Synthesis of Deuterated Compounds by Flow Chemistry

IF 3 4区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY ChemPlusChem Pub Date : 2024-03-07 DOI:10.1002/cplu.202300744
Dr. Shintaro Kamio, Prof. Dr. Kazuhiro Okamoto, Prof. Dr. Takehiro Yamagishi, Prof. Dr. Aiichiro Nagaki
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Abstract

Development of the efficient and practical method for the synthesis of deuterated compounds which occupies the broadest area among stable isotopes is one of the most essential issues toward the industrial advance and building a sustainable society. This review describes recent advances in deuteration reactions, where the continuous flow chemistry plays pivotal roles for the successful installation of deuterium atom into diverse organic frameworks, opening new fields of isotope-based synthetic chemistry.

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通过流动化学合成氘代化合物。
氘代化合物在稳定同位素中占有最广泛的领域,开发高效实用的氘代化合物合成方法是实现工业进步和建设可持续社会的最基本问题之一。本综述介绍了氘化反应的最新进展,其中连续流化学在将氘原子成功装入各种有机框架中发挥了关键作用,为基于同位素的合成化学开辟了新的领域。
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来源期刊
ChemPlusChem
ChemPlusChem CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
5.90
自引率
0.00%
发文量
200
审稿时长
1 months
期刊介绍: ChemPlusChem is a peer-reviewed, general chemistry journal that brings readers the very best in multidisciplinary research centering on chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. Fully comprehensive in its scope, ChemPlusChem publishes articles covering new results from at least two different aspects (subfields) of chemistry or one of chemistry and one of another scientific discipline (one chemistry topic plus another one, hence the title ChemPlusChem). All suitable submissions undergo balanced peer review by experts in the field to ensure the highest quality, originality, relevance, significance, and validity.
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