Enhanced dissolution rates of glibenclamide through solid dispersions on microcrystalline cellulose and mannitol, combined with phosphatidylcholine

IF 2.2 4区 医学 Q3 CHEMISTRY, MEDICINAL Drug Development and Industrial Pharmacy Pub Date : 2024-02-22 DOI:10.1080/03639045.2024.2321388
Wanlop Weecharangsan, Robert J. Lee
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Abstract

This study aimed to investigate the impact of physical solid dispersions of spray-dried glibenclamide (SG) on the surface of microcrystalline cellulose (MC) and mannitol (M) surfaces, as well as th...
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微晶纤维素和甘露醇与磷脂酰胆碱的固体分散体提高了格列本脲的溶解率
本研究旨在探讨喷雾干燥格列本脲(SG)物理固体分散体对微晶纤维素(MC)表面和甘露醇(M)表面的影响,以及格列本脲(SG)对微晶纤维素(MC)表面和甘露醇(M)表面的影响。
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来源期刊
CiteScore
6.80
自引率
0.00%
发文量
82
审稿时长
4.5 months
期刊介绍: The aim of Drug Development and Industrial Pharmacy is to publish novel, original, peer-reviewed research manuscripts within relevant topics and research methods related to pharmaceutical research and development, and industrial pharmacy. Research papers must be hypothesis driven and emphasize innovative breakthrough topics in pharmaceutics and drug delivery. The journal will also consider timely critical review papers.
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