Subjective fatigue in individuals with anxiety and mood disorders correlates with specific traits of obsessive-compulsive personality disorder

Neuroscience Applied Pub Date : 2024-01-01 Epub Date: 2024-02-15 DOI:10.1016/j.nsa.2024.104048
Agne Stanyte , Naomi A. Fineberg , Aurelija Podlipskyte , Julija Gecaite-Stonciene , Julius Burkauskas
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Abstract

Fatigue is a common debilitating symptom in individuals with anxiety and mood disorders, also known as common mental disorders (CMD). Aspects of fatigue are seen to be independently associated with the presence of obsessive-compulsive personality disorder (OCPD) in individuals with CMD. However, the relationship between different traits of OCPD and fatigue is still under-researched. Therefore, the aim of our study was to examine the associations between individual OCPD traits and fatigue in those with CMD. This cross-sectional study investigated 203 individuals (76.8% female, mean age 40.8 ± 11.8) attending a stress-related disorders day care unit. Participants were evaluated for OCPD traits by using the Compulsive Personality Assessment Scale and completed the Multidimensional Fatigue Inventory-20. Out of 203 participants, 42 (20.7%) fulfilled operational criteria for OCPD (73.8% female). Participants with OCPD had greater reduced motivation, mental and physical fatigue scores than those without OCPD (13.2 ± 3.6 vs. 14.5 ± 3.6, p = 0.035; 14.4 ± 4.3 vs. 16.1 ± 3.5, p = 0.023; 13.5 ± 4.3 vs. 15.0 ± 4.3, p = 0.049, respectively). In individuals with OCPD, higher levels of rigidity correlated with physical fatigue (ρ = 0.463, p = 0.002) and reduced activity (ρ = 0.363, p = 0.018), while preoccupation with details was associated with reduced motivation (ρ = 0.437, p = 0.004). In conclusion, in individuals with CMD and comorbid OCPD, several OCPD traits were significantly related to subjective measures of fatigue. As traits are considered stable features, there results suggest they might play a causative role in generating subjective fatigue in CMD.

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焦虑症和情绪障碍患者的主观疲劳感与强迫性人格障碍的特定特征有关
疲劳是焦虑症和情绪障碍(又称常见精神障碍(CMD))患者的常见衰弱症状。在患有常见精神障碍(CMD)的患者中,疲劳的某些方面被认为与强迫性人格障碍(OCPD)的存在独立相关。然而,关于强迫性人格障碍的不同特征与疲劳之间的关系的研究仍然不足。因此,我们的研究旨在探讨 CMD 患者的 OCPD 特征与疲劳之间的关系。这项横断面研究调查了 203 名在应激相关障碍日间护理中心就诊的患者(76.8% 为女性,平均年龄为 40.8 ± 11.8)。研究人员使用强迫性人格评估量表对参与者的 OCPD 特征进行了评估,并填写了多维疲劳量表-20。在 203 名参与者中,42 人(20.7%)符合 OCPD 的操作标准(73.8% 为女性)。与非 OCPD 患者相比,OCPD 患者的动机、精神和身体疲劳得分降低幅度更大(分别为 13.2 ± 3.6 vs. 14.5 ± 3.6,p = 0.035;14.4 ± 4.3 vs. 16.1 ± 3.5,p = 0.023;13.5 ± 4.3 vs. 15.0 ± 4.3,p = 0.049)。在 OCPD 患者中,较高程度的僵化与身体疲劳(ρ = 0.463,p = 0.002)和活动减少(ρ = 0.363,p = 0.018)相关,而对细节的专注与动机减少(ρ = 0.437,p = 0.004)相关。总之,在患有CMD和合并OCPD的个体中,几种OCPD特质与疲劳的主观测量结果有显著关系。由于这些特质被认为是稳定的特征,因此研究结果表明,它们可能在CMD主观疲劳的产生中起着诱因作用。
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