The efficacy of antiaging cream with Oxalis dehradunensis R. ethanolic extract as skin aging care among woman agriculture workers.

IF 1.4 Q3 Pharmacology, Toxicology and Pharmaceutics Journal of Advanced Pharmaceutical Technology & Research Pub Date : 2024-01-01 Epub Date: 2024-01-15 DOI:10.4103/japtr.Japtr_388_23
Eka Lestari Mahyuni, Urip Harahap
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Abstract

Skin damage and aging are potential health problems for woman agriculture workers. This study aimed to test the efficacy of Oxalis dehradunensis ethanol extract formulated in antiaging cream preparations as an aging treatment in women agriculture workers. The method carried out was an experimental study on woman agriculture workers who were willing to volunteer. The experimental scenario conducted related to the physical quality of antiaging cream products and the efficacy of creams on the skin as an antiaging treatment. Physical quality parameters of antiaging cream include organoleptic assessment, cream emulsion, homogeneity, viscosity, pH, distribution, and skin irritation test to evaluate potential side effects. Skin aging efficacy assessments were conducted on 12 subjects divided into four formula concentration groups. The physical skin identification parameters measured are moisture, pore size, pigmentation or spots, and wrinkles using a skin analyzer. The results found that O. dehradunensis leaf extract formulated as an antiaging cream can neutralize free radicals and is an effective countermeasure against premature skin aging. There were significant differences in the skin characteristics of woman agriculture workers who participated as samples. The formula with 5% concentrate and 7% extract of O. dehradunensis has provided a reaction and is more effective in continuous treatment. It provides skin moisture changes of more than 300%, disguises pore size and good pigmentation, and reduces wrinkles of farmers who are constantly exposed to chemicals and free radicals in their agricultural activities. The leaf extracts antiaging cream showed more significant changes in moisture and skin pigmentation. It was concluded that the use of O. dehradunensis leaf extract as the core ingredient of antiaging cream can be an innovation that is beneficial to the health of the farming community, especially among women agriculture workers.

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用 Oxalis dehradunensis R.乙醇提取物制成的抗衰老霜对农业女工皮肤老化护理的功效。
皮肤损伤和衰老是农业女工潜在的健康问题。本研究旨在测试将 Oxalis dehradunensis 乙醇提取物配制成抗衰老霜制剂作为农业女工衰老治疗剂的功效。研究方法是对自愿参加的农业女工进行实验研究。实验情景涉及抗衰老面霜产品的物理质量和面霜作为抗衰老治疗对皮肤的功效。抗衰老面霜的物理质量参数包括感官评估、面霜乳液、均匀度、粘度、pH 值、分布和皮肤刺激测试,以评估潜在的副作用。对 12 名受试者进行了皮肤老化功效评估,分为四个配方浓度组。使用皮肤分析仪测量的皮肤物理识别参数包括水分、毛孔大小、色素沉着或斑点以及皱纹。结果发现,O. dehradunensis 叶提取物配制成的抗衰老霜可以中和自由基,是防止皮肤过早衰老的有效对策。作为样本的农业女工的皮肤特征存在明显差异。含有 5%浓缩物和 7%O.dehradunensis提取物的配方产生了反应,在持续治疗中更为有效。它能使皮肤水分变化超过 300%,掩盖毛孔粗大和良好的色素沉着,并减少在农业活动中经常接触化学品和自由基的农民的皱纹。叶提取物抗衰老霜在水分和皮肤色素沉着方面的变化更为显著。研究得出结论,使用 O. dehradunensis 叶提取物作为抗衰老霜的核心成分是一种创新,有益于农民群体的健康,尤其是女性农业工人的健康。
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来源期刊
CiteScore
2.00
自引率
7.10%
发文量
44
审稿时长
20 weeks
期刊介绍: Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is an Official Publication of Society of Pharmaceutical Education & Research™. It is an international journal published Quarterly. Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is available in online and print version. It is a peer reviewed journal aiming to communicate high quality original research work, reviews, short communications, case report, Ethics Forum, Education Forum and Letter to editor that contribute significantly to further the scientific knowledge related to the field of Pharmacy i.e. Pharmaceutics, Pharmacology, Pharmacognosy, Pharmaceutical Chemistry. Articles with timely interest and newer research concepts will be given more preference.
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