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The impact of stent protrusion into the inferior vena cava or jailing of the contralateral iliac vein on the incidence of contralateral deep vein thrombosis following venous stenting. 支架突入下腔静脉或对侧髂静脉狭窄对静脉支架术后对侧深静脉血栓形成发生率的影响。
Pub Date : 2025-03-01 Epub Date: 2024-08-13 DOI: 10.1177/02683555241273752
Duy Nguyen, Karl Pappas, Shreya Mahadevan, Levan Sulakvelidze, Richard Kennedy, Gaurav Lakhanpal, Sanjiv Lakhanpal, Peter J Pappas

Objective: Iliac vein stenting is the standard of care for patients with pelvic venous disorders secondary to symptomatic iliac vein outflow obstruction. Venous stents are often extended proximally into the inferior vena cava (IVC) which may result in partial or complete coverage of the contralateral iliac vein. The purpose of this investigation is to determine if extension of iliac vein stents into the IVC results in increased risk of contralateral deep venous thrombosis (DVT).

Methods: We retrospectively reviewed prospectively collected data from 409 patients who underwent iliac vein stenting at the Center for Vascular Medicine (CVM) from 2019 to 2020. Stent type, covered territories, initial and follow-up consults, ultrasound and operative reports were reviewed to assess for incidence of post-implantation DVT. Patients were stratified into three groups: Iliac vein stents which protruded into the IVC, stents that completely covered the orifice of the contralateral iliac vein and those with no stent protrusion into the IVC.

Results: Out of 409 patients, the average age was 53.96 ± 13.40 years with 94 males and 315 females. All stents placed were Venovo stents and all iliac vein lesions were non-thrombotic stenoses. The average follow-up period was 14.35 ± 10.09 months. The most common territories stented were the IVC-LCIV-LEIV (n = , 74%) and the IVC-RCIV-REIV (n = , 26%). Stent protrusion and distance into the IVC in millimeters (mm) was the following: Partial protrusion (n = 314, 77%, 27.6 ± 19.1), jailing of the contralateral iliac vein (n = 78, 19%, 45.9 ± 18.6), no protrusion (n = 16, 4%). The overall DVT rate post-implantation was 0.49% (n = 2). No DVTs ipsilateral to the index stent were identified and both DVTs were contralateral DVTs. A hypercoaguable disorder was reported in 6 patients (1.5%). There were no significant differences in prevalence of contralateral DVT between the three groups. (p = .35).

Conclusion: The rate of contralateral DVTs post iliac vein stenting with Nitonol based stents is extremely low. Partial or complete coverage of the contralateral iliac vein via stenting does not result in an increased incidence of contralateral DVT in the short-term. Longer follow up is needed to determine if contralateral DVTs occur after long-term implantation.

目的:髂静脉支架植入术是治疗继发于症状性髂静脉流出道阻塞的盆腔静脉疾病患者的标准疗法。静脉支架通常会向近端延伸至下腔静脉(IVC),这可能会导致部分或完全覆盖对侧髂静脉。本研究旨在确定髂静脉支架延伸至 IVC 是否会增加对侧深静脉血栓形成(DVT)的风险:我们回顾性审查了2019年至2020年期间在血管医学中心(CVM)接受髂静脉支架植入术的409名患者的前瞻性数据。回顾了支架类型、覆盖区域、初次和随访咨询、超声和手术报告,以评估植入后深静脉血栓的发生率。患者被分为三组:髂静脉支架突入内静脉、支架完全覆盖对侧髂静脉口以及支架未突入内静脉:在 409 名患者中,平均年龄为 53.96±13.40 岁,其中男性 94 人,女性 315 人。所有植入的支架均为 Venovo 支架,所有髂静脉病变均为非血栓性狭窄。平均随访时间为(14.35 ± 10.09)个月。最常见的支架区域是IVC-LCIV-LEIV(n = ,74%)和IVC-RCIV-REIV(n = ,26%)。支架突出和进入 IVC 的距离(毫米)如下:部分突出(n = 314,77%,27.6 ± 19.1),对侧髂静脉阻塞(n = 78,19%,45.9 ± 18.6),无突出(n = 16,4%)。植入后深静脉血栓的总发生率为 0.49%(n = 2)。没有发现同侧的深静脉血栓,两个深静脉血栓都是对侧深静脉血栓。有 6 名患者(1.5%)报告出现高凝状态。三组患者的对侧深静脉血栓发生率无明显差异。(P=0.35):结论:使用 Nitonol 支架进行髂静脉支架置入术后,对侧深静脉血栓的发生率极低。通过支架部分或完全覆盖对侧髂静脉在短期内不会导致对侧深静脉血栓发生率增加。要确定长期植入后是否会发生对侧深静脉血栓,还需要更长时间的随访。
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引用次数: 0
Selected phlebological abstracts.
Pub Date : 2025-03-01 Epub Date: 2025-01-30 DOI: 10.1177/02683555251317274
Lowell S Kabnick, Kathleen Ozsvath, Jorge H Ulloa
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引用次数: 0
Analysis of the efficacy of angiojet percutaneous mechanical thrombectomy combined with catheter-directed thrombolysis versus catheter-directed thrombolysis alone in the treatment of subacute iliofemoral deep venous thrombosis in elderly patients. 在治疗老年患者亚急性髂股深静脉血栓时,分析血管喷射经皮机械血栓切除术联合导管引导溶栓与单纯导管引导溶栓的疗效。
Pub Date : 2025-03-01 Epub Date: 2024-08-14 DOI: 10.1177/02683555241273064
Luyi Cong, Lihua Huang, Benfang Fan, Xin Hong, Lingyu Ma, Tianan Huang

