Job demands and DHEA-S levels: a study on healthcare workers.

IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Occupational Medicine-Oxford Pub Date : 2024-05-09 DOI:10.1093/occmed/kqae017
F Marcatto, E Patriarca, D Bramuzzo, E Lucci, F Larese Filon
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Abstract

Background: The intricate interplay between work-related stress and its physiological impact has drawn extensive research attention. Dehydroepiandrosterone sulphate (DHEA-S) emerges as a potential biomarker reflecting stress-related endocrine changes.

Aims: This cross-sectional study aimed to examine the association between job demands and DHEA-S levels among healthcare workers. The study also explored potential correlations between DHEA-S levels and psychophysical symptoms commonly linked to work-related stress.

Methods: A sample of 488 healthcare workers from a local health authority participated. Job demands were measured using the Demands scale of the Health and Safety Management Standards Indicator Tool. DHEA-S levels and symptom prevalence were assessed through serum analysis and questionnaires, respectively.

Results: Workers exposed to high job demands exhibited significantly lower DHEA-S levels compared to those with low job demands. Psychophysical symptoms, including sleep disorders, depression, and headache, were more prevalent in the high-demands group. DHEA-S levels showed significant negative correlations with the prevalence of all considered symptoms.

Conclusions: The study shows the inverse relationship between job demands and DHEA-S levels among healthcare workers, indicating that high job demands correlate with reduced DHEA-S secretion and increased symptom prevalence. The findings suggest DHEA-S as a potential biomarker for assessing the physiological consequences of work-related stress. Proactive interventions in managing job demands are crucial for promoting employee well-being and productivity in demanding work environments. By recognizing DHEA-S as a stress biomarker, organizations can effectively address stress-related health risks and implement targeted interventions for enhancing employees' overall health and work performance.

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工作要求与 DHEA-S 水平:对医护人员的研究。
背景:与工作有关的压力及其生理影响之间错综复杂的相互作用引起了广泛的研究关注。硫酸脱氢表雄酮(DHEA-S)是反映与压力相关的内分泌变化的潜在生物标志物。研究还探讨了 DHEA-S 水平与通常与工作压力相关的心理物理症状之间的潜在关联:方法:来自一个地方卫生机构的 488 名医护人员参与了这项研究。工作要求采用健康与安全管理标准指标工具的要求量表进行测量。DHEA-S水平和症状发生率分别通过血清分析和问卷调查进行评估:结果:工作要求高的工人的 DHEA-S 水平明显低于工作要求低的工人。心理生理症状,包括睡眠障碍、抑郁和头痛,在高要求组中更为普遍。DHEA-S水平与所有症状的发生率呈显著负相关:研究表明,医护人员的工作要求与 DHEA-S 水平之间存在反比关系,表明高工作要求与 DHEA-S 分泌减少和症状发生率增加相关。研究结果表明,DHEA-S 是一种潜在的生物标志物,可用于评估与工作相关的压力所造成的生理后果。在要求苛刻的工作环境中,积极主动地干预工作需求管理对于促进员工身心健康和工作效率至关重要。通过认识到 DHEA-S 是一种压力生物标志物,企业可以有效地应对与压力相关的健康风险,并实施有针对性的干预措施,以提高员工的整体健康水平和工作绩效。
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来源期刊
Occupational Medicine-Oxford
Occupational Medicine-Oxford 医学-公共卫生、环境卫生与职业卫生
CiteScore
5.80
自引率
3.90%
发文量
120
审稿时长
4-8 weeks
期刊介绍: Occupational Medicine is an international peer-reviewed journal which provides vital information for the promotion of workplace health and safety. The key strategic aims of the journal are to improve the practice of occupational health professionals through continuing education and to raise the profile of occupational health with key stakeholders including policy makers and representatives of employers and employees. Topics covered include work-related injury and illness, accident and illness prevention, health promotion, occupational disease, health education, the establishment and implementation of health and safety standards, monitoring of the work environment, and the management of recognized hazards. Contributions are welcomed from practising occupational health professionals and research workers in related fields.
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