Pub Date : 2024-08-08DOI: 10.54112/bcsrj.v2024i1.999
H. Jamil, R. Zahid, H. Waheed, A. Aslam, S. Khuwaja
Postoperative pain management is a critical aspect of care in the postoperative unit. While various analgesic drugs are commonly used, the role of preoperative counseling regarding the procedure and its potential outcomes is gaining recognition for its importance. However, there is limited research exploring this aspect. Objective: To compare the mean pain scores after preoperative counseling versus no counseling in patients undergoing elective surgery. Methods: This randomized controlled trial was conducted in the Department of Anaesthesiology, Hameed Latif Hospital, Lahore, from 15th May 2019 to 15th November 2019. Sixty patients aged 20-50, of either gender, undergoing general surgery under general anesthesia with ASA class I/II, were included. Patients were divided into two groups: those who received preoperative counseling (group A) and those who did not (group B). Preoperative counseling included information on the type of surgery, duration, possible complications, degree of pain, and its management. Postoperative pain was assessed using the Visual Analogue Scale (VAS) 6 hours after surgery. Statistical analysis was performed to compare the mean pain scores between the two groups. Results: The study included 60 patients, 19 males in group A and 20 in group B. The mean age was 36.47±8.32 years in group A and 36.93±8.83 years in group B (p=0.79). The mean postoperative pain score on VAS was 3.43±1.07 in the group that received preoperative counseling (group A) and 5.03±1.61 in the group without counseling (group B) (p=0.03). Pain scores in males were 3.31±0.83 in group A and 4.97±1.47 in group B (p=0.01). In females, scores were 3.49±0.97 in group A and 5.53±1.73 in group B (p=0.03). In the 20-34 age group, the pain score was 3.38±0.97 in group A and 4.99±1.21 in group B (p=0.02), and in the 35-50 age group, the score was 3.44±1.05 in group A and 5.05±1.29 in group B (p=0.03). VAS scores were 3.46±1.07 in ASA class I and 3.27±0.95 in ASA class II in group A, compared to 5.03±1.63 and 5.03±1.45 in group B, respectively (p=0.03 each). Pain scores were also significantly better in group A across different educational statuses. Conclusion: Preoperative counseling substantially reduces postoperative pain scores as measured by the Visual Analogue Scale, compared to no counseling. This difference is statistically significant across various demographic and clinical subgroups.
术后疼痛管理是术后病房护理的一个重要方面。虽然常用的镇痛药物种类繁多，但就手术过程及其潜在结果进行术前咨询的重要性正日益得到认可。然而，对这方面的研究还很有限。研究目的比较接受择期手术的患者在接受术前咨询和未接受咨询后的平均疼痛评分。方法：这项随机对照试验于 2019 年 5 月 15 日至 2019 年 11 月 15 日在拉合尔 Hameed Latif 医院麻醉科进行。纳入的 60 名患者年龄在 20-50 岁之间，性别不限，在全身麻醉下接受普通手术，ASA 分级为 I/II 级。患者分为两组：接受术前咨询的患者（A 组）和未接受术前咨询的患者（B 组）。术前咨询内容包括手术类型、持续时间、可能出现的并发症、疼痛程度及其处理方法。术后 6 小时后，使用视觉模拟量表（VAS）对术后疼痛进行评估。对两组患者的平均疼痛评分进行了统计分析比较。研究结果A组患者的平均年龄为（36.47±8.32）岁，B组患者的平均年龄为（36.93±8.83）岁（P=0.79）。接受术前咨询组（A 组）术后疼痛 VAS 平均评分为（3.43±1.07）分，未接受咨询组（B 组）术后疼痛 VAS 平均评分为（5.03±1.61）分（P=0.03）。A 组男性的疼痛评分为 3.31±0.83，B 组为 4.97±1.47（P=0.01）。女性的疼痛评分在 A 组为 3.49±0.97，在 B 组为 5.53±1.73（P=0.03）。在 20-34 岁年龄组中，A 组的疼痛评分为 3.38±0.97，B 组为 4.99±1.21（P=0.02）；在 35-50 岁年龄组中，A 组的疼痛评分为 3.44±1.05，B 组为 5.05±1.29（P=0.03）。A 组 ASA I 级的 VAS 评分为 3.46±1.07，ASA II 级的 VAS 评分为 3.27±0.95，而 B 组分别为 5.03±1.63、5.03±1.45（P=0.03）。在不同的教育状况下，A 组的疼痛评分也明显更好。结论与不提供咨询相比，术前咨询可大幅降低术后疼痛评分（以视觉模拟量表测量）。在不同的人口统计学和临床分组中，这一差异具有统计学意义。
{"title":"DOES PREOPERATIVE COUNSELLING HELP IMPROVE PATIENTS’ SATISFACTION WITH PAIN MANAGEMENT IN POSTOPERATIVE PERIOD","authors":"H. Jamil, R. Zahid, H. Waheed, A. Aslam, S. Khuwaja","doi":"10.54112/bcsrj.v2024i1.999","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.999","url":null,"abstract":"Postoperative pain management is a critical aspect of care in the postoperative unit. While various analgesic drugs are commonly used, the role of preoperative counseling regarding the procedure and its potential outcomes is gaining recognition for its importance. However, there is limited research exploring this aspect. Objective: To compare the mean pain scores after preoperative counseling versus no counseling in patients undergoing elective surgery. Methods: This randomized controlled trial was conducted in the Department of Anaesthesiology, Hameed Latif Hospital, Lahore, from 15th May 2019 to 15th November 2019. Sixty patients aged 20-50, of either gender, undergoing general surgery under general anesthesia with ASA class I/II, were included. Patients were divided into two groups: those who received preoperative counseling (group A) and those who did not (group B). Preoperative counseling included information on the type of surgery, duration, possible complications, degree of pain, and its management. Postoperative pain was assessed using the Visual Analogue Scale (VAS) 6 hours after surgery. Statistical analysis was performed to compare the mean pain scores between the two groups. Results: The study included 60 patients, 19 males in group A and 20 in group B. The mean age was 36.47±8.32 years in group A and 36.93±8.83 years in group B (p=0.79). The mean postoperative pain score on VAS was 3.43±1.07 in the group that received preoperative counseling (group A) and 5.03±1.61 in the group without counseling (group B) (p=0.03). Pain scores in males were 3.31±0.83 in group A and 4.97±1.47 in group B (p=0.01). In females, scores were 3.49±0.97 in group A and 5.53±1.73 in group B (p=0.03). In the 20-34 age group, the pain score was 3.38±0.97 in group A and 4.99±1.21 in group B (p=0.02), and in the 35-50 age group, the score was 3.44±1.05 in group A and 5.05±1.29 in group B (p=0.03). VAS scores were 3.46±1.07 in ASA class I and 3.27±0.95 in ASA class II in group A, compared to 5.03±1.63 and 5.03±1.45 in group B, respectively (p=0.03 each). Pain scores were also significantly better in group A across different educational statuses. Conclusion: Preoperative counseling substantially reduces postoperative pain scores as measured by the Visual Analogue Scale, compared to no counseling. This difference is statistically significant across various demographic and clinical subgroups.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141928927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.54112/bcsrj.v2024i1.986
