Herbal and dietary supplement induced liver injury leading to hepatitis‐associated severe aplastic anemia: A case report

JPGN reports Pub Date : 2024-02-12 DOI:10.1002/jpr3.12041
R. Mercedes, S. Harpavat, Paula M. Hertel, Ghadir Sasa, Susan Kirk, Kalyani Patel, K. Mysore
{"title":"Herbal and dietary supplement induced liver injury leading to hepatitis‐associated severe aplastic anemia: A case report","authors":"R. Mercedes, S. Harpavat, Paula M. Hertel, Ghadir Sasa, Susan Kirk, Kalyani Patel, K. Mysore","doi":"10.1002/jpr3.12041","DOIUrl":null,"url":null,"abstract":"Herbal and dietary supplements (HDS) are a common etiology of drug induced liver injury and, specifically, Herbalife® supplements have been implicated. Hepatitis associated aplastic anemia (HAAA) is a rare and potentially fatal complication after acute hepatitis characterized by pancytopenia. While there have been rare cases of HDS leading to HAAA, no cases of Herbalife® induced liver injury leading to HAAA have been reported from this specific HDS. We report a unique case of severe aplastic anemia developing after sub‐fulminant liver failure associated with chronic HDS use. This case illustrates the importance of warning the public about HDS as their use continues to increase. It is not only important to recognize HDS as etiology, but also for healthcare providers to carefully monitor these patients after resolution of liver injury for the development of HAAA.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"151 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JPGN reports","FirstCategoryId":"0","ListUrlMain":"https://doi.org/10.1002/jpr3.12041","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Herbal and dietary supplements (HDS) are a common etiology of drug induced liver injury and, specifically, Herbalife® supplements have been implicated. Hepatitis associated aplastic anemia (HAAA) is a rare and potentially fatal complication after acute hepatitis characterized by pancytopenia. While there have been rare cases of HDS leading to HAAA, no cases of Herbalife® induced liver injury leading to HAAA have been reported from this specific HDS. We report a unique case of severe aplastic anemia developing after sub‐fulminant liver failure associated with chronic HDS use. This case illustrates the importance of warning the public about HDS as their use continues to increase. It is not only important to recognize HDS as etiology, but also for healthcare providers to carefully monitor these patients after resolution of liver injury for the development of HAAA.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
草药和膳食补充剂诱发肝损伤,导致肝炎相关性重型再生障碍性贫血:病例报告
草药和膳食补充剂(HDS)是药物性肝损伤的常见病因,特别是康宝莱®保健品与此有牵连。肝炎相关性再生障碍性贫血(HAAA)是急性肝炎后的一种罕见且可能致命的并发症,其特征是全血细胞减少。雖然有罕見的HDS導致再生不良性貧血的病例,但尚未有康寶萊®誘發肝損傷導致再生不良性貧血的病例報告。我們報告了一例因長期服用HDS而導致肝衰竭的病例。该病例说明,随着 HDS 使用量的不断增加,向公众发出有关 HDS 的警告非常重要。医护人员不仅要认识到 HDS 是病因,还要在肝损伤缓解后仔细监测这些患者,以防发生 HAAA。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
A novel variant BCL11B mutation in a pediatric patient with difficult-to-treat eosinophilic esophagitis. Identifying parentally perceived barriers for children with celiac disease to participate in elementary school meal programs. Meckel's diverticulum: A challenging diagnosis. Role of gastric ultrasound in pediatric Menetrier's disease: Report of two cases. Extrahepatic biliary atresia and normal-range serum gamma-glutamyltranspeptidase activity: A case report.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1