Clinical and pathological study of patients with fibrocystic disease of breast in tertiary care hospital of Gurugram, Haryana

Sapna Goel, Bhumika Singhal, Anil Kumar, Kanwar Singh, Tanay Arora, Aditi Narayan
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Abstract

A fibrocystic breast disease group of benign breast diseases that consists of fibrocystic breast disease, breast cyst, breast abscess, duct ectasia, cyclic and non-cyclic mastalgia, Gynaecomastia and Mondor's disease. Abnormal hormonal balance and cellular interactions mediated growth factors leading to ductal and cellular hyperplasia is the main pathophysiological cause of the disease. This prospective observational study was conducted on 100 SGT medical college and hospital patients from January 2021 to august 2022 to assess the detailed clinicopathological study of patients with fibrocystic disease breast diagnosed clinically with relevant investigations. In our study, we found that fibroadenoma is the maximum among all Fibrocystic breast diseases, i.e. 34%, with the majority between 11-30 years. It rises in the 2 decade of life and peaks in the 4 decade. Non-cyclic mastalgia constituted 29% of the total cases, with most patients lying in the age group of 31-50 years, where mastalgia was the presenting complaint in most cases. Inflammatory breast diseases formed 4% of the total, with the main presenting symptoms being mastalgia, fever and nipple discharge. Again, it mainly included patients from the age group of 31-50 years. Gynaecomastia and breast abscess were diagnosed in 3 cases, with all lumping on the right side of the breast.Our study attempted to derivate the spectrum of breast diseases in different age groups among patients reporting to SGT medical college and hospital, SGT University, Gurugram, Haryana. Apart from the incidence of various fibrocystic diseases, various other facts were recorded. Benign breast lesions were recorded to comprise the bulk of the patients presenting with breast disorders and were maximum in the reproductive age group. Breast sclerosing adenosis should be identified by excluding the malignancy. Most Fibrocystic breast diseases have been managed conservatively.
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哈里亚纳邦古鲁格拉姆三级医院乳腺纤维囊性疾病患者的临床和病理研究
纤维囊性乳腺病是一组良性乳腺疾病,包括纤维囊性乳腺病、乳腺囊肿、乳腺脓肿、导管异位症、周期性和非周期性乳痛症、妇科乳腺增生症和蒙多病。激素平衡异常和细胞相互作用介导的生长因子导致导管和细胞增生是该病的主要病理生理原因。这项前瞻性观察研究于 2021 年 1 月至 2022 年 8 月期间对 100 名 SGT 医学院和医院的患者进行了临床病理研究,以评估经临床诊断并进行相关检查的乳腺纤维囊病患者的详细临床病理研究。在我们的研究中,我们发现乳腺纤维腺瘤是所有乳腺纤维囊性疾病中发病率最高的,占 34%,大多数患者年龄在 11-30 岁之间。乳腺纤维腺瘤的发病率在生命的第 2 个 10 年上升,在第 4 个 10 年达到高峰。非周期性乳房胀痛占总病例的 29%,大多数患者年龄在 31-50 岁之间,乳房胀痛是大多数病例的主诉。炎症性乳腺疾病占总病例的 4%,主要表现为乳痛、发热和乳头溢液。同样,它主要包括 31-50 岁年龄组的患者。我们的研究试图在哈里亚纳邦古勒格拉姆 SGT 大学 SGT 医学院和医院就诊的患者中推导出不同年龄组的乳腺疾病谱。除了各种纤维囊肿疾病的发病率外,还记录了其他各种情况。据记录,乳腺良性病变占乳腺疾病患者的大部分,在育龄组中发病率最高。乳腺硬化性腺病应排除恶性肿瘤。大多数纤维囊性乳腺疾病都得到了保守治疗。
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