The Future of Food Allergy Management: Advancements in Therapies.

IF 5.4 2区 医学 Q1 ALLERGY Current Allergy and Asthma Reports Pub Date : 2024-04-01 Epub Date: 2024-02-23 DOI:10.1007/s11882-024-01133-1
Idil D Ezhuthachan, Michele Beaudoin, Anna Nowak-Wegrzyn, Brian P Vickery
{"title":"The Future of Food Allergy Management: Advancements in Therapies.","authors":"Idil D Ezhuthachan, Michele Beaudoin, Anna Nowak-Wegrzyn, Brian P Vickery","doi":"10.1007/s11882-024-01133-1","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>To review current and future treatment options for IgE-mediated food allergy.</p><p><strong>Recent findings: </strong>Recent years have seen major developments in both allergen-specific and allergen-non-specific treatment options, with the first FDA-approved peanut oral immunotherapy (OIT) product becoming available in 2020. In addition to OIT, other immunotherapy modalities, biologics, adjunct therapies, and novel therapeutics are under investigation. Food allergy is a potentially life-threatening condition associated with a significant psychosocial impact. Numerous products and protocols are under investigation, with most studies focusing on OIT. A high rate of adverse events, need for frequent office visits, and cost remain challenges with OIT. Further work is needed to unify outcome measures, develop treatment protocols that minimize adverse events, establish demographic and clinical factors that influence candidate selection, and identify patient priorities.</p>","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":" ","pages":"161-171"},"PeriodicalIF":5.4000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Allergy and Asthma Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11882-024-01133-1","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/23 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"ALLERGY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose of review: To review current and future treatment options for IgE-mediated food allergy.

Recent findings: Recent years have seen major developments in both allergen-specific and allergen-non-specific treatment options, with the first FDA-approved peanut oral immunotherapy (OIT) product becoming available in 2020. In addition to OIT, other immunotherapy modalities, biologics, adjunct therapies, and novel therapeutics are under investigation. Food allergy is a potentially life-threatening condition associated with a significant psychosocial impact. Numerous products and protocols are under investigation, with most studies focusing on OIT. A high rate of adverse events, need for frequent office visits, and cost remain challenges with OIT. Further work is needed to unify outcome measures, develop treatment protocols that minimize adverse events, establish demographic and clinical factors that influence candidate selection, and identify patient priorities.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
食物过敏管理的未来:疗法的进步。
综述目的回顾 IgE 介导的食物过敏目前和未来的治疗方案:近年来,过敏原特异性治疗方案和过敏原非特异性治疗方案都取得了重大进展,美国食品及药物管理局批准的首个花生口服免疫疗法(OIT)产品将于 2020 年上市。除口服免疫疗法外,其他免疫疗法方式、生物制剂、辅助疗法和新型疗法也在研究之中。食物过敏是一种可能危及生命的疾病,会对社会心理产生重大影响。目前正在对许多产品和方案进行研究,其中大多数研究侧重于 OIT。不良反应发生率高、需要频繁就诊以及成本问题仍然是 OIT 面临的挑战。我们需要进一步开展工作,以统一结果衡量标准,制定可最大限度减少不良反应的治疗方案,确定影响候选者选择的人口和临床因素,并确定患者的优先权。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
11.20
自引率
1.80%
发文量
21
审稿时长
6-12 weeks
期刊介绍: The aim of Current Allergy and Asthma Reports is to systematically provide the views of highly selected experts on current advances in the fields of allergy and asthma and highlight the most important papers recently published. All reviews are intended to facilitate the understanding of new advances in science for better diagnosis, treatment, and prevention of allergy and asthma. We accomplish this aim by appointing international experts in major subject areas across the discipline to review select topics emphasizing recent developments and highlighting important new papers and emerging concepts. We also provide commentaries from well-known figures in the field, and an Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. Over a one- to two-year period, readers are updated on all the major advances in allergy and asthma.
期刊最新文献
Effect of Dupilumab in CRSwNP Sinonasal Outcomes from Real Life Studies: A Systematic Review with Meta-analysis. Hypersensitivity Reactions to Anticonvulsants. The Impact of the Indoor Environment on Childhood Asthma. Parosmia: Pathophysiology and Management. Effects of Food Processing on Allergenicity.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1