Mental health, coping, and protective factors in mothers of children with 22q11.2 deletion syndrome

IF 1.6 3区 医学 Q3 GENETICS & HEREDITY American Journal of Medical Genetics Part B: Neuropsychiatric Genetics Pub Date : 2024-02-26 DOI:10.1002/ajmg.b.32973
Haley McBride, Nandini Jhawar, Laurie Boucicaut, Carrie E. Bearden, Wendy R. Kates, Sarah E. Woolf-King, Kevin M. Antshel
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Abstract

Compared to the large body of maternal mental health research for other pediatric disorders, we know far less about the experience of mothers of children with 22q11DS. This study investigates the coping methods, protective factors, and mental health of this population. These findings might lead to better support for 22q11DS maternal mental health. An international sample of 71 mothers (M = 40.5 years) of children with 22q11DS (M = 9.2 years) was recruited and completed an online survey assessing maternal mental health (symptoms of depression, anxiety, traumatic stress, general stress, and alcohol consumption), coping methods, and mental health protective factors (social support, dyadic adjustment, parenting competence). Maternal ratings of child mental health symptoms were also obtained. Mothers' self-report revealed a high percentage who screened positive for elevated levels of general stress (69%), hazardous alcohol consumption (30.9%), traumatic stress (33.8%), anxiety (26.8%), and depression (26.8%). After controlling for demographic variables and child mental health symptoms, maternal self-reported maladaptive coping methods were positively associated with maternal symptoms of depression, anxiety, stress, and traumatic stress. Reducing maladaptive coping methods may be a promising intervention for improving mental health in mothers of children with 22q11DS.

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22q11.2 缺失综合征患儿母亲的心理健康、应对能力和保护因素。
与针对其他儿科疾病的大量孕产妇心理健康研究相比,我们对 22q11DS 患儿母亲的经历知之甚少。本研究调查了这一人群的应对方法、保护因素和心理健康。这些发现可能会为 22q11DS 母亲的心理健康提供更好的支持。本研究招募了 71 位 22q11DS 患儿(男 = 9.2 岁)的母亲(男 = 40.5 岁)作为国际样本,并完成了一项在线调查,评估了母亲的心理健康(抑郁症状、焦虑、创伤性压力、一般压力和饮酒)、应对方法和心理健康保护因素(社会支持、二元适应、养育能力)。此外,还获得了母亲对儿童心理健康症状的评分。从母亲的自我报告中可以看出,有很高比例的母亲在一般压力(69%)、危险饮酒(30.9%)、创伤性压力(33.8%)、焦虑(26.8%)和抑郁(26.8%)方面表现出阳性。在控制了人口统计学变量和儿童心理健康症状后,母亲自我报告的不良应对方法与母亲的抑郁、焦虑、压力和创伤性压力症状呈正相关。减少适应不良的应对方法可能是改善 22q11DS 患儿母亲心理健康的一种有效干预措施。
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来源期刊
CiteScore
5.90
自引率
7.10%
发文量
40
审稿时长
4-8 weeks
期刊介绍: Neuropsychiatric Genetics, Part B of the American Journal of Medical Genetics (AJMG) , provides a forum for experimental and clinical investigations of the genetic mechanisms underlying neurologic and psychiatric disorders. It is a resource for novel genetics studies of the heritable nature of psychiatric and other nervous system disorders, characterized at the molecular, cellular or behavior levels. Neuropsychiatric Genetics publishes eight times per year.
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