Eating behavior in patients with metabolically associated fatty liver disease

A. A. Khalashte, E. A. Lyalyukova, S. K. Zhachemuk, Z. A. Beslangurova, G. N. Zhernakova
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Abstract

The purpose of this study was to study the phenotypes of eating behavior in patients with NAFLD and their determining factors. Discussion: fatty liver disease has a high prevalence (24-26%) with an upward trend in both developed and developing countries, and in the coming years may become one of the main causes of liver transplantation. The clinical features of the disease are in most cases its asymptomatic course, which can progress to fibrosis/cirrhosis and is associated with the risk of a number of serious extrahepatic diseases (cardiovascular, oncological and others). The mechanisms underlying the formation of increased health risks and disease prognosis are multifactorial. Metabolic disorders, orthorexia nervosa, eating disorders and vegetative effects are considered as possible pathogenetic mechanisms for increasing the risk of NAFLD incidence. Conclusion: the study showed that complex behavioral psycho-social factors are involved in the pathogenesis of NAFLD, and changing eating behavior is an important component of therapy. Dysfunctional eating behavior can be a barrier to long-term success from therapy.
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代谢性脂肪肝患者的饮食行为
本研究旨在研究非酒精性脂肪肝患者饮食行为的表型及其决定因素。讨论:脂肪肝在发达国家和发展中国家的发病率都很高(24%-26%),且呈上升趋势,未来几年可能成为肝移植的主要原因之一。该病的临床特点是在大多数情况下无症状,但可发展为肝纤维化/肝硬化,并与一系列严重肝外疾病(心血管疾病、肿瘤和其他疾病)的风险相关。健康风险和疾病预后增加的形成机制是多因素的。代谢紊乱、神经性厌食症、饮食失调和植物神经效应被认为是增加非酒精性脂肪肝发病风险的可能致病机制。结论:研究表明,非酒精性脂肪肝的发病机制涉及复杂的行为社会心理因素,改变饮食行为是治疗的重要组成部分。功能失调的饮食行为会阻碍治疗的长期成功。
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