ALLOPECIA AREATA AND PERIODONTITIS: A CASE REPORT

Virna-Maria Tsitou, Dimitrios Rallis, Mariana Tsekova, Nikolay Yanev
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Abstract

This case report examines the interrelationship between periodontitis and Alopecia areata (AA), an autoimmune condition, within the broader context of the impact of oral health on systemic diseases. The concept of "oral primary foci," encompassing various oral pathologies such as periodontitis, dentoalveolar abscesses, and pulpal necrosis, is highlighted as a key factor in systemic diseases and complications. The report details the case of a 50-year-old female patient with AA who exhibited significant improvement in her condition following periodontal treatment. This improvement underscores the potential systemic influence of oral health conditions, particularly periodontitis, which is characterized by a dynamic interplay between bacterial infection and the host's immune response. The presence of autoantibodies in periodontitis suggests an autoimmune component, potentially linking it to autoimmune diseases like AA. The patient's case also aligns with the epidemiological data on AA, emphasizing its complex etiology and association with various systemic conditions. The report concludes that effective management of oral health, especially periodontal diseases, is crucial in the systemic health and management of conditions such as AA. It advocates for a holistic approach in healthcare, integrating oral health as a fundamental aspect of managing systemic diseases, and calls for continued research into the mechanisms connecting oral and systemic autoimmune responses. This research is vital for developing comprehensive treatment strategies that address both oral and systemic health, thereby enhancing overall patient outcomes.
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斑秃和牙周炎:一份病例报告
本病例报告在口腔健康对全身性疾病影响的大背景下,探讨了牙周炎与自身免疫性斑秃(AA)之间的相互关系。报告强调了 "口腔原发病灶 "这一概念,它包括牙周炎、牙槽脓肿和牙髓坏死等各种口腔病症,是导致全身性疾病和并发症的关键因素。报告详细介绍了一名 50 岁女性 AA 患者的病例,她的病情在接受牙周治疗后有了明显改善。这种改善强调了口腔健康状况对全身的潜在影响,尤其是牙周炎,其特点是细菌感染和宿主免疫反应之间的动态相互作用。牙周炎中自身抗体的存在表明存在自身免疫因素,可能与 AA 等自身免疫性疾病有关。该患者的病例也与 AA 的流行病学数据相吻合,强调了其复杂的病因以及与各种系统性疾病的关联。报告的结论是,有效管理口腔健康,尤其是牙周疾病,对全身健康和 AA 等疾病的管理至关重要。报告提倡在医疗保健中采用整体方法,将口腔健康作为管理全身性疾病的一个基本方面,并呼吁继续研究口腔和全身自身免疫反应的关联机制。这项研究对于制定针对口腔和全身健康的综合治疗策略至关重要,从而提高患者的整体治疗效果。
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