Purpose: To analysis the clinical efficacy of Angiojet percutaneous mechanical thrombectomy (PMT) combined with Catheter-Directed Thrombolysis (CDT) compared to CDT in treatment of subacute iliofemoral deep venous thrombosis (IFDVT) in elderly patients.

Methods: A retrospective analysis of the clinical data of 117 elderly patients hospitalized for subacute IFDVT was conducted. The patients'basic perioperative data and 2-years follow-up data were compared.

Results: Group A (PMT + CDT) had a more patients reaching Grade III thrombus clearance, and a lower thrombolysis time, dosage of thrombolytic drugs, hospital stay, and bleeding incidence compared to Group B (CDT). There was a statistically significant difference in the occurrence rate of severe PTS within 2 years (p < 0.05).

Conclusion: In treating elderly patients with subacute IFDVT, PMT + CDT effectively reduces the thrombus burden and the dosage of thrombolytic drugs, shortens the hospital stay, and importantly, reduces the occurrence rate of severe PTS within 2 years.

目的:分析Angiojet经皮机械取栓术(PMT)联合导管引导溶栓术(CDT)治疗老年患者亚急性髂股深静脉血栓(IFDVT)的临床疗效:对117名因亚急性髂股深静脉血栓形成住院的老年患者的临床数据进行了回顾性分析。结果:A 组(PMT + CDT)和 B 组(PMT + CDT)的患者在术后 2 年的随访中均获得了良好的治疗效果:结果:与 B 组(CDT)相比,A 组(PMT + CDT)达到 III 级血栓清除率的患者更多,溶栓时间、溶栓药物用量、住院时间和出血发生率更低。2年内严重PTS的发生率差异有统计学意义(P<0.05):结论:在治疗亚急性 IFDVT 老年患者时,PMT + CDT 可有效减少血栓负荷和溶栓药物用量,缩短住院时间,更重要的是,可降低 2 年内严重 PTS 的发生率。
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引用次数: 0
A randomized controlled study to evaluate the safety and feasibility of concomitant transluminal injection of foam sclerosant combined with endovenous laser ablation in patients with incompetent small saphenous veins. 一项随机对照研究,旨在评估小隐静脉闭塞患者同时进行腔内注射泡沫硬化剂和静脉腔内激光消融术的安全性和可行性。
Pub Date : 2025-03-01 Epub Date: 2024-08-29 DOI: 10.1177/02683555241276709
Satoshi Watanabe, Atsunori Okamura, Mutsumi Iwamoto, Akinori Sumiyoshi, Kota Tanaka, Heitaro Watanabe, Yoshitaka Iwanaga, Katsuomi Iwakura

Objectives: To compare foam sclerotherapy through the access sheath (transluminal foam sclerotherapy [TLFS]) combined with endovenous laser ablation (EVLA) with EVLA alone in terms of safety and one-year venous clinical severity score (VCSS) changes in patients with small saphenous vein incompetence.

Methods: During EVLA, the sheath tip was placed around the targeted tributary vein, and the sclerosant was injected via the side port. Outcomes assessed at 1 day, 1 week, 1 month, and 1 year included VCSS changes, residual or recurrent reflux, the need for secondary interventions, and other related complications.

