Investigation of the Effect of Coconut Palm Sugar on Metabolic Disorders in Experimental Diabetic Rats

Q4 Pharmacology, Toxicology and Pharmaceutics Journal of Natural Remedies Pub Date : 2024-02-01 DOI:10.18311/jnr/2024/35036
Shraddha Patel, Archana Navale
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Abstract

Diabetes is a metabolic disorder with many different underlying factors. Humans can develop Type 1 diabetes, which is brought on when the immune system assaults and destroys insulin, and Type 2 diabetes, which can be brought on by several variables, the most important of which is lifestyle, as well as by different genotypes. Due to the presence of polyphenols, which have high antioxidant qualities, Coconut Palm Sugar (CPS) is nutritious and has a good potential for managing diabetes. In this investigation, we took the STZ-Nicotinamide model for diabetes induction. In normal rats (Phase 1) and diabetes-induced rats (Phase 2), After exposure to table sugar and coconut palm sugar, we measured a variety of factors, including body weight, food intake, water consumption, blood sugar level, insulin level, insulin resistance, lipid profile, atherogenic index, and insulin resistance.
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椰子棕糖对实验性糖尿病大鼠代谢紊乱的影响研究
糖尿病是一种代谢紊乱疾病,有许多不同的潜在因素。人类可能患上 1 型糖尿病,这是由免疫系统攻击和破坏胰岛素引起的;也可能患上 2 型糖尿病,这是由几个变量引起的,其中最重要的是生活方式以及不同的基因型。由于椰子多酚具有很高的抗氧化性,椰子棕糖(CPS)不仅营养丰富,而且具有控制糖尿病的良好潜力。在这项研究中,我们采用 STZ-烟酰胺模型诱导糖尿病。在正常大鼠(第一阶段)和糖尿病诱导大鼠(第二阶段)暴露于食糖和椰子糖后,我们测量了各种因素,包括体重、食物摄入量、饮水量、血糖水平、胰岛素水平、胰岛素抵抗、血脂谱、动脉粥样硬化指数和胰岛素抵抗。
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来源期刊
Journal of Natural Remedies
Journal of Natural Remedies Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
0.40
自引率
0.00%
发文量
27
期刊介绍: Nature can provide all the remedies, for all. All substances produced by nature can be recognized; all cells talk the same language as we all are from the same mother cell. Journal of Natural Remedies is devoted toward the understandings of all remedies from nature. Journal of Natural Remedies publishes original articles related to utilisation of any natural source for remedy including bioactive natural products. Studies related to the resources, chemistry (including analytical), biological activity, biotechnology and pharmacology (including toxicology) of archaea, bacteria, protistas, fungi, plants, animals, viruses and minerals fall within the journal’s scope.
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