I. Rasool, K. Hussain, MA Ameen, A. Batool, M. Anam, A. Aziz, A. Hussain, MT Mahmood, Z. Maqsood, RT Ahmad, RA Samad
The study was conducted to check the impact of variable date of sowing for climate resilience in two consecutive years 2021-2022 and 2022-2023 at Faisalabad. Three different dates of sowing 25th of October, 10th, and 20th of November were selected for screening of sixteen Desi chickpea, genotypes, and commercial variety Bittal-2016 as check. Data were recorded for days to 50% flowering, plant height, primary and secondary branches, pods per plant, 100-grain weight, and grain yield kg/ha. The highest grain yield per ha in both years was produced by D-20004 and D-20007. The comparison of sowing dates manifested that on 25th October the plant health remained good and was less affected by climate and produced enhanced grain yield. On the 10th of November and 20th of November, plant growth remained stunted and bear the low number of pods per plant ultimately producing a low yield. The selected lines can be used in breeding programs for the development of climate-resilient chickpea genotypes.
{"title":"EVALUATION OF CHICKPEA VARIETIES FOR CLIMATE RESILIENCE AND YIELD STABILITY AT DIFFERENT PLANTING DATES","authors":"I. Rasool, K. Hussain, MA Ameen, A. Batool, M. Anam, A. Aziz, A. Hussain, MT Mahmood, Z. Maqsood, RT Ahmad, RA Samad","doi":"10.54112/bcsrj.v2024i1.986","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.986","url":null,"abstract":"The study was conducted to check the impact of variable date of sowing for climate resilience in two consecutive years 2021-2022 and 2022-2023 at Faisalabad. Three different dates of sowing 25th of October, 10th, and 20th of November were selected for screening of sixteen Desi chickpea, genotypes, and commercial variety Bittal-2016 as check. Data were recorded for days to 50% flowering, plant height, primary and secondary branches, pods per plant, 100-grain weight, and grain yield kg/ha. The highest grain yield per ha in both years was produced by D-20004 and D-20007. The comparison of sowing dates manifested that on 25th October the plant health remained good and was less affected by climate and produced enhanced grain yield. On the 10th of November and 20th of November, plant growth remained stunted and bear the low number of pods per plant ultimately producing a low yield. The selected lines can be used in breeding programs for the development of climate-resilient chickpea genotypes.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.54112/bcsrj.v2024i1.982
I. Hussain, S. Khan, FR KHAN, K. Aslam
Percutaneous coronary intervention (PCI) is widely used to treat coronary artery disease (CAD), particularly in patients with acute coronary syndromes. Dual antiplatelet therapy (DAPT), which includes aspirin and a P2Y12 inhibitor such as clopidogrel, ticagrelor, or prasugrel, is the standard post-PCI treatment to prevent thrombotic complications. Despite the benefits of DAPT, its safety and efficacy in the Pakistani population, which has a high prevalence of CAD, are not well-documented. Objective: This study aimed to evaluate the safety and efficacy of DAPT in Pakistani patients undergoing PCI by measuring the incidence of stent thrombosis, bleeding complications, and major adverse cardiac events (MACE) over a 12-month follow-up period. Methods: This prospective observational study was conducted from January 2022 to December 2023 across three centers: Lady Reading Hospital Peshawar, Mardan Medical Complex, and Hayatabad Medical Complex. The study included 300 adult patients scheduled for PCI. Participants received DAPT, consisting of aspirin and a P2Y12 inhibitor, before PCI and continued for at least 12 months post-procedure. Primary outcomes were the incidence of stent thrombosis, bleeding complications, and MACE. Secondary outcomes included improved left ventricular ejection fraction (LVEF), exercise tolerance, and angina symptoms. Data were analyzed using SPSS version 26.0. Results: The mean age of participants was 60 ± 10 years, with 65% male. The overall incidence of stent thrombosis was 3%, bleeding complications occurred 8%, and MACE was observed in 15% of patients. LVEF improved from 42% ± 8% pre-procedure to 50% ± 7% post-procedure (p < 0.001). The six-minute walk test distance increased from 320 ± 55 meters pre-procedure to 370 ± 50 meters post-procedure (p < 0.01). The frequency of angina episodes decreased from 4.2 ± 1.5 to 1.7 ± 0.9 per week (p < 0.001). Conclusion: DAPT significantly improves clinical outcomes in Pakistani patients undergoing PCI, enhancing LVEF and exercise tolerance and reducing angina episodes. However, the risk of bleeding complications necessitates careful patient management. These findings support the continued use of DAPT in this population, emphasizing the need for individualized treatment plans and continuous monitoring.
