The Sublimate Production Cohort of the Siberian Chemical Plant (Dosimetric Characteristics)

Abstract

Introduction: Uranium, which is the raw material basis of the nuclear industry, is capable of causing adverse medical and biological consequences for workers who come into contact with its compounds in the course of their professional activities. In order to study this effect and to study in detail the biomedical consequences of the effects of uranium compounds on the body of personnel of nuclear power facilities, it is necessary to form a cohort of persons engaged in work with uranium compounds. One of the key elements of the uranium conversion technology carried out within the framework of sublimation production is the production of raw uranium hexafluoride for subsequent isotopic enrichment. Purpose: To form and characterize a cohort of sublimate production of the personnel of the Siberian Chemical Plant involved in work with uranium compounds in the period 1953–2000. Material and methods: The source of information was the regional medical dosimetric register of Seversk Biophysical Research Center, containing information on all current and former employees of the Siberian Chemical Plant (about 65,000 people) from the moment of the company’s foundation to the present. Results: A cohort of Siberian Chemical Plant workers involved in work with uranium compounds in the period 1953–2000 has been formed and described. The cohort consists of 577 people (475 men and 102 women). Biomedical information and dosimetric information about the employees included in the cohort are included in the created database of the personnel of the Siberian Chemical Plant involved in working with uranium compounds in the period 1953–2000. Conclusion: The formed cohort and database will allow conducting epidemiological studies to assess the morbidity and mortality of personnel due to malignant neoplasms, as well as making scientifically sound conclusions about the role of uranium compounds in the occurrence and mortality due to malignant neoplasms.