Haematological Insight: An Epidemiological Study on Prevalence of Anaemia in Diverse Blood Groups within the Population of Hyderabad Sindh

Syed Farhanuddin, Ahmed Hussain Suhag, Habib-ur-Rahman Chohan, Kiran Waheed, J. Warsi, Bilal Atique Arain, Syed Zain Ul Abdeen
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Abstract

dietary deficiencies, which is defined by the WHO as low Haemoglobin levels and low red cell death due to a deficiency of iron in the body. This is especially true for lower socioeconomic groups because of cultural influences and a lack of resources. All genders and age groups are affected by iron deficiency anemia (IDA), which can cause microcytic and hypochromic disease with a range of clinical consequences. According to many recent studies, there may be a connection between blood types and IDA, with those who belong to blood groups O and B perhaps at higher risk of developing the anemia. Confirmation of these links and comprehension of the underlying mechanisms need more study. Materials and Methods: This was a cross-sectional study, conducted at the emergency department of Liaquat University Hospital from June to August 2022 that involved 400 patients who were divided into two groups: a control group comprising 285 patients who were not suffering from iron deficiency anaemia and a study group comprising 415 patients suffering from iron deficiency anemia excluding those with other diseases. A formal consent preceded comprehensive clinical examinations, including blood pressure, pulse rate, and oxygen saturation measurements. Blood group determination employed the glass slide agglutination method, distinguishing A, B, AB, and O groups. Haemoglobin levels were assessed using Sahli's hemoglobinometer, while the complete blood picture was obtained by the blood CP report of the hospital laboratory. Statistical analyses, including Fischer's exact test, were performed using GraphPad 9 prism. Specificity/sensitivity, likelihood ratios, and odds ratios were calculated for further analysis. Conclusion: This study shows a significant relationship between various blood groups and the prevalence of anaemia in the population.
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血液透视:关于海得拉巴信德省不同血型人群贫血患病率的流行病学研究
饮食缺乏症,世界卫生组织将其定义为因体内缺铁导致的血红蛋白水平低和红细胞死亡。由于文化影响和资源匮乏,社会经济地位较低的群体尤其如此。所有性别和年龄组都会受到缺铁性贫血(IDA)的影响,缺铁性贫血可导致小红细胞和低色素性疾病,并造成一系列临床后果。根据最近的许多研究,血型与 IDA 之间可能存在联系,血型为 O 型和 B 型的人患贫血的风险可能更高。对这些联系的确认和对潜在机制的理解还需要更多的研究。材料和方法:这是一项横断面研究,于 2022 年 6 月至 8 月在利亚卡特大学医院急诊科进行,共有 400 名患者参与,分为两组:对照组(包括 285 名非缺铁性贫血患者)和研究组(包括 415 名缺铁性贫血患者,不包括患有其他疾病的患者)。在获得正式同意后进行全面的临床检查,包括测量血压、脉搏和血氧饱和度。血型测定采用玻璃片凝集法,可区分 A、B、AB 和 O 血型。血红蛋白水平使用 Sahli 血红蛋白仪进行评估,全血象则通过医院实验室的血液 CP 报告获得。使用 GraphPad 9 prism 进行统计分析,包括费舍尔精确检验。计算了特异性/敏感性、似然比和几率,以便进一步分析。结论这项研究表明,各种血型与人群中的贫血症患病率之间存在明显关系。
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