Recent advances in discovery and biosynthesis of natural products from myxobacteria: an overview from 2017 to 2023

IF 10.2 1区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Natural Product Reports Pub Date : 2024-06-19 DOI:10.1039/d3np00062a
Chao-Yi Wang , Jia-Qi Hu , De-Gao Wang , Yue-Zhong Li , Changsheng Wu
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Abstract

Covering: 2017.01 to 2023.11

Natural products biosynthesized by myxobacteria are appealing due to their sophisticated chemical skeletons, remarkable biological activities, and intriguing biosynthetic enzymology. This review aims to systematically summarize the advances in the discovery methods, new structures, and bioactivities of myxobacterial NPs reported in the period of 2017–2023. In addition, the peculiar biosynthetic pathways of several structural families are also highlighted.

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从霉菌中发现和生物合成天然产物的最新进展:2017 年至 2023 年概览。
覆盖时间:2017.01 至 2023.11霉菌生物合成的天然产物因其复杂的化学骨架、显著的生物活性和引人入胜的生物合成酶学而极具吸引力。本综述旨在系统总结 2017-2023 年期间报道的粘菌 NPs 发现方法、新结构和生物活性方面的进展。此外,还重点介绍了几个结构家族的奇特生物合成途径。
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来源期刊
Natural Product Reports
Natural Product Reports 化学-生化与分子生物学
CiteScore
21.20
自引率
3.40%
发文量
127
审稿时长
1.7 months
期刊介绍: Natural Product Reports (NPR) serves as a pivotal critical review journal propelling advancements in all facets of natural products research, encompassing isolation, structural and stereochemical determination, biosynthesis, biological activity, and synthesis. With a broad scope, NPR extends its influence into the wider bioinorganic, bioorganic, and chemical biology communities. Covering areas such as enzymology, nucleic acids, genetics, chemical ecology, carbohydrates, primary and secondary metabolism, and analytical techniques, the journal provides insightful articles focusing on key developments shaping the field, rather than offering exhaustive overviews of all results. NPR encourages authors to infuse their perspectives on developments, trends, and future directions, fostering a dynamic exchange of ideas within the natural products research community.
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