{"title":"SAFETY AND EFFICACY OF DUAL ANTIPLATELET THERAPY IN PAKISTANI PATIENTS UNDERGOING PCI: A MULTICENTER STUDY","authors":"I. Hussain, S. Khan, FR KHAN, K. Aslam","doi":"10.54112/bcsrj.v2024i1.982","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.982","url":null,"abstract":"Percutaneous coronary intervention (PCI) is widely used to treat coronary artery disease (CAD), particularly in patients with acute coronary syndromes. Dual antiplatelet therapy (DAPT), which includes aspirin and a P2Y12 inhibitor such as clopidogrel, ticagrelor, or prasugrel, is the standard post-PCI treatment to prevent thrombotic complications. Despite the benefits of DAPT, its safety and efficacy in the Pakistani population, which has a high prevalence of CAD, are not well-documented. Objective: This study aimed to evaluate the safety and efficacy of DAPT in Pakistani patients undergoing PCI by measuring the incidence of stent thrombosis, bleeding complications, and major adverse cardiac events (MACE) over a 12-month follow-up period. Methods: This prospective observational study was conducted from January 2022 to December 2023 across three centers: Lady Reading Hospital Peshawar, Mardan Medical Complex, and Hayatabad Medical Complex. The study included 300 adult patients scheduled for PCI. Participants received DAPT, consisting of aspirin and a P2Y12 inhibitor, before PCI and continued for at least 12 months post-procedure. Primary outcomes were the incidence of stent thrombosis, bleeding complications, and MACE. Secondary outcomes included improved left ventricular ejection fraction (LVEF), exercise tolerance, and angina symptoms. Data were analyzed using SPSS version 26.0. Results: The mean age of participants was 60 ± 10 years, with 65% male. The overall incidence of stent thrombosis was 3%, bleeding complications occurred 8%, and MACE was observed in 15% of patients. LVEF improved from 42% ± 8% pre-procedure to 50% ± 7% post-procedure (p < 0.001). The six-minute walk test distance increased from 320 ± 55 meters pre-procedure to 370 ± 50 meters post-procedure (p < 0.01). The frequency of angina episodes decreased from 4.2 ± 1.5 to 1.7 ± 0.9 per week (p < 0.001). Conclusion: DAPT significantly improves clinical outcomes in Pakistani patients undergoing PCI, enhancing LVEF and exercise tolerance and reducing angina episodes. However, the risk of bleeding complications necessitates careful patient management. These findings support the continued use of DAPT in this population, emphasizing the need for individualized treatment plans and continuous monitoring.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-14DOI: 10.54112/bcsrj.v2024i1.959
A. Farooqi, F. Zaheer, S. Salman, .. Sadia, S. Shaikh, S. Rimsha
Ingrown toenail (onychocryptosis) is a common and painful condition often requiring surgical intervention. Adequate local anaesthesia is crucial for patient comfort and surgical success. However, the optimal anaesthetic technique for this procedure remains debated. Objectives: This study aimed to evaluate and compare the anaesthetic efficacy, patient comfort, onset and duration of anaesthesia, and occurrence of complications between the V-block and H-block techniques during surgical procedures for ingrown toenail removal. Methods: After ethical approval, an open-label randomised control trial was conducted at Ruth PFAU Civil Hospital, Dow University of Health Sciences, Karachi. One hundred eighty-eight patients, aged 18 and above, with type II, III, and IV onychocryptosis were included. Patients were randomly assigned to either Group A (H-technique, n=94) or Group B (V-technique, n=94). Local anaesthesia was administered using 5 ml of 2% Xylocaine diluted in 5 ml of distilled water. Pain severity, numbness, and loss of sensation were assessed at 2, 5, and 10 minutes post-injection. Data were analysed using SPSS version 26. Results: Group A (H-technique) had a significantly younger average age (35.12±9.8 years) compared to Group B (39.77±13.01 years). Gender distribution differed significantly, but weight did not. At 2 minutes, Group B reported more pain (90% vs. 86.5%, P=0.045). At 5 and 10 minutes, Group B showed higher numbness and loss of sensation, indicating more comprehensive anaesthesia. Efficacy at 10 minutes was higher in Group B (44% vs. 39%, P=0.045), with similar trends at 20 minutes but no significant difference. Conclusion: The V-block technique offers rapid onset and effective pain relief for routine procedures, while the H-block technique provides more comprehensive and sustained anaesthesia for complex surgeries. The selection of anaesthetic techniques should be based on the surgical context to optimise patient outcomes. Further research is recommended to enhance these techniques' efficacy and minimise complications.
