[Oral diseases and dementia].

Lakartidningen Pub Date : 2024-03-12
Kåre Buhlin, Maria Eriksdotter
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引用次数: 0

Abstract

The aging population makes the increase in cognitive disorders a challenge. One of the risk factors is old age, but also oral diseases, especially periodontitis, have been linked to an increased risk of dementia, especially Alzheimer's disease (AD), although research studies show varying correlations. Dental care utilization also decreases after a dementia diagnosis. The periodontal diseases are inflammatory disorders and common in the adult population. Periodontitis leads to loss of the supporting tissue of the tooth and, if untreated, to loss of teeth. Inflammation also plays a role in AD, the most common form of dementia. The reason for an association could be that periodontitis may lead to a spread of pro-inflammatory mediators and oral microorganisms to the brain. Another explanation suggests that chewing may stimulate nerve impulses and increase the blood flow to the brain. Fewer teeth could lead to less stimulation and reduced blood flow. In conclusion, oral diseases and dementia appear to be associated. Whether this connection constitutes a causal connection is more uncertain.

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[口腔疾病与痴呆症]。
人口老龄化使认知障碍的增加成为一项挑战。风险因素之一是老年,但口腔疾病,尤其是牙周炎,也与痴呆症,特别是阿尔茨海默病(AD)的风险增加有关,尽管研究显示出不同的相关性。痴呆症确诊后,牙科保健的使用率也会下降。牙周疾病是炎症性疾病,在成年人群中很常见。牙周炎会导致牙齿的支持组织丧失,如果不及时治疗,还会导致牙齿脱落。炎症在最常见的痴呆症--注意力缺失症中也扮演着重要角色。造成这种关联的原因可能是牙周炎可能导致促炎介质和口腔微生物扩散到大脑。另一种解释是,咀嚼可能会刺激神经冲动,增加流向大脑的血流量。牙齿减少可能导致刺激减少和血流量减少。总之,口腔疾病和痴呆症似乎有关联。但这种联系是否构成因果关系还不确定。
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来源期刊
Lakartidningen
Lakartidningen Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
134
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