Revolutionizing and identifying novel drug targets in Citrobacter koseri via subtractive proteomics and development of a multi-epitope vaccine using reverse vaccinology and immuno-informatics

Israr Fatima, Fahad M. Alshabrmi, Tariq Aziz, Abdulhakeem S. Alamri, Majid Alhomrani, Saad Alghamdi, Reem Ahmad Alghuraybi, Ahmad O. Babalghith, Ghazi A. Bamagous, Zain Alhindi, Anas S. Dablool, Areej A. Alhhazmi, Mashael W. Alruways
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Abstract

Citrobacter koseri is a gram-negative rod that has been linked to infections in people with significant comorbidities and immunocompromised immune systems. It is most commonly known to cause urinar...
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通过减法蛋白质组学彻底改变和确定柯氏柠檬酸杆菌中的新型药物靶点,并利用反向疫苗学和免疫信息学开发多表位疫苗
柯氏柠檬酸杆菌是一种革兰氏阴性杆菌,与患有严重合并症和免疫系统低下的人的感染有关。它最常见的致病菌是尿路感染。
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