趾甲内生（onychocryptosis）是一种常见的疼痛症状，通常需要手术治疗。充分的局部麻醉对患者的舒适度和手术的成功至关重要。然而，该手术的最佳麻醉技术仍存在争议。研究目的本研究旨在评估和比较 V 型阻滞和 H 型阻滞技术在内生趾甲切除手术中的麻醉效果、患者舒适度、麻醉开始时间和持续时间以及并发症发生率。研究方法经伦理批准后，在卡拉奇陶尔健康科学大学鲁斯 PFAU 民用医院进行了一项开放标签随机对照试验。188名年龄在18岁及以上的II型、III型和IV型甲沟炎患者被纳入其中。患者被随机分配到 A 组（H 技术，94 人）或 B 组（V 技术，94 人）。使用 5 毫升 2% 的氟氯卡因稀释在 5 毫升蒸馏水中进行局部麻醉。在注射后 2 分钟、5 分钟和 10 分钟对疼痛严重程度、麻木和感觉丧失进行评估。数据使用 SPSS 26 版进行分析。结果甲组（H 技术）的平均年龄（35.12±9.8 岁）明显小于乙组（39.77±13.01 岁）。性别分布有明显差异，但体重没有差异。2 分钟时，B 组报告的疼痛程度更高（90% 对 86.5%，P=0.045）。5 分钟和 10 分钟时，B 组麻木感和感觉丧失程度更高，表明麻醉更全面。10 分钟时，B 组的疗效更高（44% 对 39%，P=0.045），20 分钟时的趋势相似，但无显著差异。结论V 型阻滞技术可为常规手术提供快速起效和有效的镇痛效果，而 H 型阻滞技术可为复杂手术提供更全面和持续的麻醉效果。麻醉技术的选择应以手术环境为基础，以优化患者的治疗效果。建议进一步开展研究，以提高这些技术的功效并将并发症降至最低。
{"title":"A COMPARATIVE STUDY OF ANESTHETIC BLOCK TECHNIQUES (V-BLOCK VS. H-BLOCK) FOR REMOVAL OF INGROWN TOENAIL","authors":"A. Farooqi, F. Zaheer, S. Salman, .. Sadia, S. Shaikh, S. Rimsha","doi":"10.54112/bcsrj.v2024i1.959","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.959","url":null,"abstract":"Ingrown toenail (onychocryptosis) is a common and painful condition often requiring surgical intervention. Adequate local anaesthesia is crucial for patient comfort and surgical success. However, the optimal anaesthetic technique for this procedure remains debated. Objectives: This study aimed to evaluate and compare the anaesthetic efficacy, patient comfort, onset and duration of anaesthesia, and occurrence of complications between the V-block and H-block techniques during surgical procedures for ingrown toenail removal. Methods: After ethical approval, an open-label randomised control trial was conducted at Ruth PFAU Civil Hospital, Dow University of Health Sciences, Karachi. One hundred eighty-eight patients, aged 18 and above, with type II, III, and IV onychocryptosis were included. Patients were randomly assigned to either Group A (H-technique, n=94) or Group B (V-technique, n=94). Local anaesthesia was administered using 5 ml of 2% Xylocaine diluted in 5 ml of distilled water. Pain severity, numbness, and loss of sensation were assessed at 2, 5, and 10 minutes post-injection. Data were analysed using SPSS version 26. Results: Group A (H-technique) had a significantly younger average age (35.12±9.8 years) compared to Group B (39.77±13.01 years). Gender distribution differed significantly, but weight did not. At 2 minutes, Group B reported more pain (90% vs. 86.5%, P=0.045). At 5 and 10 minutes, Group B showed higher numbness and loss of sensation, indicating more comprehensive anaesthesia. Efficacy at 10 minutes was higher in Group B (44% vs. 39%, P=0.045), with similar trends at 20 minutes but no significant difference. Conclusion: The V-block technique offers rapid onset and effective pain relief for routine procedures, while the H-block technique provides more comprehensive and sustained anaesthesia for complex surgeries. The selection of anaesthetic techniques should be based on the surgical context to optimise patient outcomes. Further research is recommended to enhance these techniques' efficacy and minimise complications.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-13DOI: 10.54112/bcsrj.v2024i1.983
T. Shah, HR Vishno, SM Shah, R. Ullah
Coronary artery disease (CAD) is a major global killer. Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) has improved CAD treatment. However, in-stent restenosis (ISR) remains a significant issue, especially for diabetic patients. Objective: This study aimed to compare ISR rates between diabetic and non-diabetic patients after PCI in a Pakistani hospital. Methods: We conducted a cross-sectional survey at Hayatabad Medical Complex, Peshawar, from January to December 2023. The study involved 273 patients aged 40-85 who underwent PCI with DES. Participants were split into diabetic and non-diabetic groups. Those with chronic kidney disease, previous coronary artery bypass graft surgery, or incomplete follow-up data were excluded. Data were gathered from medical records. ISR was marked by a luminal diameter reduction of more than 50% within the stent or 5 mm of its edges. We used chi-square tests and logistic regression for analysis, employing SPSS version 26.0. Results: The ISR rate was 23% overall. Diabetic patients showed a higher ISR rate (30%) than non-diabetic patients (16%). Logistic regression revealed diabetes (OR = 2.1, 95% CI: 1.3-3.2, p < 0.01), hypertension (OR = 1.8, 95% CI: 1.1-2.9, p < 0.05), and smoking (OR = 1.6, 95% CI: 1.0-2.5, p < 0.05) as significant predictors of ISR. Conclusion: This study highlights a higher ISR incidence in diabetic patients post-PCI. It underscores the need for meticulous monitoring and tailored strategies for this high-risk group. Managing hypertension, smoking, and dyslipidemia is essential to lower ISR rates and enhance outcomes.
