Are Hospital Admissions (Costs) and Mortality Rate Impacted by Guideline-driven Treatment of Heart Failure?: A Comparison between Participants in the “CorBene” CMP and Standard-care Patients on the Basis of Propensity Score Matching

Josef Ehling, Hans Jürgen Noblé, Detlef Gysan, Mareike Möller, Franz Goss, Winfried Haerer, Simon Glück, Paul Martin Bansmann
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Abstract

Heart failure (HF) is one of the most common diagnoses on admission to hospital in Germany, and one which incurs high costs. Integrated care in case management programs (CMPs) aims to improve treatment quality in the sense of guideline-driven treatment, while reducing hospital admissions, hospital costs, and mortality. A total of 1,844 patient data records from 11 German statutory health insurance companies enrolled in the CMP (intervention group [IG]) were compared with 1,844 standard-care patients (control group) using propensity score matching. The two groups were assessed over three follow-up observation periods regarding the endpoints' treatment costs, hospitalization rate, indicators for treatment quality (diagnostics, physician contact), and mortality. The evaluation revealed no significant differences regarding overall costs. The IG incurred significantly higher outpatient costs, but the medication costs and inpatient costs were not significantly different. There were also no significant differences in the number of hospital admissions. Patients within the CMP had significantly more frequent contact with a cardiologist, and underwent echocardiographic examination significantly more frequently. Mortality during the first follow-up observation year was considerably more favorable for the IG. There are indications that treatment quality is improved in HF patients.
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指导原则驱动的心力衰竭治疗会影响入院率(成本)和死亡率吗?基于倾向得分匹配的 "CorBene "CMP参与者与标准护理患者之间的比较
在德国,心力衰竭(HF)是最常见的入院诊断之一,也是费用较高的一种疾病。病例管理项目(CMPs)中的综合护理旨在提高指南驱动治疗的治疗质量,同时降低入院率、住院费用和死亡率。我们采用倾向得分匹配法,将来自德国 11 家法定医疗保险公司的 1844 份参加病例管理计划的患者数据记录(干预组 [IG])与 1844 份标准护理患者数据记录(对照组)进行了比较。在三个随访观察期内,对两组患者的治疗费用、住院率、治疗质量指标(诊断、医生联系)和死亡率等终点进行了评估。评估结果显示,两组在总费用方面没有明显差异。IG 的门诊费用明显较高,但药物费用和住院费用没有显著差异。入院次数也无明显差异。CMP患者与心脏病专家接触的频率明显更高,接受超声心动图检查的频率也明显更高。在第一个随访观察年中,IG 的死亡率要高得多。有迹象表明,高血压患者的治疗质量有所提高。
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