Results: The change in VCSS did not reach the minimum clinically important difference. Otherwise, TLFS reduced residual or recurrent reflux of the tributary using the TLFS (3/74 legs) compared with the EVLA alone (12/77 legs) (p = .027).

Conclusions: TLFS is a safe and feasible procedure that reduces residual or recurrent reflux of the tributary vein compared with truncal EVLA alone.

目的比较通过入路鞘进行泡沫硬化剂治疗(腔内泡沫硬化剂治疗[TLFS])联合静脉腔内激光消融术(EVLA)与单独使用EVLA在安全性和一年静脉临床严重程度评分(VCSS)变化方面的效果:EVLA过程中,将鞘尖置于目标支静脉周围,通过侧孔注入硬化剂。1天、1周、1个月和1年后的评估结果包括VCSS变化、残留或复发反流、二次干预的需要以及其他相关并发症:结果:VCSS 的变化未达到最小临床重要差异。此外,与单独使用 EVLA(12/77 条腿)相比,使用 TLFS 减少了支流残留或复发性反流(3/74 条腿)(p = .027):结论:TLFS是一种安全可行的手术,与单纯截肢EVLA相比,TLFS可减少支静脉的残留或复发性反流。
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引用次数: 0
The open vein hypothesis - is it the whole story? 开放静脉假说--它是故事的全部吗?
Pub Date : 2025-03-01 Epub Date: 2024-08-18 DOI: 10.1177/02683555241271914
Benedict Rh Turner, Marwah Salih, Jessica Shea, Adam M Gwozdz, Alun H Davies
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引用次数: 0
Efficacy of ultrasound in the evaluation of iliac vein stenting. 超声波在评估髂静脉支架植入术中的功效。
Pub Date : 2025-03-01 Epub Date: 2024-08-26 DOI: 10.1177/02683555241276565
Hannah Clode, Elizabeth Brooke Spencer, Jacqueline Nelson, Elisabeth S Horne

Objectives: The current study evaluated the efficacy of iliac and IVC ultrasound alone for follow-up evaluation of iliac vein stents in patients with pelvic venous disorders or iliac occlusion from chronic deep vein thrombosis. Methods: A retrospective single site cohort study was conducted by evaluating the most recent 100 iliac vein and inferior vena cava ultrasounds in patients who had undergone iliac vein stenting. Inclusion criteria included a history of iliac vein stent placement. Exclusion criteria included patients under 18-years-old, duplicates of the same patient, and pregnancy at the time of ultrasound. The degree of visualization for color flow, gray scale, and phasicity were determined and classified into the following categories: complete, partial, or none. In addition, each chart was assessed for external compression, in-stent narrowing, and requirements for further imaging. Results: Of the 100 iliac vein and IVC ultrasounds assessed in this review, 99 of the ultrasounds were sufficient for evaluation during follow-up visits without requiring further investigation. Within this study cohort, the average follow-up time was 22 months. The average participant body mass index was 27.6. One iliac vein and IVC ultrasound was considered inadequate for follow-up evaluation and required further imaging. Conclusion: The use of iliac and IVC venous doppler ultrasound alone in the follow-up evaluation of iliac stent patency is effective and noninvasive and avoids unnecessary radiation exposure and cost.

研究目的本研究评估了单独使用髂静脉和 IVC 超声波对盆腔静脉疾病或慢性深静脉血栓引起的髂静脉闭塞患者的髂静脉支架进行随访评估的效果。方法:通过评估接受过髂静脉支架植入术的患者最近 100 次髂静脉和下腔静脉超声检查结果,进行了一项回顾性单点队列研究。纳入标准包括髂静脉支架置入史。排除标准包括未满 18 岁的患者、同一患者的重复患者以及超声检查时怀孕的患者。对彩色血流、灰度和相位的可视程度进行测定,并将其分为以下几类:完全、部分或无。此外,还对每张病历的外部压迫、支架内狭窄和进一步成像的要求进行了评估。结果:在本次审查评估的 100 例髂静脉和 IVC 超声波检查中,99 例超声波检查足以在随访时进行评估,无需进一步检查。在该研究队列中,平均随访时间为 22 个月。参与者的平均体重指数为 27.6。有一项髂静脉和 IVC 超声波检查被认为不足以进行随访评估,需要进行进一步的成像检查。结论仅使用髂静脉和 IVC 静脉多普勒超声来随访评估髂支架的通畅性是有效和无创的,并可避免不必要的辐射暴露和成本。
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引用次数: 0
Dermatophlebology: Understanding dermal responses to venous disease. 皮肤静脉学:了解皮肤对静脉疾病的反应。
Pub Date : 2025-03-01 Epub Date: 2024-08-22 DOI: 10.1177/02683555241239721
Ronald Bush