{"title":"COMPARATIVE ANALYSIS OF IN-STENT RESTENOSIS IN DIABETIC AND NON-DIABETIC PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION IN PAKISTAN","authors":"T. Shah, HR Vishno, SM Shah, R. Ullah","doi":"10.54112/bcsrj.v2024i1.983","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.983","url":null,"abstract":"Coronary artery disease (CAD) is a major global killer. Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) has improved CAD treatment. However, in-stent restenosis (ISR) remains a significant issue, especially for diabetic patients. Objective: This study aimed to compare ISR rates between diabetic and non-diabetic patients after PCI in a Pakistani hospital. Methods: We conducted a cross-sectional survey at Hayatabad Medical Complex, Peshawar, from January to December 2023. The study involved 273 patients aged 40-85 who underwent PCI with DES. Participants were split into diabetic and non-diabetic groups. Those with chronic kidney disease, previous coronary artery bypass graft surgery, or incomplete follow-up data were excluded. Data were gathered from medical records. ISR was marked by a luminal diameter reduction of more than 50% within the stent or 5 mm of its edges. We used chi-square tests and logistic regression for analysis, employing SPSS version 26.0. Results: The ISR rate was 23% overall. Diabetic patients showed a higher ISR rate (30%) than non-diabetic patients (16%). Logistic regression revealed diabetes (OR = 2.1, 95% CI: 1.3-3.2, p < 0.01), hypertension (OR = 1.8, 95% CI: 1.1-2.9, p < 0.05), and smoking (OR = 1.6, 95% CI: 1.0-2.5, p < 0.05) as significant predictors of ISR. Conclusion: This study highlights a higher ISR incidence in diabetic patients post-PCI. It underscores the need for meticulous monitoring and tailored strategies for this high-risk group. Managing hypertension, smoking, and dyslipidemia is essential to lower ISR rates and enhance outcomes.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-13DOI: 10.54112/bcsrj.v2024i1.961
A. Farooqi, F. Zaheer, S. Abbas, S. Shaikh, .. Sadia, S. Salman
This study aimed to evaluate the effectiveness of chymotrypsin and trypsin in improving post-operative wound management outcomes in patients undergoing inguinal hernia repair. Methods: An open-label randomised control trial was conducted at the Department of General Surgery, Ruth PFAU Civil Hospital Dow University of Health Sciences, Karachi. A total of 48 patients undergoing elective inguinal hernia surgery were included and randomly assigned to either Group A (placebo) or Group B (intervention). Group B received chymotrypsin (6 mg) and trypsin (1 mg) post-operatively for seven days. Outcome measures included oedema, hematoma, seroma, surgical site infection (SSI), pain scores, and duration of hospital stay. Data were analysed using SPSS version 21, with significance at P ≤ 0.05. Results: The mean age was higher in Group B (38.5 ± 11.1 years) than in Group A (33.91 ± 8.9 years) (P = 0.01). Group B had significantly lower incidences of oedema (42% vs 71%, P = 0.042), hematoma (21% vs 42%, P = 0.009), and seroma (11 vs 20, P = 0.007) compared to Group A. Although SSI rates were lower in Group B (25%) compared to Group A (50%), this difference was not statistically significant (P = 0.068). Pain scores were significantly lower in Group B (2.625 ± 0.7) compared to Group A (5.125 ± 0.7) (P < 0.0001). The duration of hospital stay was also shorter in Group B (3.75 ± 0.8 days) than in Group A (6.9 ± 1.08 days) (P < 0.0001). Conclusion: Chymotrypsin and trypsin significantly enhance post-operative recovery by reducing oedema, hematoma, seroma, pain scores, and hospital stay duration in inguinal hernia repair patients. These findings support incorporating enzymatic agents into post-operative care protocols to improve patient outcomes.
本研究旨在评估糜蛋白酶和胰蛋白酶在改善腹股沟疝修补术患者术后伤口管理效果方面的有效性。研究方法卡拉奇陶夫卫生科学大学 Ruth PFAU 民用医院普外科进行了一项开放标签随机对照试验。共纳入 48 名接受腹股沟疝气择期手术的患者，并随机分配到 A 组（安慰剂）或 B 组（干预）。B 组术后接受糜蛋白酶（6 毫克）和胰蛋白酶（1 毫克）治疗，为期 7 天。结果测量包括水肿、血肿、血清肿、手术部位感染（SSI）、疼痛评分和住院时间。数据采用 SPSS 21 版进行分析，P ≤ 0.05 为显著性差异。结果B 组的平均年龄（38.5 ± 11.1 岁）高于 A 组（33.91 ± 8.9 岁）（P = 0.01）。与 A 组相比，B 组的水肿（42% 对 71%，P = 0.042）、血肿（21% 对 42%，P = 0.009）和血清肿（11 对 20，P = 0.007）发生率明显较低。虽然 B 组的 SSI 发生率（25%）低于 A 组（50%），但差异无统计学意义（P = 0.068）。B 组的疼痛评分（2.625 ± 0.7）明显低于 A 组（5.125 ± 0.7）（P < 0.0001）。B 组的住院时间（3.75 ± 0.8 天）也比 A 组（6.9 ± 1.08 天）短（P < 0.0001）。结论糜蛋白酶和胰蛋白酶可减少腹股沟疝修补术患者的水肿、血肿、血清肿、疼痛评分和住院时间，从而明显促进术后恢复。这些研究结果支持将酶制剂纳入术后护理方案，以改善患者的治疗效果。
{"title":"ROLE OF CHYMOTRYPSIN IN POST-OPERATIVE WOUND MANAGEMENT IN PATIENTS UNDERGOING ELECTIVE INGUINAL HERNIA REPAIR SURGERIES","authors":"A. Farooqi, F. Zaheer, S. Abbas, S. Shaikh, .. Sadia, S. Salman","doi":"10.54112/bcsrj.v2024i1.961","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.961","url":null,"abstract":"This study aimed to evaluate the effectiveness of chymotrypsin and trypsin in improving post-operative wound management outcomes in patients undergoing inguinal hernia repair. Methods: An open-label randomised control trial was conducted at the Department of General Surgery, Ruth PFAU Civil Hospital Dow University of Health Sciences, Karachi. A total of 48 patients undergoing elective inguinal hernia surgery were included and randomly assigned to either Group A (placebo) or Group B (intervention). Group B received chymotrypsin (6 mg) and trypsin (1 mg) post-operatively for seven days. Outcome measures included oedema, hematoma, seroma, surgical site infection (SSI), pain scores, and duration of hospital stay. Data were analysed using SPSS version 21, with significance at P ≤ 0.05. Results: The mean age was higher in Group B (38.5 ± 11.1 years) than in Group A (33.91 ± 8.9 years) (P = 0.01). Group B had significantly lower incidences of oedema (42% vs 71%, P = 0.042), hematoma (21% vs 42%, P = 0.009), and seroma (11 vs 20, P = 0.007) compared to Group A. Although SSI rates were lower in Group B (25%) compared to Group A (50%), this difference was not statistically significant (P = 0.068). Pain scores were significantly lower in Group B (2.625 ± 0.7) compared to Group A (5.125 ± 0.7) (P < 0.0001). The duration of hospital stay was also shorter in Group B (3.75 ± 0.8 days) than in Group A (6.9 ± 1.08 days) (P < 0.0001). Conclusion: Chymotrypsin and trypsin significantly enhance post-operative recovery by reducing oedema, hematoma, seroma, pain scores, and hospital stay duration in inguinal hernia repair patients. These findings support incorporating enzymatic agents into post-operative care protocols to improve patient outcomes.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-12DOI: 10.54112/bcsrj.v2024i1.985
