Pulmonary Embolism in Donor Lungs—Incidence and Management

Juliano Lentz Carvalho, Suresh Keshavamurthy
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Abstract

In efforts to decrease the mortality on the waiting list for lung transplantation, alternatives to increase the donor pool have been explored. Caution must be used when accepting donor lungs with pulmonary embolism (PE), as prior evidence has shown mixed results after transplantation of donor lungs with PE. However, the mere diagnosis of PE on imaging should not be the sole reason for the exclusion of these donors for transplant, and they should be reviewed as any other donor. A comprehensive evaluation should be performed for every donor, with a special focus on abnormalities of gas exchange and gross pathologic characteristics during procurement.
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捐献肺中的肺栓塞--发生率和处理方法
为了降低肺移植等待名单上的死亡率,人们一直在探索增加供体库的替代方法。在接受患有肺栓塞(PE)的供肺时必须谨慎,因为之前的证据显示,患有肺栓塞的供肺在移植后的结果好坏参半。然而,不能仅凭影像学诊断出 PE 就将这些供体排除在移植之外,而应像对待其他供体一样对他们进行审查。应对每一位捐献者进行全面评估,重点关注气体交换异常和采集过程中的重大病理特征。
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