Xiang-Da Li , Yan-Gang Cao , Yu-Han Zhang , Ying-Jie Ren , Meng-Nan Zeng , Yan-Ling Liu , Xu Chen , Xin-Yi Ma , Bing-Xian Zhao , Xiao-Ke Zheng , Wei-Sheng Feng
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引用次数: 0
Abstract
Two new undescribed compounds, jiofuran acid A (1) and 8′-hydroxyl episesaminone (2), together with seven known compounds (3–9) were isolated from the fresh roots of Zhongsheng No.1 Rehmannia glutinosa. Their structures were established by spectroscopic techniques (HR-ESI-MS, 1D NMR, 2D NMR), and absolute configurations were resolved by comparing their experimental and calculated ECD spectra. Bioassay results demonstrated compounds 1–3 exhibited the obvious anti-pulmonary fibrosis activity.
期刊介绍：
Phytochemistry Letters invites rapid communications on all aspects of natural product research including:
• Structural elucidation of natural products
• Analytical evaluation of herbal medicines
• Clinical efficacy, safety and pharmacovigilance of herbal medicines
• Natural product biosynthesis
• Natural product synthesis and chemical modification
• Natural product metabolism
• Chemical ecology
• Biotechnology
• Bioassay-guided isolation
• Pharmacognosy
• Pharmacology of natural products
• Metabolomics
• Ethnobotany and traditional usage
• Genetics of natural products
Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.
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