Q. Shakeel, S. Ashraf, F. Nadeem, K. Sehar, MR Butt, R. Aslam, MS Rasheed
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder among women of reproductive age, characterized by elevated androgen levels, ovarian cysts, and symptoms such as irregular menstrual cycles, hirsutism, and acne. PCOS is often associated with insulin resistance, which increases the risk of developing type 2 diabetes mellitus (T2DM). Objective: This study aimed to explore the relationship between PCOS and T2DM in women of reproductive age, focusing on the prevalence of symptoms, risk factors, and potential interventions. Methods: A cross-sectional study was conducted from April to June 2024, involving 100 women aged 18 to 43 at Sardar Begum Hospital and Cheema Family Hospital in Sialkot. Participants were divided equally into PCOS (n=50) and control groups (n=50). Data were collected on demographic and clinical characteristics, including HbA1c levels, using a structured form and laboratory tests. Descriptive statistics, independent samples t-tests, and chi-square tests analyzed the data. Results: The PCOS group exhibited a significantly higher prevalence of irregular menstrual cycles (87%), hirsutism (67%), and acne (40%) compared to the control group. Elevated HbA1c levels were observed in 25% of the PCOS group, with 15% having levels above 6.4%, indicating a heightened risk for T2DM. The mean HbA1c level was significantly higher in the PCOS group (6.2%) compared to the control group (5.5%). Additionally, 60% of women with PCOS reported a family history of diabetes, suggesting a genetic predisposition. Conclusion: Women with PCOS are at a significantly higher risk of developing T2DM. The study highlights the need for early screening and comprehensive management strategies to mitigate these risks. A multidisciplinary approach involving various healthcare professionals is essential for effective intervention and prevention. Further research is necessary to improve the understanding and treatment of these interconnected conditions.
{"title":"ASSOCIATION OF TYPE 2 DIABETES AMONG REPRODUCTIVE-AGED WOMEN HAVING POLYCYSTIC OVARIAN SYNDROME IN SIALKOT","authors":"Q. Shakeel, S. Ashraf, F. Nadeem, K. Sehar, MR Butt, R. Aslam, MS Rasheed","doi":"10.54112/bcsrj.v2024i1.985","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.985","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder among women of reproductive age, characterized by elevated androgen levels, ovarian cysts, and symptoms such as irregular menstrual cycles, hirsutism, and acne. PCOS is often associated with insulin resistance, which increases the risk of developing type 2 diabetes mellitus (T2DM). Objective: This study aimed to explore the relationship between PCOS and T2DM in women of reproductive age, focusing on the prevalence of symptoms, risk factors, and potential interventions. Methods: A cross-sectional study was conducted from April to June 2024, involving 100 women aged 18 to 43 at Sardar Begum Hospital and Cheema Family Hospital in Sialkot. Participants were divided equally into PCOS (n=50) and control groups (n=50). Data were collected on demographic and clinical characteristics, including HbA1c levels, using a structured form and laboratory tests. Descriptive statistics, independent samples t-tests, and chi-square tests analyzed the data. Results: The PCOS group exhibited a significantly higher prevalence of irregular menstrual cycles (87%), hirsutism (67%), and acne (40%) compared to the control group. Elevated HbA1c levels were observed in 25% of the PCOS group, with 15% having levels above 6.4%, indicating a heightened risk for T2DM. The mean HbA1c level was significantly higher in the PCOS group (6.2%) compared to the control group (5.5%). Additionally, 60% of women with PCOS reported a family history of diabetes, suggesting a genetic predisposition. Conclusion: Women with PCOS are at a significantly higher risk of developing T2DM. The study highlights the need for early screening and comprehensive management strategies to mitigate these risks. A multidisciplinary approach involving various healthcare professionals is essential for effective intervention and prevention. Further research is necessary to improve the understanding and treatment of these interconnected conditions.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-11DOI: 10.54112/bcsrj.v2024i1.984
J. Hussain, N. Noor, F. Rehman, A. Ilyas, S. Tofail