Dermatophlebology refers to the study of dermal alterations that occur with transmitted high venous pressure. These changes may range from telangiectasia, complex dermal vascular conditions, and all changes in Clinical Etiology Anatomical Pathophysiology classes IV-VI. Understanding the underlying pathophysiology is essential to treating the skin manifestations of venous disease.

皮肤血管病学是指研究高静脉压引起的真皮改变。这些变化包括毛细血管扩张、复杂的真皮血管状况以及临床病因解剖病理生理学 IV-VI 级的所有变化。了解潜在的病理生理学对于治疗静脉疾病的皮肤表现至关重要。
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引用次数: 0
Mechanochemical chemically assisted ablation of varicose veins for venous insufficiency: American vein and lymphatic society position statement. 针对静脉功能不全的曲张静脉机械化学辅助消融术:美国静脉与淋巴协会立场声明。
Pub Date : 2025-03-01 Epub Date: 2024-08-21 DOI: 10.1177/02683555241276554
John Blebea, Eri Fukaya, Keith S Moore, Fedor Lurie

Background: Mechanical occlusion chemically assisted ablation (MOCA) of incompetent saphenous veins has been utilized since its FDA approval in 2008. However, only recently have longer-term three and 5 year clinical follow up data become available. This updated information necessitates a societal update to guide treatment and ensure optimal patient outcomes. Method: The American Vein and Lymphatic Society convened an expert panel to write a Position Statement with explanations and recommendations for the appropriate use of MOCA for patients with venous insufficiency. Result: This Position Statement was produced by the expert panel with recommendations for appropriate use, treatment technique, outcomes review, and potential adverse events. These recommendations were reviewed, edited, and approved by the Guidelines Committee of the Society. Conclusions: MOCA is effective in alleviating symptoms and a safe treatment option for venous insufficiency. It obviates the need for tumescent anesthesia, has less procedural discomfort and lower risk of thermal nerve or skin injury. It may be used in both the below knee distal GSV as well as the SSV. However, it is associated with significantly lower rates of vessel closure and higher recanalization rates compared to both RFA and EVLA and is less cost effective than thermal techniques. It is an available option for those in whom thermal ablation is not suitable.

背景:自 2008 年获得美国食品及药物管理局批准以来,针对无功能隐静脉的机械闭塞化学辅助消融术(MOCA)一直在使用。然而,直到最近才有了三年和五年的长期临床随访数据。有必要对这些最新信息进行社会更新,以指导治疗并确保患者获得最佳疗效。方法:美国静脉和淋巴协会召集了一个专家小组,撰写了一份立场声明,对静脉功能不全患者如何适当使用 MOCA 做出了解释和建议。结果:专家小组撰写了这份立场声明,就适当使用、治疗技术、结果审查和潜在不良事件提出了建议。学会指南委员会对这些建议进行了审查、编辑和批准。结论:MOCA能有效缓解症状,是静脉功能不全的安全治疗方案。它无需进行肿胀麻醉,减少了手术过程中的不适感,降低了热神经或皮肤损伤的风险。它既可用于膝下远端 GSV,也可用于 SSV。不过,与 RFA 和 EVLA 相比,它的血管闭合率明显较低,再通率较高,而且成本效益低于热疗技术。对于那些不适合热消融的患者来说,这是一种可行的选择。
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引用次数: 0
Nonpelvic comorbid symptoms of 45 patients with pain of pelvic venous origin, before and after treatment. 45 名骨盆静脉源性疼痛患者治疗前后的非骨盆合并症状。
Pub Date : 2025-03-01 Epub Date: 2024-08-10 DOI: 10.1177/02683555241273109
Steven J Smith, B Holly Smith, Michael J Sichlau, Brenda Chen, Dacre Knight, Peter C Rowe

Objective: To report the prevalence and severity of nonpelvic symptoms for patients with venous-origin chronic pelvic pain (VO-CPP) and to describe outcomes after pelvic vein stenting and embolization.

