A case of concomitant juvenile idiopathic arthritis (JIA) and paediatric-onset multiple sclerosis (POMS) – treatment with secukinumab and dimethyl fumarate followed by ofatumumab

Aleksandra Jartych, A. Jamróz-Wiśniewska, Konrad Rejdak, Weronika Kleszczyńska, Michał Kaczor
{"title":"A case of concomitant juvenile idiopathic arthritis (JIA) and paediatric-onset multiple sclerosis (POMS) – treatment with secukinumab and dimethyl fumarate followed by ofatumumab","authors":"Aleksandra Jartych, A. Jamróz-Wiśniewska, Konrad Rejdak, Weronika Kleszczyńska, Michał Kaczor","doi":"10.26444/jpccr/185685","DOIUrl":null,"url":null,"abstract":"The aim of this case report is to highlight new possible treatment methods for concomitant juvenile idiopathic arthritis and multiple sclerosis in young patients. Promising results of using ofatumumab, secukinumab and dimethyl fumarate, both in the clinical case of a 22-year-old patient and mentioned literature, allows the belief that there is a chance for improving the quality of life of those who suffer from coexisting autoimmune diseases. However, it is crucial to perform further research in terms of the necessity and safety of the mentioned therapies, especially in the paediatric population, among whom there often exists difficulty in using treatment not registered for under-aged patients. Furthermore, the higher risk of side-effects caused by combined treatment of two autoimmune diseases should also be taken into consideration.","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"53 7","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pre-Clinical and Clinical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26444/jpccr/185685","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

The aim of this case report is to highlight new possible treatment methods for concomitant juvenile idiopathic arthritis and multiple sclerosis in young patients. Promising results of using ofatumumab, secukinumab and dimethyl fumarate, both in the clinical case of a 22-year-old patient and mentioned literature, allows the belief that there is a chance for improving the quality of life of those who suffer from coexisting autoimmune diseases. However, it is crucial to perform further research in terms of the necessity and safety of the mentioned therapies, especially in the paediatric population, among whom there often exists difficulty in using treatment not registered for under-aged patients. Furthermore, the higher risk of side-effects caused by combined treatment of two autoimmune diseases should also be taken into consideration.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
一例并发幼年特发性关节炎(JIA)和儿童型多发性硬化症(POMS)的病例--先用secukinumab和富马酸二甲酯治疗,再用ofatumumab治疗
本病例报告旨在强调治疗年轻患者并发幼年特发性关节炎和多发性硬化症的新方法。在一名 22 岁患者的临床病例和文献中,使用 ofatumumab、secukinumab 和富马酸二甲酯都取得了令人鼓舞的结果,这让人们相信,并发自身免疫性疾病患者的生活质量有可能得到改善。然而,对上述疗法的必要性和安全性进行进一步研究至关重要,尤其是在儿科人群中,因为他们在使用未注册的未成年患者治疗方法时往往会遇到困难。此外,还应考虑到合并治疗两种自身免疫性疾病所导致的副作用风险更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
25
审稿时长
12 weeks
期刊最新文献
The role of THC and CBD in dentistry – a review of impacts on oral health Distant metastases from the uterine leiomyoma – case report of a pulmonary benign metastasizing leiomyoma Penetrating eye injuries- case description Chronic kidney disease and obesity - pathomechanisms and treatment – literature review Piriformis syndrome – anatomical causes. Diagnosis and treatment
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1