An in vitro comparison of calcium ions release and diffusion ability of calcium hydroxide-based intracanal medicament in combination with three different vehicles like propolis, chitosan, and propylene glycol

Pinku T. Thomas, J. Issac, P. Girija, Lekshmi S. Chandran, D. Arjun, A. Siddik
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Abstract

Calcium hydroxide, which is an intracanal medicament, is widely used in endodontics. Improvements can be made to its effectiveness, as calcium hydroxide is dependent on the vehicle. The study aims to compare and evaluate the release and diffusion ability of calcium hydroxide when mixed with – propolis, chitosan, and propylene glycol. For this study, 33 single-rooted extracted premolar teeth have been decoronated. After the working length and enlargement of the canals had been established, different preparations of calcium hydroxide with vehicles such as propolis, chitosan, and propylene glycol were loaded into the canals. Atomic absorption spectrophotometry was used to analyze the release of calcium ions in three groups, while a digital pH meter was used to determine an acid change. Atomic absorption spectrophotometry showed sustained releases of calcium ions and the digital pH meter showed increased diffusion capacity in the propylene glycol paste group in comparison to the other two groups. Propylene glycol vehicle made it easier to enter calcium hydroxide into the dentinal tubules.
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氢氧化钙类龋内药物与蜂胶、壳聚糖和丙二醇等三种不同载体的钙离子释放和扩散能力的体外比较
氢氧化钙是一种根管治疗药物,广泛用于牙髓治疗。由于氢氧化钙依赖于载体,因此可以改善其效果。 本研究旨在比较和评估氢氧化钙与蜂胶、壳聚糖和丙二醇混合后的释放和扩散能力。 在这项研究中,对 33 颗单根拔出的前臼齿进行了装饰。在确定了牙槽的工作长度和扩大程度后,将氢氧化钙的不同制剂与蜂胶、壳聚糖和丙二醇等载体一起装入牙槽。使用原子吸收分光光度法分析三组钙离子的释放情况,同时使用数字 pH 计测定酸性变化。 原子吸收分光光度法显示钙离子持续释放,数字 pH 计显示丙二醇糊剂组与其他两组相比扩散能力更强。 丙二醇载体使氢氧化钙更容易进入牙本质小管。
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