Management of Wet Age-Related Macular Degeneration: A Case Report

Retno Tharra Handayani, H. A.K Ansyori, Ramzi Amin
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Abstract

Introduction: Age-related macular degeneration (AMD) is a progressive neurodegenerative disease of the photoreceptors and retinal pigment epithelium (RPE). It is a leading cause of blindness and visual impairment in the elderly population, despite recent advances in treatment. We reported a case of wet AMD and its management. Case Presentation: A 69 years old woman complained of blurred vision, especially in the left eye, which she had experienced since 3 years ago, progressively worsen since the last 3 months. Fundoscopy and OCT examination was done. Fundoscopy found no foveal reflex with a drusen and perifoveal haemorrhage found on left eye. She was diagnosed with wet age-related macular degeneration type II of left eye. She had done intravitreal anti-VEGF injection with local anaesthesia. Conclusion: AMD management relies heavily on observation, lifestyle changes, frequent follow-up evaluations, early recognition of visual impairment and detection of CNV. Meanwhile, the current modality for wet AMD therapy is intravitreal anti-VEGF injection to preserve patient’s visual acuity and improve quality of life.
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湿性老年性黄斑变性的治疗:病例报告
简介老年性黄斑变性(AMD)是一种光感受器和视网膜色素上皮(RPE)的进行性神经退行性疾病。尽管近年来治疗手段不断进步,但它仍是老年人失明和视力受损的主要原因。我们报告了一例湿性老年黄斑变性及其治疗。病例介绍:一名 69 岁的妇女主诉视力模糊,尤其是左眼,自 3 年前开始出现这种症状,近 3 个月来逐渐加重。她接受了眼底镜检查和光学视网膜扫描(OCT)检查。眼底镜检查发现没有眼窝反射,左眼有眼底出血。她被诊断为左眼湿性老年性黄斑变性 II 型。她在局部麻醉下进行了玻璃体内抗血管内皮生长因子注射。结论老年黄斑变性的治疗主要依靠观察、改变生活方式、频繁的随访评估、早期识别视力损伤和检测 CNV。同时,目前治疗湿性老年黄斑变性的方法是进行玻璃体内抗血管内皮生长因子注射,以保持患者的视力并提高生活质量。
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