Evaluation of potential prevalence of onconeural antibodies in women with breast cancer.

Q3 Medicine Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI:10.36740/Merkur202401101
Patrycja Krolewska-Daszczynska, Marta Smycz-Kubanska, Celina Kruszniewska-Rajs, Jacek Kabut, Paweł Olczyk, Joanna Gola, Aleksandra Mielczarek-Palacz
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Abstract

Objective: Aim: To analyse onconeural antibodies in the blood serum of breast cancer patients without neurological symptoms..

Patients and methods: Materials and Methods: The study included 48 women with breast cancer. Paraneoplastic Neurologic Syndromes 12 Ag (IgG) Euroline by EUROIMMUN test was used to determine onconeural antibodies: anti-Hu, anti-Yo, anti-Ri, anti-CV2, anti-Ma/anti-Ta, anti-amphiphysin, anti-recoverin, anti-SOX1, anti-tytin, anti-zic4, anti-GAD65 and anti-Tr (DNER).

Results: Results: The conducted analysis revealed the presence of onconeural antibodies such as: anti-recoverin, anti-CV2, anti-Zic4, anti-SOX1, anti-MA2/Ta and antititin in blood serum of women with breast cancer.

Conclusion: Conclusions: Further analysis may allow the assessment of the possible clinical usefulness of these determinations.

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评估乳腺癌女性患者体内肿瘤细胞抗体的潜在流行率。
目的:分析无神经症状的乳腺癌患者血清中的肿瘤细胞抗体:目的:分析无神经系统症状的乳腺癌患者血清中的肿瘤抗体:材料与方法研究对象包括 48 名乳腺癌女性患者。采用EUROIMMUN测试法检测肿瘤神经综合征12Ag(IgG)Euroline,以确定肿瘤神经抗体:抗-Hu、抗-Yo、抗-Ri、抗-CV2、抗-Ma/抗-Ta、抗-phiphysin、抗-recoverin、抗-SOX1、抗-tytin、抗-zic4、抗-GAD65和抗-Tr(DNER):结果:结果:分析结果显示,乳腺癌女性患者血清中存在抗复原素、抗CV2、抗Zic4、抗SOX1、抗MA2/Ta和抗酪蛋白抗体:结论通过进一步分析,可以评估这些检测结果的临床实用性。
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Polski Merkuriusz Lekarski
Polski Merkuriusz Lekarski Medicine-Medicine (all)
CiteScore
1.90
自引率
0.00%
发文量
84
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