Polycystic Kidney Disease with Breast Nodules in a Male: A Case Report

Caitlyn Natasha Horyono, Borries Foresto Buharman
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Abstract

Background: Polycystic kidney disease is a multisystem and progressive congenital kidney disorder characterized by kidney enlargement and the growth of cysts in the kidneys and other organs. Autosomal dominant polycystic kidney disease (ADPKD) is the most common type of inherited kidney disorder and is observed in 1/500 – 1/1000 people. The diagnosis is usually made by a positive family history , and the Ravine ultrasonographic criteria assess the age and number of cysts in both kidneys. Case presentation: A 37-year-old male was reported with complaints of intermittent hematuria and a painless lump in the right breast for the last 6 years. Patients routinely drink herbal medicine when symptoms appear. Abdominal physical examination revealed renal ballottement. The lump in the right breast is palpable as a lump ± 1 cm from the nipple. No abnormalities in kidney or liver function were found on laboratory examination. Ultrasound was performed, and polycystic kidney disease was obtained in both kidneys and liver, as well as a hypervascular solid nodule in the right breast. The patient was given antibiotics and antifibrinolytics. Healthy lifestyle education is also provided to patients. The patient was then referred for a biopsy of the nodule. Conclusion: Autosomal dominant polycystic kidney disease (ADPKD) is a common disease but only a few cases of ADPKD are accompanied by nodules in the breast, so a further approach is needed.
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男性多囊肾伴乳房结节:病例报告
背景:多囊肾是一种多系统、进行性的先天性肾脏疾病,其特征是肾脏肿大以及肾脏和其他器官中囊肿的生长。常染色体显性多囊肾(ADPKD)是最常见的遗传性肾脏疾病,发病率为 1/500 - 1/1000。通常通过阳性家族史和拉文超声波标准评估双肾囊肿的年龄和数量即可确诊。病例介绍:一名 37 岁的男性患者主诉间歇性血尿和右侧乳房无痛性肿块已有 6 年之久。患者在出现症状时经常喝中药。腹部体格检查显示为肾性血尿。右侧乳房可触及肿块,肿块距离乳头 ± 1 厘米。实验室检查未发现肝肾功能异常。进行了超声波检查,发现肾脏和肝脏均有多囊肾病变,右侧乳房也有一个高血管实性结节。患者接受了抗生素和抗纤维蛋白溶解剂治疗。此外,还对患者进行了健康生活方式教育。随后,患者被转诊进行结节活检。结论常染色体显性多囊肾病(ADPKD)是一种常见疾病,但只有少数 ADPKD 病例伴有乳房结节,因此需要进一步研究。
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