ASSESSMENT OF ANTERIOR CHAMBER ANGLE ON ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY IN PATIENTS WITH ANGLE CLOSURE GLAUCOMA AND ANGLE CLOSURE SUSPECTS

SA Bhutto, AA Leghari, NA Katpar, Z. Gopang, Dyd Shaikh, PA Gul
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Abstract

The objective of this cross-sectional study was to determine the anterior chamber angle using anterior segment optical coherence tomography (AS-OCT) in patients diagnosed with angle closure glaucoma and angle closure suspects. The research was conducted at Shaheed Mohtarma Benazir Bhutto Medical University Larkana, spanning from March 3, 2022, to June 30, 2023. Patients meeting the inclusion criteria and diagnosed with primary angle-closure glaucoma (PACG) were enrolled in the study after obtaining informed consent. The procedure, risks, and benefits of the study were explained to the patients before obtaining consent. AS-OCT was utilized to evaluate patients suspected of primary angle closure and those with confirmed primary angle closure. The results revealed a mean age of 56.21 ± 12.31 years among the study participants, with a confidence interval of 55.04 to 57.38. The mean duration of primary angle closure glaucoma was 22.52 ± 10.98 months, with a confidence interval of 21.47 to 23.57. Of the 423 patients included in the study, 219 (52%) were male, and 204 (48%) were female. Primary angle closure suspect and primary angle closure were observed in 47 (11%) and 44 (10%) patients, respectively. In conclusion, older age, higher central corneal thickness (CCT), and shorter axial length or presence of hyperopia were identified as important independent predictors of suspicion of primary angle closure and primary angle closure. These findings underscore the significance of thorough assessment and monitoring of these parameters in patients at risk of angle closure glaucoma.
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通过前节光学相干断层扫描评估闭角型青光眼患者和闭角型青光眼疑似患者的前房角
这项横断面研究的目的是利用前节光学相干断层扫描(AS-OCT)确定被诊断为闭角型青光眼和闭角型青光眼疑似患者的前房角。研究于 2022 年 3 月 3 日至 2023 年 6 月 30 日在拉尔卡纳沙希德-莫赫塔马-贝娜齐尔-布托医科大学(Shaheed Mohtarma Benazir Bhutto Medical University Larkana)进行。符合纳入标准并确诊为原发性闭角型青光眼(PACG)的患者在获得知情同意后被纳入研究。在获得同意之前,已向患者解释了研究的程序、风险和益处。利用 AS-OCT 对疑似原发性闭角和确诊为原发性闭角的患者进行评估。结果显示,研究参与者的平均年龄为(56.21 ± 12.31)岁,置信区间为 55.04 至 57.38 岁。原发性闭角型青光眼的平均病程为(22.52 ± 10.98)个月,置信区间为 21.47 至 23.57 个月。在研究的 423 名患者中,219 名(52%)为男性,204 名(48%)为女性。分别有 47 名(11%)和 44 名(10%)患者出现原发性闭角怀疑和原发性闭角。总之,年龄较大、角膜中央厚度(CCT)较高、轴向长度较短或存在远视被认为是原发性角膜闭合怀疑和原发性角膜闭合的重要独立预测因素。这些发现强调了对有闭角型青光眼风险的患者进行全面评估和监测这些参数的重要性。
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