消融相关的死亡:结论:三维超声融合成像技术可改善 HCC 热消融的进针位置,降低 LTP 发生率。
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来源期刊
CiteScore
5.90
自引率
12.90%
发文量
153
审稿时长
6-12 weeks
期刊介绍: The International Journal of Hyperthermia
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