Completion of multidose vaccine series in early childhood: current challenges and opportunities.

IF 3.6 3区 医学 Q2 INFECTIOUS DISEASES Current Opinion in Infectious Diseases Pub Date : 2024-06-01 Epub Date: 2024-03-01 DOI:10.1097/QCO.0000000000001007
Sarah Y Michels, Matthew F Daley, Sophia R Newcomer
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Abstract

Purpose of review: Completion of all doses in multidose vaccine series provides optimal protection against preventable infectious diseases. In this review, we describe clinical and public health implications of multidose vaccine series noncompletion, including current challenges to ensuring children receive all recommended vaccinations. We then highlight actionable steps toward achieving early childhood immunization goals.

Recent findings: Although coverage levels are high for most early childhood vaccinations, rates of completion are lower for vaccinations that require multiple doses. Recent research has shown that lower family socioeconomic status, a lack of health insurance coverage, having multiple children in the household, and moving across state lines are associated with children failing to complete multidose vaccine series. These findings provide contextual evidence to support that practical challenges to accessing immunization services are impediments to completion of multidose series. Strategies, including reminder/recall, use of centralized immunization information systems, and clinician prompts, have been shown to increase immunization rates. Re-investing in these effective interventions and modernizing the public health infrastructure can facilitate multidose vaccine series completion.

Summary: Completion of multidose vaccine series is a challenge for immunization service delivery. Increased efforts are needed to address remaining barriers and improve vaccination coverage in the United States.

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完成幼儿多剂量疫苗系列接种:当前的挑战与机遇。
审查目的:完成多剂量疫苗系列的所有剂量接种可为预防可预防的传染病提供最佳保护。在这篇综述中,我们阐述了未完成多剂量疫苗接种对临床和公共卫生的影响,包括当前确保儿童接种所有推荐疫苗所面临的挑战。然后,我们强调了实现儿童早期免疫接种目标的可行步骤:尽管大多数儿童早期疫苗接种的覆盖率较高,但需要接种多剂疫苗的儿童完成接种的比例较低。最近的研究表明,较低的家庭社会经济地位、缺乏医疗保险、家中有多个孩子以及跨州迁移与儿童未能完成多剂量疫苗接种系列有关。这些研究结果提供了背景证据,证明获得免疫接种服务的实际困难是完成多剂量系列疫苗接种的障碍。事实证明,包括提醒/召回、使用集中免疫信息系统和临床医生提示在内的策略可提高免疫接种率。对这些有效干预措施的再投资以及公共卫生基础设施的现代化可促进多剂量疫苗接种的完成。美国需要加大力度解决剩余障碍,提高疫苗接种覆盖率。
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来源期刊
CiteScore
6.70
自引率
2.60%
发文量
121
审稿时长
6-12 weeks
期刊介绍: This reader-friendly, bimonthly resource provides a powerful, broad-based perspective on the most important advances from throughout the world literature. Featuring renowned guest editors and focusing exclusively on two topics, every issue of Current Opinion in Infectious Disease delivers unvarnished, expert assessments of developments from the previous year. Insightful editorials and on-the-mark invited reviews cover key subjects such as HIV infection and AIDS; skin and soft tissue infections; respiratory infections; paediatric and neonatal infections; gastrointestinal infections; tropical and travel-associated diseases; and antimicrobial agents.
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