Outcomes of conservative management in patients with nutcracker syndrome.

IF 1.5 Phlebology Pub Date : 2024-07-01 Epub Date: 2024-03-07 DOI:10.1177/02683555241238772
Sabit Sarikaya, Ozge Altas, Mustafa Mert Ozgur, Hakan Hancer, Betul Ayca Ozdere, Tanil Ozer, Mehmet Aksut, Murat Bulent Rabus, Kamile Ozeren Topcu, Tolga Bas, Kaan Kirali
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Abstract

Objective: This study aims to evaluate outcomes in nutcracker syndrome patients with tolerable symptoms and treated conservatively without invasive interventions.

Methods: This prospective study included patients treated conservatively. Promoting weight gain, the endpoint of the study was spontaneous resolution of symptoms.

Results: Sixteen patients (75% female and mean age 24.4 ± 3.5 years) underwent conservative management. Over a mean follow-up of 27.3 months [13-42, interquartile range (IQR)], the diameter ratio (5.5 [5-6.5, IQR] vs 4.3 [4.1-6], p = NS), the peak velocity ratio (6 [5-7, IQR] vs 4.8 [4.8-5.8], p = NS), beak angle (27° [24-30, IQR] vs 29° [24-32]; p = NS), and aortomesenteric angle (26° [23-29, IQR] vs 28° [24-30]; p = NS) exhibited no statistically significant changes. Complete resolution and improvement of symptoms were 28.5% and 31.4%, respectively, while 68.5% remained unchanged.

Conclusions: This study shows that a conservative approach contributes to the spontaneous improvement or complete resolution in young adult patients with mild symptoms.

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胡桃钳综合征患者的保守治疗效果。
研究目的本研究旨在评估胡桃夹综合征患者的治疗效果,这些患者的症状可以忍受,并且接受了保守治疗,没有进行侵入性干预:这项前瞻性研究包括接受保守治疗的患者。方法:这项前瞻性研究包括接受保守治疗的患者,促进体重增加,研究终点为症状的自发缓解:16名患者(75%为女性,平均年龄(24.4 ± 3.5)岁)接受了保守治疗。在平均 27.3 个月[13-42 个月,四分位数间距 (IQR)]的随访中,直径比(5.5 [5-6.5, IQR] vs 4.3 [4.1-6], p = NS)、峰值速度比(6 [5-7, IQR] vs 4.8 [4.8-5.8],p = NS)、喙角(27° [24-30, IQR] vs 29° [24-32];p = NS)和主动脉与肠道夹角(26° [23-29, IQR] vs 28° [24-30];p = NS)均无统计学意义上的显著变化。症状完全缓解和改善的比例分别为 28.5% 和 31.4%,68.5% 的患者症状保持不变:本研究表明,保守疗法有助于症状轻微的年轻成人患者自发改善或完全缓解症状。
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