The emergence of Hepatitis E virus (HEV) infection presents a mounting apprehension in less developed areas. When contracted during pregnancy, this infection instigates dire ramifications, posing grave threats to the well-being of both the expectant mother and the developing fetus. Notably, HEV accounts for a substantial fraction of maternal fatalities, encompassing a range of 19% to 25%, while also contributing to a noteworthy 7-13% of neonatal deaths. The primary objective of this study is to delve into the intricate relationship between HEV infection and the ensuing consequences for maternal and fetal health during pregnancy. Objectives: To explore the e maternal and fetal outcomes in pregnant women with Hepatitis E. Methods: A prospective study design was implemented, and 160 pregnant women were enrolled. The study was conducted at a tertiary healthcare facility over the period spanning from April 2021 to September 2022 after fulfilling the inclusion criteria and consent form. The collected data were entered and analyzed by using SPSS version 23. Results: A total of 160 pregnant women enrolled in this study, the mean age 30.90±7.323 (Age Range 18-44); gestational age was divided into two groups ≥ 36 weeks 77(48.1%) compared with ≥ 36 weeks as 83(51.9%).The frequency distribution of table -2 showed postpartum hemorrhage 82(51.2%), disseminated intravascular coagulation 70(43.8%) and hepatic encephalopathy 46(28.8%). The mode of pregnancy termination due to hepatitis E virus infection showed induction of labor 64(40%), hysterectomy 111(69.4%), and dilation and evacuation (D&E) 84(52.5%). While comparing maternal HEV infection with other research variables, it was observed that there was a significant difference found in HEV-positive pregnant women and low birth weight (< 2500g), fetal scalp monitors during delivery, and hysterectomy as p-value < 0.05. Conclusion: A high mortality rate was evident in hepatitis E virus infection-affected pregnancies in this study. There is a need to educate pregnant ladies regarding preventive measures to avoid fulminant consequences. Emphasis should be given to following hygienic practices during pregnancy, and proper antenatal visits should be mandatory to educate the women.
{"title":"MATERNAL AND FETAL HEALTH CHALLENGES IN HEPATITIS E-INFECTED PREGNANCIES","authors":"J. Hussain, N. Noor, F. Rehman, A. Ilyas, S. Tofail","doi":"10.54112/bcsrj.v2024i1.984","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.984","url":null,"abstract":"The emergence of Hepatitis E virus (HEV) infection presents a mounting apprehension in less developed areas. When contracted during pregnancy, this infection instigates dire ramifications, posing grave threats to the well-being of both the expectant mother and the developing fetus. Notably, HEV accounts for a substantial fraction of maternal fatalities, encompassing a range of 19% to 25%, while also contributing to a noteworthy 7-13% of neonatal deaths. The primary objective of this study is to delve into the intricate relationship between HEV infection and the ensuing consequences for maternal and fetal health during pregnancy. Objectives: To explore the e maternal and fetal outcomes in pregnant women with Hepatitis E. Methods: A prospective study design was implemented, and 160 pregnant women were enrolled. The study was conducted at a tertiary healthcare facility over the period spanning from April 2021 to September 2022 after fulfilling the inclusion criteria and consent form. The collected data were entered and analyzed by using SPSS version 23. Results: A total of 160 pregnant women enrolled in this study, the mean age 30.90±7.323 (Age Range 18-44); gestational age was divided into two groups ≥ 36 weeks 77(48.1%) compared with ≥ 36 weeks as 83(51.9%).The frequency distribution of table -2 showed postpartum hemorrhage 82(51.2%), disseminated intravascular coagulation 70(43.8%) and hepatic encephalopathy 46(28.8%). The mode of pregnancy termination due to hepatitis E virus infection showed induction of labor 64(40%), hysterectomy 111(69.4%), and dilation and evacuation (D&E) 84(52.5%). While comparing maternal HEV infection with other research variables, it was observed that there was a significant difference found in HEV-positive pregnant women and low birth weight (< 2500g), fetal scalp monitors during delivery, and hysterectomy as p-value < 0.05. Conclusion: A high mortality rate was evident in hepatitis E virus infection-affected pregnancies in this study. There is a need to educate pregnant ladies regarding preventive measures to avoid fulminant consequences. Emphasis should be given to following hygienic practices during pregnancy, and proper antenatal visits should be mandatory to educate the women.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.54112/bcsrj.v2024i1.964
.. Quratulain, MA Zahid, W. Malak, Y. Ahmad, MA Arif, MS Riaz
Cholecystectomy on an emergency basis or being treated with antibiotics gives a success rate of up to 86%. Objectives: The primary purpose of the study is to compare conservative vs surgical management of acute cholecystitis. Methods: This comparative observational study was conducted at Gondal Hospital Lahore from January 2024 to March 2024. Data were collected from 210 patients from different age groups. Patients with a clinical and imaging-confirmed diagnosis of acute cholecystitis were included in the study. Data were gathered on demographics, clinical presentation, laboratory results, imaging findings, treatment specifics, and patient outcomes. Variables included age, gender, symptom duration, white blood cell count, C-reactive protein levels, imaging results, treatment type, hospital stay duration, complications, and recurrence rates. Results: Data were collected from 210 patients. The mean age was similar between groups (54.23±2.35 years for conservative vs. 56.01±2.51 years for surgical). Gender distribution was comparable, with 54.3% males and 45.7% females in the conservative group and 50.5% males and 49.5% females in the surgical group. The complication rates were higher in the conservative management group (14.3%) compared to the surgical management group (7.6%). Specific complications in the conservative group included perforation (3.8%), abscess formation (5.7%), and sepsis (4.8%), whereas the surgical group experienced wound infections (2.9%), bile duct injuries (1.9%), and postoperative bleeding (2.9%). Conclusion: It is concluded that surgical management of acute cholecystitis, mainly through cholecystectomy, offers superior outcomes compared to conservative management. Patients undergoing surgery experience higher symptom resolution rates, shorter hospital stays, lower recurrence rates, and fewer complications.
