"Indole-gence" for the mind.

Jordi Mayneris-Perxachs, Anna Castells-Nobau, José Manuel Fernández-Real
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Abstract

Surging depression rates highlight the need for innovative strategies beyond the traditional focus on the brain. In this issue of Cell Host & Microbe, Cheng et al. uncover a role for the gut microbiota in depression through the intestinal receptor Grp35 and indole pathway, offering hope in fighting against depression.

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心灵的 "吲哚-良药"。
抑郁症发病率的激增凸显出,除了传统的关注大脑之外,还需要创新的策略。在本期《细胞宿主与微生物》(Cell Host & Microbe)杂志上,Cheng 等人通过肠道受体 Grp35 和吲哚途径发现了肠道微生物群在抑郁症中的作用,为抗击抑郁症带来了希望。
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