Higher dietary protein/energy ratio is associated with a lower risk for obesity in older women with type 2 diabetes: Cross-sectional analysis of Japanese patients with type 2 diabetes mellitus (JDDM75)

IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Human Nutrition and Metabolism Pub Date : 2024-03-02 DOI:10.1016/j.hnm.2024.200257
Efrem d'Ávila Ferreira , Mariko Hatta , Khin Laymon , Izumi Ikeda , Mizuki Takeuchi , Yasunaga Takeda , Sakiko Yoshizawa Morikawa , Chika Horikawa , Noriko Kato , Hiroshi Maegawa , Kazuya Fujihara , Hirohito Sone
{"title":"Higher dietary protein/energy ratio is associated with a lower risk for obesity in older women with type 2 diabetes: Cross-sectional analysis of Japanese patients with type 2 diabetes mellitus (JDDM75)","authors":"Efrem d'Ávila Ferreira ,&nbsp;Mariko Hatta ,&nbsp;Khin Laymon ,&nbsp;Izumi Ikeda ,&nbsp;Mizuki Takeuchi ,&nbsp;Yasunaga Takeda ,&nbsp;Sakiko Yoshizawa Morikawa ,&nbsp;Chika Horikawa ,&nbsp;Noriko Kato ,&nbsp;Hiroshi Maegawa ,&nbsp;Kazuya Fujihara ,&nbsp;Hirohito Sone","doi":"10.1016/j.hnm.2024.200257","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>To analyze the association between the dietary protein/energy ratio and percentages of dietary animal and plant protein and obesity in Japanese patients with type 2 diabetes.</p></div><div><h3>Design</h3><p>This was a cross-sectional study. Obesity was defined as BMI ≥25 kg/m<sup>2</sup>. Data were collected for all study participants and stratified according to age and sex. Diet was assessed via a food frequency questionnaire.</p></div><div><h3>Setting</h3><p>26 clinics participating in the Japan Diabetes Clinical Data Management Study Group (JDDM) from December 2014 to December 2019.</p></div><div><h3>Participants</h3><p>1567 Japanese out patients with type 2 diabetes (63.1% men; mean age 62.3 ± 11.6 years).</p></div><div><h3>Results</h3><p>In all participants, multivariate analysis with adjustment by major confounders showed a significant inverse association in those in the highest quartile of the protein/energy ratio (mean 17.7%) with obesity (OR = 0.588, 95% CI = 0.435-0.794; p trend = 00.007), but after the addition of vegetable intake it became non-significant. In the age- and sex-stratified analysis, a high protein/energy ratio (mean 15.6%) was inversely associated with obesity in older women only (OR = 0.280, 95% CI = 0.123-0.638), which remained significant after adjustment of individual food groups correlated with protein. No association between percentages of dietary animal or plant protein and obesity was found.</p></div><div><h3>Conclusions</h3><p>In older women only, a higher dietary protein/energy ratio was associated with lower obesity after adjustment by confounders and individual food groups correlated with protein intake. Future longitudinal research that includes data on food groups as well as age- and sex-stratification of participants is recommended to further clarify this relationship.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149724000197/pdfft?md5=eea219bb23834311730143e53ce7123d&pid=1-s2.0-S2666149724000197-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Nutrition and Metabolism","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666149724000197","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0

Abstract

Objective

To analyze the association between the dietary protein/energy ratio and percentages of dietary animal and plant protein and obesity in Japanese patients with type 2 diabetes.

Design

This was a cross-sectional study. Obesity was defined as BMI ≥25 kg/m2. Data were collected for all study participants and stratified according to age and sex. Diet was assessed via a food frequency questionnaire.

Setting

26 clinics participating in the Japan Diabetes Clinical Data Management Study Group (JDDM) from December 2014 to December 2019.

Participants

1567 Japanese out patients with type 2 diabetes (63.1% men; mean age 62.3 ± 11.6 years).

Results

In all participants, multivariate analysis with adjustment by major confounders showed a significant inverse association in those in the highest quartile of the protein/energy ratio (mean 17.7%) with obesity (OR = 0.588, 95% CI = 0.435-0.794; p trend = 00.007), but after the addition of vegetable intake it became non-significant. In the age- and sex-stratified analysis, a high protein/energy ratio (mean 15.6%) was inversely associated with obesity in older women only (OR = 0.280, 95% CI = 0.123-0.638), which remained significant after adjustment of individual food groups correlated with protein. No association between percentages of dietary animal or plant protein and obesity was found.

Conclusions

In older women only, a higher dietary protein/energy ratio was associated with lower obesity after adjustment by confounders and individual food groups correlated with protein intake. Future longitudinal research that includes data on food groups as well as age- and sex-stratification of participants is recommended to further clarify this relationship.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
膳食蛋白质/能量比率越高,2 型糖尿病老年妇女肥胖的风险越低:日本 2 型糖尿病患者的横断面分析(JDDM75)
目的 分析日本 2 型糖尿病患者的膳食蛋白质/能量比、膳食动物蛋白和植物蛋白百分比与肥胖之间的关系。肥胖定义为体重指数≥25 kg/m2。研究收集了所有参与者的数据,并根据年龄和性别进行了分层。研究地点2014年12月至2019年12月期间参与日本糖尿病临床数据管理研究小组(JDDM)的26家诊所。参与者1567名日本2型糖尿病患者(63.1%为男性;平均年龄62.3 ± 11.6岁)。结果 在所有参与者中,根据主要混杂因素进行调整的多变量分析表明,蛋白质/能量比最高四分位数(平均 17.7%)的人与肥胖有显著的反向关系(OR = 0.588,95% CI = 0.435-0.794;P 趋势 = 00.007),但在增加蔬菜摄入量后,这种关系变得不显著。在按年龄和性别进行的分层分析中,蛋白质/能量比率高(平均为 15.6%)与肥胖成反比(OR = 0.280,95% CI = 0.123-0.638),仅在老年妇女中存在,在调整了与蛋白质相关的个别食物组别后,该比率仍然显著。结论 仅在老年妇女中,在对混杂因素和与蛋白质摄入相关的个别食物组进行调整后,较高的膳食蛋白质/能量比与较低的肥胖率相关。建议今后开展纵向研究,包括食物组数据以及参与者的年龄和性别分层,以进一步阐明这种关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Human Nutrition and Metabolism
Human Nutrition and Metabolism Agricultural and Biological Sciences-Food Science
CiteScore
1.50
自引率
0.00%
发文量
30
审稿时长
188 days
期刊最新文献
Contribution of body adiposity index and conicity index in prediction of metabolic syndrome risk and components Effectiveness of nutritional supplements (vitamins, minerals, omega-3, and probiotics) in preventing and treating COVID-19 and viral respiratory infections Prevalence of hypertension and its associated risk factors during COVID-19 pandemic in the capital of Bangladesh Diet and gut microbiome: Impact of each factor and mutual interactions on prevention and treatment of type 1, type 2, and gestational diabetes mellitus Dietary practices of type 2 diabetes mellitus patients concerning Pender's health Promotion Model in Lalitpur district, Nepal
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1