Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and mice.

Cell metabolism Pub Date : 2024-05-07 Epub Date: 2024-03-11 DOI:10.1016/j.cmet.2024.02.008
Nathan H Witmer, Connor R Linzer, Ryan L Boudreau
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Abstract

Witmer et al. provide genomic and molecular evidence to demonstrate that Fndc5 (irisin myokine precursor protein) is translated in humans from an overlooked upstream ATG codon.

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在人和小鼠体内,Fndc5 从上游 ATG 起始密码子翻译并裂解产生鸢尾素肌动蛋白前体蛋白。
Witmer 等人提供了基因组和分子证据,证明 Fndc5(鸢尾素肌动蛋白前体蛋白)在人类中是通过被忽略的上游 ATG 密码子翻译的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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