{"title":"EVALUATION OF CONSERVATIVE VS SURGICAL MANAGEMENT OF ACUTE CHOLECYSTITIS","authors":".. Quratulain, MA Zahid, W. Malak, Y. Ahmad, MA Arif, MS Riaz","doi":"10.54112/bcsrj.v2024i1.964","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.964","url":null,"abstract":"Cholecystectomy on an emergency basis or being treated with antibiotics gives a success rate of up to 86%. Objectives: The primary purpose of the study is to compare conservative vs surgical management of acute cholecystitis. Methods: This comparative observational study was conducted at Gondal Hospital Lahore from January 2024 to March 2024. Data were collected from 210 patients from different age groups. Patients with a clinical and imaging-confirmed diagnosis of acute cholecystitis were included in the study. Data were gathered on demographics, clinical presentation, laboratory results, imaging findings, treatment specifics, and patient outcomes. Variables included age, gender, symptom duration, white blood cell count, C-reactive protein levels, imaging results, treatment type, hospital stay duration, complications, and recurrence rates. Results: Data were collected from 210 patients. The mean age was similar between groups (54.23±2.35 years for conservative vs. 56.01±2.51 years for surgical). Gender distribution was comparable, with 54.3% males and 45.7% females in the conservative group and 50.5% males and 49.5% females in the surgical group. The complication rates were higher in the conservative management group (14.3%) compared to the surgical management group (7.6%). Specific complications in the conservative group included perforation (3.8%), abscess formation (5.7%), and sepsis (4.8%), whereas the surgical group experienced wound infections (2.9%), bile duct injuries (1.9%), and postoperative bleeding (2.9%). Conclusion: It is concluded that surgical management of acute cholecystitis, mainly through cholecystectomy, offers superior outcomes compared to conservative management. Patients undergoing surgery experience higher symptom resolution rates, shorter hospital stays, lower recurrence rates, and fewer complications.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.54112/bcsrj.v2024i1.976
I. Javed, S. Ashraf, N. Parveen, M. Jamil, W. Ghaffar, A. Sardar, MJ Qamar, MR Farooq, S. Saleem, F. Habib, M. Akram, Z. Javeed, M. Khalid, MI Latif, A. Rauf, F. Hussain, B. Ali, W. Hassan, N. Manzoor, M. Yousaf, S HUSSAIN
The current experimental study was conducted at Cotton Research Station, Bahawalpur during the cotton growing in 2022. The study was designed to evaluate the elite cotton genotypes based on their photosynthetic sustainability and other physiochemical attributes which could help in framing a selection criterion for the development of improved carton genotypes. The results revealed that highly significant variations were present among the elite cotton genotypes for studied morpho-physiological, photosynthetic and biochemical traits i.e., CLCV incidence percentage, number of bolls, sympodia per plant, boll weight, net photosynthetic rate, total chlorophyll contents, transpiration rate, stomatal conductance, sugar contents, total phenolic contents, ascorbic acid and seed cotton yield, which could be used in devising selection criteria for this election of parental material to be used in the hybridization program. Furthermore, the correlation coefficient analysis unveiled the strong correlation of seed cotton yield with transpiration rate, sugar contents, stomatal conductance, net photosynthetic rate, ginning out turn and sympodia per plant whereas a strong negative correlation was found for total phenolic contents. These results were also verified through the mean bar graphs and biplot graphs which show that these traits have the highest influence on seed cotton yield under the optimal condition.
{"title":"ROLE OF PHOTOSYNTHETIC STABILITY AND PHYSIO-CHEMICAL ATTRIBUTES IN THE SELECTION OF IMPROVED COTTON GENOTYPES IN ACTUAL FIELD CONDITIONS","authors":"I. Javed, S. Ashraf, N. Parveen, M. Jamil, W. Ghaffar, A. Sardar, MJ Qamar, MR Farooq, S. Saleem, F. Habib, M. Akram, Z. Javeed, M. Khalid, MI Latif, A. Rauf, F. Hussain, B. Ali, W. Hassan, N. Manzoor, M. Yousaf, S HUSSAIN","doi":"10.54112/bcsrj.v2024i1.976","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.976","url":null,"abstract":"The current experimental study was conducted at Cotton Research Station, Bahawalpur during the cotton growing in 2022. The study was designed to evaluate the elite cotton genotypes based on their photosynthetic sustainability and other physiochemical attributes which could help in framing a selection criterion for the development of improved carton genotypes. The results revealed that highly significant variations were present among the elite cotton genotypes for studied morpho-physiological, photosynthetic and biochemical traits i.e., CLCV incidence percentage, number of bolls, sympodia per plant, boll weight, net photosynthetic rate, total chlorophyll contents, transpiration rate, stomatal conductance, sugar contents, total phenolic contents, ascorbic acid and seed cotton yield, which could be used in devising selection criteria for this election of parental material to be used in the hybridization program. Furthermore, the correlation coefficient analysis unveiled the strong correlation of seed cotton yield with transpiration rate, sugar contents, stomatal conductance, net photosynthetic rate, ginning out turn and sympodia per plant whereas a strong negative correlation was found for total phenolic contents. These results were also verified through the mean bar graphs and biplot graphs which show that these traits have the highest influence on seed cotton yield under the optimal condition.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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