Methods: We retrospectively reviewed outcomes of 45 women with VO-CPP who underwent treatment with iliac vein stenting and/or embolization. Patients completed symptom-severity questionnaires before and after treatment that assessed for pelvic pain, and multiple other symptoms, including brain fog, anxiety, depression, musculoskeletal pain, fatigue, migraines and more.

Results: Patient age ranged from 18 to 65 years. The prevalence of common symptoms was as follows: migraines, 69%; brain fog, 76%; anxiety attacks, 58%; excess sweating, 64%; hip pain, 73%; diarrhea, 62%; constipation, 76%; and abdominal bloating, 82%. After treatment, most symptom scores improved by more than 50%; exceptions were excessive sweating (41% improvement) and bloating (47% improvement). Prevalence of individual symptoms that bundle into POTS ranged from 29% to 76%, where symptom improvement ranged from 23% to 59% after treatment. Overlapping individual symptoms characteristic of fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) were present in 64% to 82% of patients and all improved by 49% to 63% after treatment.

Conclusions: Pelvic venous flow abnormality is linked causally to a spectrum of interrelated symptoms, of which many can be bundled into named syndromes of unknown cause. With catheter- based treatment of pelvic venous pooling, nonpelvic symptom and syndrome scores improved.

目的报告静脉源性慢性盆腔痛(VO-CPP)患者非盆腔症状的发生率和严重程度,并描述盆腔静脉支架植入术和栓塞术后的疗效:我们对 45 名接受髂静脉支架植入术和/或栓塞术治疗的 VO-CPP 女性患者的疗效进行了回顾性研究。患者在治疗前后填写了症状严重性问卷,评估盆腔疼痛和其他多种症状,包括脑雾、焦虑、抑郁、肌肉骨骼疼痛、疲劳、偏头痛等:患者年龄从 18 岁到 65 岁不等。常见症状的发生率如下:偏头痛,69%;脑雾,76%;焦虑发作,58%;多汗,64%;臀部疼痛,73%;腹泻,62%;便秘,76%;腹胀,82%。治疗后,大多数症状的评分都提高了 50%以上,但多汗(提高 41%)和腹胀(提高 47%)除外。与 POTS 相结合的个别症状发生率为 29% 至 76%,治疗后症状改善率为 23% 至 59%。64%至82%的患者存在纤维肌痛和肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)的重叠症状,治疗后症状改善率为49%至63%:结论:盆腔静脉血流异常与一系列相互关联的症状存在因果关系,其中许多症状可归纳为原因不明的综合征。通过导管治疗骨盆静脉积水,非骨盆症状和综合征评分均有所改善。
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引用次数: 0
Standardizing practice patterns for venous insufficiency ultrasound. 静脉功能不全超声波检查的标准化实践模式。
Pub Date : 2025-03-01 Epub Date: 2024-09-06 DOI: 10.1177/02683555241276556
Donna Kelly, Sherry Scovell

Background: This study aimed to evaluate the variability in practice patterns associated with the performance of duplex ultrasound (DUS) for venous insufficiency.

Methods: Sonographers participated in a survey regarding patient positioning and method of augmentation as well as the availability of ergonomic equipment for DUS.

Results: DUS was performed in RT position by 41% of sonographers versus standing position in 40%. In 18% of laboratories, if the RT position did not demonstrate reflux, the study was repeated in the standing position. An automated cuff inflation device was used as the primary method of augmentation in only 22% of practices.

Conclusions: There is a lack of standardization for the performance parameters of patient position and method of augmentation in VDU, which may lead to variation in the results between sonographers and institutions.

背景:本研究旨在评估与静脉功能不全的双相超声(DUS)检查相关的实践模式的变异性:本研究旨在评估与静脉功能不全的双工超声检查(DUS)相关的实践模式的差异性:方法:超声技师参与了一项关于患者体位、增强方法以及是否有符合人体工程学的 DUS 设备的调查:结果:41%的超声技师采用RT体位进行DUS检查,40%的超声技师采用站立体位。在 18% 的实验室中,如果 RT 体位未显示反流,则以站立位重复研究。只有 22% 的实验室将自动充气罩囊充气装置作为主要的增强方法:VDU中患者体位和扩容方法的性能参数缺乏标准化,这可能会导致超声技师和机构之间的结果存在差异。
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引用次数: 0
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Phlebology
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